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struggle4progress

(118,236 posts)
Tue May 12, 2020, 06:16 AM May 2020

Hydroxychloroquine doesn't work

... The study was published Monday in the Journal of the American Medical Association. It follows a study published Thursday in the New England Journal of Medicine that also showed the drug doesn’t fight the virus ...

“The nail has virtually been put in the coffin of hydroxychloroquine,” said Dr. William Schaffner, an infectious disease expert and longtime adviser to the US Centers for Disease Control and Prevention.

In the most recent study, researchers at the University at Albany looked at 1,438 patients with coronavirus who were admitted to 25 New York City area hospitals. After statistical adjustments, the death rate for patients taking hydroxychloroquine was similar to those who did not take the drug. The death rate for those taking hydroxychloroquine plus the antibiotic azithromycin, was also similar.

However, the patients who took the drug combination were more than twice as likely to suffer cardiac arrest during the course of the study. Heart issues are a known side effect of hydroxychloroquine ...

https://www.kvor.com/news/yet-another-study-shows-hydroxychloroquine-doesnt-work-against-covid-19/

20 replies = new reply since forum marked as read
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Hydroxychloroquine doesn't work (Original Post) struggle4progress May 2020 OP
Hydroxycholoroquine failed to help in 2 big studies struggle4progress May 2020 #1
And it causes heart attacks. It's worse than useless against Covid-19, it's deadly. nt SunSeeker May 2020 #2
Hydroxychloroquine falls out of use in Hudson County struggle4progress May 2020 #3
Schumer asks VA why it's using hydroxychloroquine struggle4progress May 2020 #4
Hydroxychloroquine truther Ingraham begs Trump to overturn FDA's warning struggle4progress May 2020 #5
County reverses decision to file amicus brief regarding hydroxychloroquine ban (NV) struggle4progress May 2020 #6
What to do with all that hydroxychloroquine? struggle4progress May 2020 #7
Well, I won't be praying for a malaria outbreak. We've got our hands full as it is. nt littlemissmartypants May 2020 #13
Admin ignored concern over hydroxychloroquine: Fired US scientist struggle4progress May 2020 #8
Drug whim costs millions, as mania wanes struggle4progress May 2020 #9
Science Chloroquine witchdoctor Didier Raoult: barking mad and dangerous jberryhill May 2020 #10
Not a random assignment study, we need that to be certain Cicada May 2020 #11
But that guy down by the river said it's perfect! Snarkoleptic May 2020 #12
But, but, Donny had a feeling! tanyev May 2020 #14
Meet The Doctor Behind The Hydroxychloroquine Treatment, And What's Next For Its Use jmg257 May 2020 #15
And if it doesn't, not so great. LisaL May 2020 #17
Yep - pretty sure this guy started the whole love affair with it. jmg257 May 2020 #19
Dr. Zelenko was adding zinc. LisaL May 2020 #20
Bet a lot of day traders made fortunes off a drug the prez was pushing. spanone May 2020 #16
And now hospitals are stuck with stockpiles of it. LisaL May 2020 #18

struggle4progress

(118,236 posts)
1. Hydroxycholoroquine failed to help in 2 big studies
Tue May 12, 2020, 06:18 AM
May 2020

Lydia Ramsey
13 hours ago

... In NEJM, an observational study looked at 1,376 patients admitted to Columbia University Irving Medical Center in New York City, 811 of who were given hydroxychloroquine. It found that administering hydroxychloroquine was not associated with an increased or lowered risk of intubation or death compared to those who didn't receive hydroxychloroquine.

The patients who received hydroxychloroquine tended to be more severely ill than those who did not receive the drug. Authors of both studies noted that randomized controlled trials — which assign patients either to the medication or a placebo control at random —are needed ...

https://www.businessinsider.com/jama-nejm-studies-on-hydroxychloroquine-for-coronavirus-patients-2020-5

struggle4progress

(118,236 posts)
3. Hydroxychloroquine falls out of use in Hudson County
Tue May 12, 2020, 06:20 AM
May 2020

By Daniel Israel - May 11, 2020

... Dr. Tucker Woods, Chief Medical Officer at Christ Hospital in Jersey City, said that Hydroxychloroquine is no longer used for the most part, in favor of more promising treatments ...

“After some studies that were published here in the United States, now I think it’s lost a lot of its initial hopes.”

