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nitpicker

(7,153 posts)
Fri May 22, 2020, 08:51 AM May 2020

Coronavirus: Immune clue sparks treatment hope

https://www.bbc.com/news/health-52754280

Coronavirus: Immune clue sparks treatment hope

By Victoria Gill & Rachael Buchanan
BBC News

22 May 2020

UK scientists are to begin testing a treatment that it is hoped could counter the effects of Covid-19 in the most seriously ill patients.

It has been found those with the most severe form of the disease have extremely low numbers of an immune cell called a T-cell. T-cells clear infection from the body.

The clinical trial will evaluate if a drug called interleukin 7, known to boost T-cell numbers, can aid patients' recovery. It involves scientists from the Francis Crick Institute, King's College London and Guy's and St Thomas' Hospital.

They have looked at immune cells in the blood of 60 Covid-19 patients and found an apparent crash in the numbers of T-cells.
(snip)

The researchers say these findings pave the way for them to develop a "fingerprint test" to check the levels of T-cells in the blood which could provide early indications of who might go on to develop more severe disease.

But it also provides the possibility for a specific treatment to reverse that immune cell decline.
(snip)

In this trial, it will be given to patients with a low lymphocyte count who have been in critical care for more than three days.

Mr Shankar-Hari said: "We are hoping that [when we increase the cell count] the viral infections gets cleared.
(snip)



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Coronavirus: Immune clue sparks treatment hope (Original Post) nitpicker May 2020 OP
Great, but why wait until they're in critical care for 3 days? ecstatic May 2020 #1
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