DU scientists and others please splain this to me. Some guy gets on Tucker Calson

[Maraya1969]

(alarm bells ok) and says this Australian team has found that a combination of a hydroxychloroquine and Azithromycin CURED Covid 19 .

It is reported in the Daily Wire, (Don't flame me I'm just reporting here!)

https://www.dailywire.com/news/french-peer-reviewed-study-our-treatment-cured-100-of-coronavirus-patients?fbclid=IwAR2DaH9C0ZumXaLrEUwuUof9ZNi7BgDXJ1QkvTMyycfRqqUBBaWFmw-gKlQ

Anyway, I was able to find the actual paper and though I am not a scientist it sounds promising. I imagine that groups all over the world are trying to find a cure now because they would become famous and rich really fast.


Here is a link to an update from the paper. Please peruse...............

https://www.mediterranee-infection.com/wp-content/uploads/2020/03/Hydroxychloroquine_final_DOI_IJAA.pdf



French Confirmed COVID-19 patients were included in a single arm protocol from early
March to March 16th, to receive 600mg of hydroxychloroquine daily and their viral load in
nasopharyngeal swabs was tested daily in a hospital setting. Depending on their clinical
presentation, azithromycin was added to the treatment. Untreated patients from another center
and cases refusing the protocol were included as negative controls. Presence and absence of
virus at Day6-post inclusion was considered the end point.
Results
Six patients were asymptomatic, 22 had upper respiratory tract infection symptoms and eight
had lower respiratory tract infection symptoms.
Twenty cases were treated in this study and showed a significant reduction of the viral
carriage at D6-post inclusion compared to controls, and much lower average carrying duration
than reported of untreated patients in the literature. Azithromycin added to
hydroxychloroquine was significantly more efficient for virus elimination.


Conclusion


Despite its small sample size our survey shows that hydroxychloroquine treatment is
significantly associated with viral load reduction/disappearance in COVID-19 patients and its
effect is reinforced by azithromycin.


4
Please cite this work as Gautret et al. (2020) Hydroxychloroquine and azithromycin as a treatment of
COVID‐19: results of an open‐label non‐randomized clinical trial. International Journal of
Antimicrobial Agents – In Press 17 March 2020 – DOI : 10.1016/j.ijantimicag.2020.105949
Despite its small sample size our survey shows that hydroxychloroquine treatment is
significantly associated with viral load reduction/disappearance in COVID-19 patients and its
effect is reinforced by azithromycin.
Key words: 2019-nCoV; SARS-CoV-2; COVID-19; hydroxychloro

[Maraya1969]

1. I would like to add that the disingenuous way this clown reported about it on TV

really pisses me off. He sounds like a mini-Trump with all his hype.

[SWBTATTReg]

2. This must be related to the HIV treatment/therapy/? that I read about recently, where they...

essentially removed the entire viral load(?) within an HIV patient, they couldn't detect anything. I am guessing here...

[magicarpet]

8. Antiretroviral drugs for HIV and antimalarial drugs are showing great promise for COVID-19 pati.....

.... of COVID-19 patients.

Antiretrovirals used for HIV are being found effective for significantly dropping viral loads of COVID-19 patients.


Protease Inhibitors (PIs)
These drugs block a protein that infected cells need to put together new HIV virus particles.

Atazanavir or ATV (Reyataz)
Darunavir or DRV (Prezista)
Fosamprenavir or FPV (Lexiva)
Indinavir or IDV (Crixivan)
Lopinavir + ritonavir, or LPV/r (Kaletra)
Nelfinavir or NFV (Viracept)
Ritonavir or RTV (Norvir)
Saquinavir or SQV (Invirase, Fortovase)
Tipranavir or TPV (Aptivus)

[SWBTATTReg]

10. Thanks for confirming. Being that I have friends w/ HIV, I have an interest in these articles ...

that do come out on such therapies. I assume that the names you mentioned are the specific and generic names for the same thing, i.e., lansoprazole vs. prevacid? Thanks and be safe.

[magicarpet]

12. See comment # 11

[magicarpet]

11. More info antiretrovirals and antimalarials,...

... with hopes to benefit COVID-19 patients.

*~*~*~
~*~*~*
Medication proving to be beneficial to COVID-19 patients.