Dr. Nizar Kifaieh struck a similar tone at Hudson Regional Hospital in Secaucus ...

https://hudsonreporter.com/2020/05/11/hydroxychloroquine-falls-out-of-use-in-hudson-county/

struggle4progress

(118,236 posts)
4. Schumer asks VA why it's using hydroxychloroquine
Tue May 12, 2020, 06:22 AM
May 2020

By Michael O'Keeffe
Updated May 10, 2020 7:31 PM

Sen. Chuck Schumer asked the Department of Veterans Affairs on Sunday to explain why it continues to use hydroxychloroquine to treat patients with the coronavirus, saying the anti-malaria drug is not only ineffective in treating COVID-19 but has also been linked to life-threatening cardiac arrests.

Schumer (D-N.Y.) also demanded to know why the agency recently spent $208,000 for a bulk purchase of hydroxychloroquine, which President Donald Trump and his allies have pushed, without scientific evidence, as a treatment for the coronavirus.

The Senate minority leader questioned whether veterans have been clandestinely given the drug ...

https://www.newsday.com/news/health/coronavirus/schumer-coronavirus-hydroxychloroquine-veterans-1.44535052

struggle4progress

(118,236 posts)
5. Hydroxychloroquine truther Ingraham begs Trump to overturn FDA's warning
Tue May 12, 2020, 06:24 AM
May 2020

ROGER SOLLENBERGER

MAY 9, 2020 1:55AM (UTC)
Fox News host Laura Ingraham, who has publicly acknowledged her lack of medical expertise, made a personal appeal to President Donald Trump on her broadcast to "pull back" a "misguided" FDA warning about an unproven drug treatment for the new coronavirus.

"We now have multiple studies across the globe and reports from treating physicians regarding the safety and efficacy of hydroxychloroquine," Ingraham during a Wednesday segment. "Along with hundreds of thousands of lupus and rheumatoid arthritis patients who've been taking the drug for decades without complications. Time for the FDA — the president himself — to pull back on the misguided and unnecessary warning that was issued a few weeks ago" ...

https://www.salon.com/2020/05/08/hydroxychloroquine-truther-laura-ingraham-who-is-not-a-doctor-begs-trump-to-overturn-fdas-warning/

"I'm really a necrophiliac!"

struggle4progress

(118,236 posts)
6. County reverses decision to file amicus brief regarding hydroxychloroquine ban (NV)
Tue May 12, 2020, 06:28 AM
May 2020

By Carla O'Day
May 8, 2020

Washoe County commissioners on Thursday rescinded a decision made last month that would ask the District Attorney to file a legal brief challenging a state decision that banned the use of certain drugs to treat COVID-19 patients outside a hospital setting ...

Commissioners decided April 21 to file an amicus brief supporting a challenge by the Nevada Osteopathic Medical Association to the Nevada State Board of Pharmacy’s emergency regulation banning the use of choloroquine and hydroxychloroquine to treat non-hospitalized coronavirus patients. An amicus brief is a document by a non-party to a lawsuit that is intended to outline legal arguments for the benefit of the court ...

https://thisisreno.com/2020/05/county-reverses-decision-to-file-amicus-brief-regarding-hydroxychloroquine-ban/

struggle4progress

(118,236 posts)
7. What to do with all that hydroxychloroquine?
Tue May 12, 2020, 06:29 AM
May 2020

By Emily Kopp and Thomas McKinless
Posted May 8, 2020 at 8:26am

The Strategic National Stockpile since April 1 has shipped to states 28 million tablets of a malaria drug that President Donald Trump touted as a potential treatment for COVID-19. States received millions more from donations or taxpayer-funded purchases.

But after doubts arose about whether the drug, hydroxychloroquine sulfate, is safe and effective for the coronavirus-based disease, states are donating supplies to patients who need them for other reasons, seeking refunds or weighing what to do with them ...

https://www.rollcall.com/2020/05/08/what-to-do-with-all-that-hydroxychloroquine-trump-touted/

struggle4progress

(118,236 posts)
8. Admin ignored concern over hydroxychloroquine: Fired US scientist
Tue May 12, 2020, 06:31 AM
May 2020

May 06, 2020 12:03 PM IST

A fired American scientist has alleged that the Trump administration ignored the concern of doctors in the US over the importation of hydroxychloroquine from "uninspected factories" in India and Pakistan and flooded the country with the "unproven and potentially dangerous" anti-malarial drug.

