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MindMover

(5,016 posts)
Thu May 17, 2012, 08:48 PM May 2012

Pill to stay sober

Last edited Fri May 18, 2012, 01:50 AM - Edit history (1)

DOCTORS are testing a drug that could stop alcohol making people drunk.The researchers believe iomazenil, taken before drinking, might negate some of alcohol's effects on the brain. Tests in a driving simulator will determine whether the drug makes volunteer drinkers safer behind the wheel after imbibing.

The results of a pilot study suggest those who take iomazenil before drinking brake more quickly. Researchers from Yale University hope iomazenil could help in developing a stay-sober pill to wean heavy drinkers off alcohol. Researcher Deepak DSouza, a psychiatrist, said: "A medication that has the potential to block alcohol actions in the central nervous system could act as a unique medication in the treatment of alcohol intoxication and alcoholism." "Alcohol is abused commonly but there is no remedy for alcohol intoxication."

This project is looking at the substance iomazenil and its effect on alcohol intoxication and alcohols effects on driving an automobile. He is far from the only researcher trying to find a way to take some of the harm out of drinking. In other recent work on a potential stay sober pill, mice given a drug didn't get drunk, despite being given enough booze to make them stumble and fall. It is hoped the drug, naloxone, a chemical cousin of a drug already used to save heroin addicts from overdose, will be given to people for the first time within 18 months.

However, the treatment is also likely to take the pleasure out of boozing. So while you might be able to tolerate booze better, you wouldnt feel like drinking in the first place. It is also unlikely that a stay-sober pill would protect other organs, such as the liver, from damage. A third option could be harm-free alcohol. British researchers are trying to develop liquid drugs that give all the pleasure of alcohol but without any of the harm. The Valium-like pharmaceutical shots would mimic the pleasant buzz of alcohol without leading to drunkenness.


More: http://www.dailytelegraph.com.au/lifestyle/pill-to-stay-sober/story-e6frf00i-1226355216631

28 replies = new reply since forum marked as read
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Pill to stay sober (Original Post) MindMover May 2012 OP
So in other words it takes away the only positives of drinking alcohol. TheWraith May 2012 #1
This message was self-deleted by its author Warren DeMontague May 2012 #2
Don't drink,you won't get drunk. Simple. virgogal May 2012 #3
It would be great if they develop a pill that keeps alcohol from causing physical harm lunatica May 2012 #4
There is a remedy for alcohol intoxication. MrSlayer May 2012 #5
There is also a remedy for cocaine intoxication. madinmaryland May 2012 #7
Indeed. MrSlayer May 2012 #12
There's a remedy for marijuana highs longship May 2012 #15
No. It's called potato chips!! madinmaryland May 2012 #24
This message was self-deleted by its author Warren DeMontague May 2012 #22
Heh. MrSlayer May 2012 #26
WTF? JanetLovesObama May 2012 #6
Uh yeah... SammyWinstonJack May 2012 #8
That's what I think too. Even if they did develop "Valium=like pharmaceutical shots" the US RKP5637 May 2012 #11
I don't get high anymore.. Whiskeytide May 2012 #19
Yep! There's a lot more to it than this ridiculous pious moralizing RKP5637 May 2012 #23
I am so not the host here XemaSab May 2012 #9
So now the only point is to destroy your liver? Ruby the Liberal May 2012 #10
Right. MrSlayer May 2012 #13
Exactly! I think people well might be inclined to drink and drink, maybe RKP5637 May 2012 #14
Why spoil it? longship May 2012 #16
sounds like not drinking would be the ideal solution spanone May 2012 #17
Yeah, I remember that scene from Revenge of the Nerds. sadbear May 2012 #18
LSD does that too. dionysus May 2012 #20
There is already a free solution ... don't drink or at least drink in moderation. nt Raine May 2012 #21
I want no part of that pill. Zax2me May 2012 #25
well, that pill is certainly not for me, but I can see why it might appeal to someone who fishwax May 2012 #27
that's what coke is for. n/t taught_me_patience May 2012 #28

Response to MindMover (Original post)

lunatica

(53,410 posts)
4. It would be great if they develop a pill that keeps alcohol from causing physical harm
Thu May 17, 2012, 09:01 PM
May 2012

Or a pill that lets people drunk and an antidote to sober up quickly.

This is very promising.

Response to MrSlayer (Reply #5)

 

JanetLovesObama

(548 posts)
6. WTF?
Thu May 17, 2012, 09:04 PM
May 2012

Why would anyone in their right mind (maybe that is the key) want to ingest enough alcohol to gain weight but not have the option of getting drunk ? Makes no sense !

SammyWinstonJack

(44,130 posts)
8. Uh yeah...
Thu May 17, 2012, 09:13 PM
May 2012
Valium=like pharmaceutical shots would mimic the pleasant buzz of alcohol without leading to drunkness.


Legalize weed...no need for this pill.

RKP5637

(67,101 posts)
11. That's what I think too. Even if they did develop "Valium=like pharmaceutical shots" the US
Thu May 17, 2012, 09:33 PM
May 2012

would never legalize it, probably. There seems to be a thing in the US that it's OK to drink your guts out and do hard drugs, but weed, on no, that's bad. All my life they've been trying to discredit weed and make it out to be a horrific drug, but no real success, and they still try.

Meanwhile, apparently, the US gov. feels all of the murders, the senseless deaths, crime from marijuana prohibition laws are perfectly fine.

Often I think a lot of it has to do with protecting the jobs of enforcers and also the tremendous profits being made by keeping marijuana illegal.

Whiskeytide

(4,461 posts)
19. I don't get high anymore..
Thu May 17, 2012, 10:41 PM
May 2012

... but I have come to believe the pharm industry promotes the war on weed because its too easy to grow yourself in your backyard. They can't allow a popular and legal drug that they can't profit from.

RKP5637

(67,101 posts)
23. Yep! There's a lot more to it than this ridiculous pious moralizing
Thu May 17, 2012, 10:55 PM
May 2012

that goes on about the evils of marijuana. It's all BS. Tremendous profits are made by some, and as you say, and I agree, the pharm industry wants the profits they will make as a prescription drug. People do not enter into the equation at all, it's all about pharm $$$.

Ruby the Liberal

(26,219 posts)
10. So now the only point is to destroy your liver?
Thu May 17, 2012, 09:14 PM
May 2012

I don't see how this is going to help with alcoholism. May even make people drink more.

RKP5637

(67,101 posts)
14. Exactly! I think people well might be inclined to drink and drink, maybe
Thu May 17, 2012, 09:40 PM
May 2012

even unconsciously, to try to get high. And, if you get no buzz from drinking, why even bother. It's kind of a weird convolution.

fishwax

(29,149 posts)
27. well, that pill is certainly not for me, but I can see why it might appeal to someone who
Fri May 18, 2012, 12:31 AM
May 2012

is interested in quitting drinking and having a difficult time of it. As so many have already posted, if you aren't getting buzzed/drunk, there is much less point in drinking in the first place. I'm sure it wouldn't be effective for everyone, though, and could be dangerous if people drink more to chase the feeling.

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