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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsHydroxychloroquine doesn't work
... The study was published Monday in the Journal of the American Medical Association. It follows a study published Thursday in the New England Journal of Medicine that also showed the drug doesnt fight the virus ...
The nail has virtually been put in the coffin of hydroxychloroquine, said Dr. William Schaffner, an infectious disease expert and longtime adviser to the US Centers for Disease Control and Prevention.
In the most recent study, researchers at the University at Albany looked at 1,438 patients with coronavirus who were admitted to 25 New York City area hospitals. After statistical adjustments, the death rate for patients taking hydroxychloroquine was similar to those who did not take the drug. The death rate for those taking hydroxychloroquine plus the antibiotic azithromycin, was also similar.
However, the patients who took the drug combination were more than twice as likely to suffer cardiac arrest during the course of the study. Heart issues are a known side effect of hydroxychloroquine ...
https://www.kvor.com/news/yet-another-study-shows-hydroxychloroquine-doesnt-work-against-covid-19/
struggle4progress
(118,236 posts)Lydia Ramsey
13 hours ago
... In NEJM, an observational study looked at 1,376 patients admitted to Columbia University Irving Medical Center in New York City, 811 of who were given hydroxychloroquine. It found that administering hydroxychloroquine was not associated with an increased or lowered risk of intubation or death compared to those who didn't receive hydroxychloroquine.
The patients who received hydroxychloroquine tended to be more severely ill than those who did not receive the drug. Authors of both studies noted that randomized controlled trials which assign patients either to the medication or a placebo control at random are needed ...
https://www.businessinsider.com/jama-nejm-studies-on-hydroxychloroquine-for-coronavirus-patients-2020-5
SunSeeker
(51,520 posts)struggle4progress
(118,236 posts)By Daniel Israel - May 11, 2020
... Dr. Tucker Woods, Chief Medical Officer at Christ Hospital in Jersey City, said that Hydroxychloroquine is no longer used for the most part, in favor of more promising treatments ...
After some studies that were published here in the United States, now I think its lost a lot of its initial hopes.
Dr. Nizar Kifaieh struck a similar tone at Hudson Regional Hospital in Secaucus ...
https://hudsonreporter.com/2020/05/11/hydroxychloroquine-falls-out-of-use-in-hudson-county/
struggle4progress
(118,236 posts)By Michael O'Keeffe
Updated May 10, 2020 7:31 PM
Sen. Chuck Schumer asked the Department of Veterans Affairs on Sunday to explain why it continues to use hydroxychloroquine to treat patients with the coronavirus, saying the anti-malaria drug is not only ineffective in treating COVID-19 but has also been linked to life-threatening cardiac arrests.
Schumer (D-N.Y.) also demanded to know why the agency recently spent $208,000 for a bulk purchase of hydroxychloroquine, which President Donald Trump and his allies have pushed, without scientific evidence, as a treatment for the coronavirus.
The Senate minority leader questioned whether veterans have been clandestinely given the drug ...
https://www.newsday.com/news/health/coronavirus/schumer-coronavirus-hydroxychloroquine-veterans-1.44535052
struggle4progress
(118,236 posts)ROGER SOLLENBERGER
MAY 9, 2020 1:55AM (UTC)
Fox News host Laura Ingraham, who has publicly acknowledged her lack of medical expertise, made a personal appeal to President Donald Trump on her broadcast to "pull back" a "misguided" FDA warning about an unproven drug treatment for the new coronavirus.
"We now have multiple studies across the globe and reports from treating physicians regarding the safety and efficacy of hydroxychloroquine," Ingraham during a Wednesday segment. "Along with hundreds of thousands of lupus and rheumatoid arthritis patients who've been taking the drug for decades without complications. Time for the FDA the president himself to pull back on the misguided and unnecessary warning that was issued a few weeks ago" ...
https://www.salon.com/2020/05/08/hydroxychloroquine-truther-laura-ingraham-who-is-not-a-doctor-begs-trump-to-overturn-fdas-warning/
"I'm really a necrophiliac!"
struggle4progress
(118,236 posts)By Carla O'Day
May 8, 2020
Washoe County commissioners on Thursday rescinded a decision made last month that would ask the District Attorney to file a legal brief challenging a state decision that banned the use of certain drugs to treat COVID-19 patients outside a hospital setting ...
Commissioners decided April 21 to file an amicus brief supporting a challenge by the Nevada Osteopathic Medical Association to the Nevada State Board of Pharmacys emergency regulation banning the use of choloroquine and hydroxychloroquine to treat non-hospitalized coronavirus patients. An amicus brief is a document by a non-party to a lawsuit that is intended to outline legal arguments for the benefit of the court ...
https://thisisreno.com/2020/05/county-reverses-decision-to-file-amicus-brief-regarding-hydroxychloroquine-ban/
struggle4progress
(118,236 posts)By Emily Kopp and Thomas McKinless
Posted May 8, 2020 at 8:26am
The Strategic National Stockpile since April 1 has shipped to states 28 million tablets of a malaria drug that President Donald Trump touted as a potential treatment for COVID-19. States received millions more from donations or taxpayer-funded purchases.