In a complaint filed on Tuesday before the US Office of Special Counsel, which oversees the protection of whistleblowers, Rick Bright alleged that top officials of the Department of Health and Human Services (HHS) repeatedly ignored his messages and that of others over the Personal Protective Equipment (PPE) and medicines like hydroxychloroquine in particular ...

https://www.cnbctv18.com/politics/trump-admin-ignored-concern-over-hydroxychloroquine-import-from-in-india-pak-fired-us-scientist-5854801.htm

struggle4progress

(118,236 posts)
9. Drug whim costs millions, as mania wanes
Tue May 12, 2020, 06:34 AM
May 2020

By Anna Edney
May 5, 2020, 4:28 PM EDT

... as quickly as pharmacies were drained of the pills, the tide has now turned against hydroxychloroquine and its chemical cousin, chloroquine. Regulators and scientists have raised concerns about potentially serious side effects, while Gilead Sciences Inc.’s antiviral therapy remdesivir was cleared for U.S. use. Some hospitals, including Mount Sinai Health System in New York, no longer include the drug in their treatment regimen for Covid-19.

The surge resulted in shortages that left patients who’d long taken the medication to treat lupus and rheumatoid arthritis hunting for alternatives. To help get more drugs to market, the Food and Drug Administration has allowed overseas manufacturing facilities that were previously sanctioned for quality violations to begin producing it for U.S. patients.

Hydroxychloroquine prescriptions jumped to 298,660 during the week of March 20, more than doubling from a week earlier, according to data compiled by Bloomberg Intelligence. But prescriptions have now plummeted back to nearly normal levels, and there are signs a speed-up in manufacturing is slowing ...

https://www.bloomberg.com/news/articles/2020-05-05/trump-s-virus-drug-whim-costs-millions-even-as-the-mania-wanes

 

jberryhill

(62,444 posts)
10. Science Chloroquine witchdoctor Didier Raoult: barking mad and dangerous
Tue May 12, 2020, 07:01 AM
May 2020


https://forbetterscience.com/2020/04/22/chloroquine-witchdoctor-didier-raoult-barking-mad-and-dangerous/

This is why chloroquine proponents changed their stance and now scream that it is wrong to treat very sick COVID-19 patients with chloroquine. Instead, they insist that the drug must be given very early during infection or even prophylactically, i.e., to healthy and asymptomatic people only. Given the evidence that the coronavirus is apparently lethal for less than 1% of the infected, you can see where this is going. The safest way to successfully heal with witchdoctor magic is to treat those who are not really ill and recover anyway.

Cicada

(4,533 posts)
11. Not a random assignment study, we need that to be certain
Tue May 12, 2020, 07:13 AM
May 2020

A random assignment study is under way. That will be something we can rely on.

tanyev

(42,522 posts)
14. But, but, Donny had a feeling!
Tue May 12, 2020, 08:07 AM
May 2020

And he’s always, always, always, always, always, always, always, always, always, always, always, always, always, always, always, always right.

jmg257

(11,996 posts)
15. Meet The Doctor Behind The Hydroxychloroquine Treatment, And What's Next For Its Use
Tue May 12, 2020, 08:24 AM
May 2020
ROSLYN, N.Y. (CBSNewYork) – One New York doctor claims to have kept hundreds of coronavirus patients out of the hospital with a cocktail of medications.

It’s been criticized as unproven, but now a major hospital in New York is launching a clinical trial based on the treatment, reports CBS2’s Carolyn Gusoff.

In the village of Kiryas Joel in Orange County, Dr. Vladimir Zelenko, a self-described “country doctor,” says a cocktail of medicines keeps his patients alive.

Weeks ago, he recorded this message for President Donald Trump: “I’m seeing tremendous positive results. I haven’t sent any patient to the hospital yet, even though I’ve treated hundreds already.”


https://newyork.cbslocal.com/2020/04/30/coronavirus-exclusive-meet-the-doctor-behind-the-hydroxychloroquine-treatment-for-covid-19/


Hydroxychloroquine got the president’s attention, and swiftly got him criticism for touting unfounded cures.

“There are people dying,” said Trump at the time. “If it works, that would be great.”

LisaL

(44,972 posts)
17. And if it doesn't, not so great.
Tue May 12, 2020, 08:26 AM
May 2020

Which is why unproven drugs aren't normally used to treat diseases before one has a clue if it helps or hurts.

jmg257

(11,996 posts)
19. Yep - pretty sure this guy started the whole love affair with it.
Tue May 12, 2020, 08:30 AM
May 2020

They have a had a big share of cases in the county...enough that Cuomo was asked to block off the area like he did in with new Rochell (he refused).

LisaL

(44,972 posts)
20. Dr. Zelenko was adding zinc.
Tue May 12, 2020, 08:42 AM
May 2020

Zinc actually has anti-viral properties so might do a little something.

LisaL

(44,972 posts)
18. And now hospitals are stuck with stockpiles of it.
Tue May 12, 2020, 08:27 AM
May 2020

Some hospitals apparently are using it as a standard of care. When it seems to hurt (cardiovascular side effects) instead of helping.

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