Prescription drugs already on the market but tested for other uses, doctor may cross prescribe, or FDA allow for compassionate use, IND.

An Investigational New Drug Application (IND) is a request for authorization from the Food and Drug Administration (FDA) to administer an investigational drug or biological product to humans.May 14, 2019

These have shown promising results for COVID-19 patients.

Anti retro virals - medications specific to HIV,
* Lopinavir
* Ritonavir
Show promising results for COVID-19 patients.

Out of Japan, by a pharma lab which is a subsidiary of Fuji Film,
* FAVIPIRAVIR, AKA AVIGAN Shows promising results for COVID-19 patients.

Out of France, Sandfi Labs, anti malarial,
* HYDROOXYCHLOROQUINE, AKA CHLOROQUINE, AKA PIAQUENIL, shows promise with COVID-19 patients, previously used for MERS & SARS.

If the above medication is used with *ZINC it boosts results.

* AZITHROMYCIN, anti malarial shows promise with COVID-19 patients.

* REMDESVIR, Specific to COVID-19 currently under drug study trial.

Antiviral technique known to FDA, nasal irrigation/flush with saline solution. If nasal cavities irrigated once a day viral count is significantly diminished.

AKA NETI POT, Google,
Google - nasal irrigation

DO NOT USE DIRECT TAP WATER, the water must be sterile bring to rolling boil then cool.

Saline solution formula,
I/2 teaspoon salt
Per 3 ounces of (sterile) water

* TAMIFLU, shows positive results for COVID-19 sufferers if administered within 24hrs of onset.

* VITAMIN D, in pill form, be known 20,000 international units of vitamin D is derived from 1/2hr of sun exposure.

* ZINC vitamin supplements boost the immune system.

[bronxiteforever]

3. Not a scientist but this article in the Guardian yesterday

Had a brief lay person’s description of this. Here is the excerpt:

The anti-malaria drug: chloroquine
Chloroquine is a cheap, widely available drug that has been routinely used since 1945 against malaria and other conditions and can be safely taken by pregnant women and children. Lab studies found the antiviral drug was effective against the coronavirus, at least in a petri dish, and results from a small French study in 24 patients, announced this week, suggested that it could quicken recovery.

Doctors said 25% of patients who received the drug tested positive for the virus after six days, compared with 90% of those who did not receive it. Chloroquine and a related drug, hydroxychloroquine, are among the four treatments tested in an international clinical trial, announced on Wednesday by the World Health Organization (WHO), and the UK has added chloroquine to its list of medicines under export controls.

https://www.theguardian.com/science/2020/mar/19/prospects-treatment-coronavirus-drugs-vaccines?CMP=Share_iOSApp_Other

[Yavin4]

4. If he's on Tucker Calson, he's a fraud.n/t

[Hoyt]

5. There is an article today from France24, state owned, where doctors cite

their experience, which was positive. Similar articles from China, WSJ on docs here, Korea, etc. Sorry, I’m on phone or I’d provide a link.

Honestly, I’m not as ticked at trump as some for offering some hope in this regard. But, that’s about the only thing I’m not ticked at in all this.

I think some of the docs appearing with trump need to loosen up on their double-blind, long-term clinical studies in this situation. Apparently there is no real downside to using these meds in a closely monitored hospital setting vs. doing nothing.

And it’s a cheap med, readily available. If I believed in conspiracy theories, I’d say some of these docs must be stockholders in the big bucks pharmaceutical companies looking to make a killing.

[uponit7771]

6. +1, how big of a varied sample size to the doctors need? It seems like for sever cases this medicine

... would be something vs nothing

[Midnightwalk]

7. I think of it like this

Teams all over the world will be trying various treatments to see if they speed recovery or lessen symptoms.

We will be hearing optimistic news every time there is a positive result.

Figuring what is really effective is going to take work, controlled trials and time.

If we find treatments that work it will take more time to ramp up production world wide.

If we have effective treatments available that makes it easier to figure out how to get past the current large scale isolation.

In other words expect and hope to hear more encouraging news but don’t expect anything to get better very quickly.

[AJT]

9. Another big reason to flatten the spread for as long as possible

so treatments can be tested and safely released.