But after doubts arose about whether the drug, hydroxychloroquine sulfate, is safe and effective for the coronavirus-based disease, states are donating supplies to patients who need them for other reasons, seeking refunds or weighing what to do with them ...
https://www.rollcall.com/2020/05/08/what-to-do-with-all-that-hydroxychloroquine-trump-touted/
littlemissmartypants
(22,593 posts)struggle4progress
(118,236 posts)May 06, 2020 12:03 PM IST
A fired American scientist has alleged that the Trump administration ignored the concern of doctors in the US over the importation of hydroxychloroquine from "uninspected factories" in India and Pakistan and flooded the country with the "unproven and potentially dangerous" anti-malarial drug.
In a complaint filed on Tuesday before the US Office of Special Counsel, which oversees the protection of whistleblowers, Rick Bright alleged that top officials of the Department of Health and Human Services (HHS) repeatedly ignored his messages and that of others over the Personal Protective Equipment (PPE) and medicines like hydroxychloroquine in particular ...
https://www.cnbctv18.com/politics/trump-admin-ignored-concern-over-hydroxychloroquine-import-from-in-india-pak-fired-us-scientist-5854801.htm
struggle4progress
(118,236 posts)By Anna Edney
May 5, 2020, 4:28 PM EDT
... as quickly as pharmacies were drained of the pills, the tide has now turned against hydroxychloroquine and its chemical cousin, chloroquine. Regulators and scientists have raised concerns about potentially serious side effects, while Gilead Sciences Inc.s antiviral therapy remdesivir was cleared for U.S. use. Some hospitals, including Mount Sinai Health System in New York, no longer include the drug in their treatment regimen for Covid-19.
The surge resulted in shortages that left patients whod long taken the medication to treat lupus and rheumatoid arthritis hunting for alternatives. To help get more drugs to market, the Food and Drug Administration has allowed overseas manufacturing facilities that were previously sanctioned for quality violations to begin producing it for U.S. patients.
Hydroxychloroquine prescriptions jumped to 298,660 during the week of March 20, more than doubling from a week earlier, according to data compiled by Bloomberg Intelligence. But prescriptions have now plummeted back to nearly normal levels, and there are signs a speed-up in manufacturing is slowing ...
https://www.bloomberg.com/news/articles/2020-05-05/trump-s-virus-drug-whim-costs-millions-even-as-the-mania-wanes
jberryhill
(62,444 posts)https://forbetterscience.com/2020/04/22/chloroquine-witchdoctor-didier-raoult-barking-mad-and-dangerous/
This is why chloroquine proponents changed their stance and now scream that it is wrong to treat very sick COVID-19 patients with chloroquine. Instead, they insist that the drug must be given very early during infection or even prophylactically, i.e., to healthy and asymptomatic people only. Given the evidence that the coronavirus is apparently lethal for less than 1% of the infected, you can see where this is going. The safest way to successfully heal with witchdoctor magic is to treat those who are not really ill and recover anyway.
Cicada
(4,533 posts)A random assignment study is under way. That will be something we can rely on.
Snarkoleptic
(5,997 posts)tanyev
(42,522 posts)And hes always, always, always, always, always, always, always, always, always, always, always, always, always, always, always, always right.
jmg257
(11,996 posts)Its been criticized as unproven, but now a major hospital in New York is launching a clinical trial based on the treatment, reports CBS2s Carolyn Gusoff.
In the village of Kiryas Joel in Orange County, Dr. Vladimir Zelenko, a self-described country doctor, says a cocktail of medicines keeps his patients alive.
Weeks ago, he recorded this message for President Donald Trump: Im seeing tremendous positive results. I havent sent any patient to the hospital yet, even though Ive treated hundreds already.
https://newyork.cbslocal.com/2020/04/30/coronavirus-exclusive-meet-the-doctor-behind-the-hydroxychloroquine-treatment-for-covid-19/
Hydroxychloroquine got the presidents attention, and swiftly got him criticism for touting unfounded cures.
There are people dying, said Trump at the time. If it works, that would be great.
LisaL
(44,972 posts)Which is why unproven drugs aren't normally used to treat diseases before one has a clue if it helps or hurts.
jmg257
(11,996 posts)They have a had a big share of cases in the county...enough that Cuomo was asked to block off the area like he did in with new Rochell (he refused).
LisaL
(44,972 posts)Zinc actually has anti-viral properties so might do a little something.
spanone
(135,795 posts)LisaL
(44,972 posts)Some hospitals apparently are using it as a standard of care. When it seems to hurt (cardiovascular side effects) instead of helping.