Playboy: Has no religion, in your estimation, ever offered anything of constructive value to human life?
Ayn Rand: Qua religion, no - in the sense of blind belief, belief unsupported by, or contrary to, the facts of reality and the conclusions of reason. Faith, as such, is extremely detrimental to human life: it is the negation of reason. But you must remember that religion is an early form of philosophy, that the first attempts to explain the universe, to give a coherent frame of reference to man's life and a code of moral values, were made by religion, before men graduated or developed enough to have philosophy. And, as philosophies, some religions have very valuable moral points. They may have a good influence or proper principles to inculcate, but in a very contradictory context and, on a very - how should I say it? - dangerous or malevolent base: on the ground of faith. [Playboy interview with Ayn Rand]
...if devotion to truth is the hallmark of morality, then there is no greater, nobler, more heroic form of devotion than the act of a man who assumes the responsibility of thinking.... the alleged short-cut to knowledge, which is faith, is only a short-circuit destroying the mind.
http://atheism.about.com/library/quotes/bl_q_ARand.htm