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So, Moderna's vaccine is clearly superior. Will Pfizer even play a role in our recovery? (Original Post) Goodheart Nov 2020 OP
I would think both would be used. Happy Hoosier Nov 2020 #1
They're just working on getting the brain-controlling nanobots to be small enough. 🤣 TheBlackAdder Nov 2020 #25
HA! Happy Hoosier Nov 2020 #28
Given the production/distribution challenges, I suspect both would be used unblock Nov 2020 #2
Ford vs Chevrolet? Brother Buzz Nov 2020 #3
As long as it get's you where you need to go........ virus free... nt mitch96 Nov 2020 #13
But, but Pfizer's comes with a designer suitcase, so maybe it's really Ford v Ferrari Brother Buzz Nov 2020 #18
O000oooo I like the designer suit case... mitch96 Nov 2020 #21
I read Pfizer's can be manufactured more quickly, plus with their head start Alhena Nov 2020 #4
88% was already pre-ordered by other countries. Plus Pfizer's has refrigeration delivery issues. TheBlackAdder Nov 2020 #27
but is the efficacy the same or better? Native Nov 2020 #5
I don't trust Moderna Johnny2X2X Nov 2020 #6
And they have NEVER brought a vaccine to market Horse with no Name Nov 2020 #14
I'm glad that didn't stop them from trying. Steelrolled Nov 2020 #20
links on this (Kushner connections and the Moderna lying before) please TIA Celerity Nov 2020 #16
" closely aligned with Jared," ok something stinks right there... hard stop is right!! mitch96 Nov 2020 #22
I think Pfizer can have theirs out first. NutmegYankee Nov 2020 #7
Superior according to whom? It's a press release based on preliminary phase III trial data. nt Cognitive_Resonance Nov 2020 #8
Clearly superior? LisaL Nov 2020 #9
And both need to be stored at sub-zero temperatures N/T lapucelle Nov 2020 #10
No, the Moderna one can be refrigerated sir pball Nov 2020 #29
Yes, I saw that later. I had read (or misread) an earlier report lapucelle Nov 2020 #34
A few percent difference in the short-term efficacy is down in the noise. lagomorph777 Nov 2020 #11
Preliminary data. PoindexterOglethorpe Nov 2020 #12
No, not clearly superior. Both are 90%+ effective, based on MineralMan Nov 2020 #15
I think they are about the same Steelrolled Nov 2020 #17
This message was self-deleted by its author pinkstarburst Nov 2020 #19
Pfizer and Moderna Steelrolled Nov 2020 #24
Yep, Oxford uses more traditional adenovirus based technology. LisaL Nov 2020 #31
Don't think anything has been established as being "clearly superior" and both will be released lettucebe Nov 2020 #23
Exactly. LisaL Nov 2020 #30
Moderna's PRESS RELEASE is clearly superior. spanone Nov 2020 #26
Point taken. Goodheart Nov 2020 #32
That's all we got from Pfizer too. No peer review, no FDA review. spanone Nov 2020 #33

Happy Hoosier

(7,216 posts)
1. I would think both would be used.
Mon Nov 16, 2020, 12:24 PM
Nov 2020

The goal is to vaccinate as many people as possible as quickly as possible.

Brother Buzz

(36,375 posts)
18. But, but Pfizer's comes with a designer suitcase, so maybe it's really Ford v Ferrari
Mon Nov 16, 2020, 01:52 PM
Nov 2020
Pfizer designed suitcase-sized shipping containers that will keep its doses at ultracold temperatures for up to 10 days. Each container holds between 1,000 and 5,000 doses, charged by dry ice. The shipping containers are reusable.



https://www.fiercepharma.com/manufacturing/pfizer-designed-new-container-and-plans-to-tap-shipping-companies-for-covid-19

Alhena

(3,030 posts)
4. I read Pfizer's can be manufactured more quickly, plus with their head start
Mon Nov 16, 2020, 12:29 PM
Nov 2020

that means they should be first.

Johnny2X2X

(18,969 posts)
6. I don't trust Moderna
Mon Nov 16, 2020, 12:31 PM
Nov 2020

This is a company closely aligned with Jared, they've been exposed for lying before.

mitch96

(13,870 posts)
22. " closely aligned with Jared," ok something stinks right there... hard stop is right!!
Mon Nov 16, 2020, 01:58 PM
Nov 2020

Follow the money and the science... Has not failed me yet...
YMMV
m

sir pball

(4,737 posts)
29. No, the Moderna one can be refrigerated
Mon Nov 16, 2020, 02:26 PM
Nov 2020

It has an acceptable shelf life (2 weeks I think) at 36-46F. It lasts a lot longer at 4F, but that's still normal home freezer temperatures, the existing cold storage and distribution infrastructure is perfectly fine for those constraints.

lapucelle

(18,187 posts)
34. Yes, I saw that later. I had read (or misread) an earlier report
Mon Nov 16, 2020, 07:50 PM
Nov 2020

that the it needed the lower temperature.

Thank you for the update!


lagomorph777

(30,613 posts)
11. A few percent difference in the short-term efficacy is down in the noise.
Mon Nov 16, 2020, 12:51 PM
Nov 2020

A repeat of the studies with identical methods and larger samples would just as likely reverse the apparent result.

Other factors will be more important:

Ability to ramp up
Difficulty of storage and transport
Cost
Political factors
etc

PoindexterOglethorpe

(25,816 posts)
12. Preliminary data.
Mon Nov 16, 2020, 01:36 PM
Nov 2020

That does not comfort me.

How many times have we seen early reports about some "promising" new medication that should cure, say, Alzheimer's forever, only to learn it simply doesn't have any impact on the disease in humans.

Yeah, I know these are clinical trials in humans, but then again, how many "promising" early clinical trials have turned out to be duds?

MineralMan

(146,254 posts)
15. No, not clearly superior. Both are 90%+ effective, based on
Mon Nov 16, 2020, 01:45 PM
Nov 2020

preliminary trial results. That's a very high effectiveness rate for any vaccine.

So, both will probably be distributed and used. I'll take whichever one is available as soon as I can.

 

Steelrolled

(2,022 posts)
17. I think they are about the same
Mon Nov 16, 2020, 01:52 PM
Nov 2020

based on what we know so far. I think the deciding factor will be who can make it the fastest.

Response to Goodheart (Original post)

 

Steelrolled

(2,022 posts)
24. Pfizer and Moderna
Mon Nov 16, 2020, 02:01 PM
Nov 2020

use the same technology. The Oxford vaccine uses a different technology, but we don't have numbers for it yet.

LisaL

(44,972 posts)
31. Yep, Oxford uses more traditional adenovirus based technology.
Mon Nov 16, 2020, 02:29 PM
Nov 2020

Moderna and Pfizer are both RNA based vaccines.

lettucebe

(2,336 posts)
23. Don't think anything has been established as being "clearly superior" and both will be released
Mon Nov 16, 2020, 01:59 PM
Nov 2020

Whatever vaccine by whichever company makes it to your local pharmacy, that's the one you'll get. These are all preliminary results at this point. It'll be a few years before we know the real truth. They don't even know how long the vaccine will last as of yet. Give it time.

LisaL

(44,972 posts)
30. Exactly.
Mon Nov 16, 2020, 02:28 PM
Nov 2020

Each company can make limited doses initially. Not enough to vaccinate the whole population.
So I am assuming whichever one your local places can get their hands on will be available initially.

spanone

(135,791 posts)
33. That's all we got from Pfizer too. No peer review, no FDA review.
Mon Nov 16, 2020, 02:54 PM
Nov 2020

sure gives their stocks a boost.



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