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forest444

(5,902 posts)
Sat Jan 30, 2016, 12:25 PM Jan 2016

Zika outbreak epicenter in same area where Oxitec GM mosquitoes were released in 2015

Zika seemingly exploded out of nowhere. Though it was first discovered in 1947, cases only sporadically occurred throughout Africa and southern Asia. In 2007, the first case was reported in the Pacific. In 2013, a smattering of small outbreaks and individual cases were officially documented in Africa and the western Pacific. They also began showing up in the Americas. In May 2015, Brazil reported its first case of Zika virus — and the situation changed dramatically.

Enter Oxitec, a British company recently purchased by Intrexon, a synthetic biology company based in Maryland. Oxitec first unveiled its large-scale, genetically-modified mosquito farm in Juazeiro, in Northeast Brazil, in July 2012, with the goal of reducing “the incidence of dengue fever,” The Disease Daily reported. By July 2015, shortly after the GM mosquitoes were first released into the wild in Juazeiro, Oxitec proudly announced they had “successfully controlled the Aedes aegypti mosquito that spreads dengue fever, chikungunya and zika virus, by reducing the target population by more than 90%.”

Northeast Brazil is now considered the epicenter of the Zika outbreak, which coincides with at least 4,000 reports of babies born with microcephaly just since October. Half of the workforce of the mining sector in the region is comprised of children. Without viable economic alternatives, most children must join their parents in rudimentary mining pits; children as young as two years transport, wash, and crush minerals to earn half a dollar a day.

The particular strain of Oxitec GM mosquitoes, OX513A, are genetically altered so the vast majority of their offspring will die before they mature — though Dr. Ricarda Steinbrecher published concerns in a report in September 2010 that a known survival rate of 3-4 % warranted further study before the release of the GM insects. Her concerns, which were echoed by several other scientists both at the time and since, appear to have been ignored — though they should not have been.

Those genetically-modified mosquitoes work to control wild, potentially disease-carrying populations in a very specific manner. Only the male modified Aedes mosquitoes are supposed to be released into the wild — as they will mate with their unaltered female counterparts. Once offspring are produced, the modified, scientific facet is supposed to ‘kick in’ and kill that larvae before it reaches breeding age — if tetracycline is not present during its development. But there is a problem: as a confidential internal Oxitec document divulged in 2012, that survival rate could be as high as 15% — even with low levels of tetracycline present.

Even absent this tetracycline, as Steinbrecher explained, a “sub-population” of genetically-modified Aedes mosquitoes could theoretically develop and thrive, in theory, “capable of surviving and flourishing despite any further” releases of ‘pure’ GM mosquitoes which still have that gene intact. She added, “the effectiveness of the system also depends on the [genetically-designed] late onset of the lethality. If the time of onset is altered due to environmental conditions … then a 3-4% [survival rate] represents a much bigger problem.”

As the WHO stated in its press release, “conditions associated with this year’s El Niño weather pattern are expected to increase mosquito populations greatly in many areas.”

At: http://www.healthfreedoms.org/zika-outbreak-epicenter-in-same-area-where-gm-mosquitoes-were-released-in-2015/

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Zika outbreak epicenter in same area where Oxitec GM mosquitoes were released in 2015 (Original Post) forest444 Jan 2016 OP
That's encouraging. Donald Ian Rankin Jan 2016 #1
That's how I read it too. yardwork Jan 2016 #14
Hubris? Intrexon Corporation (NYSE: XON) is Powering the Bioindustrial Revolution with Better DNA™ proverbialwisdom Jan 2016 #17
Err, that's backwards Recursion Jan 2016 #2
Would that it were so. forest444 Jan 2016 #4
No, it was *declared* after it Recursion Jan 2016 #5
The Juazeiro farm was in fact established in 2012. forest444 Jan 2016 #7
To be fair - the release site was chosen because it was already infested with mosquitoes. hedgehog Jan 2016 #3
I'll say. forest444 Jan 2016 #6
Our "scientists" are really so corrupted by the BIg corporation's nd their truedelphi Jan 2016 #26
That source is suspect. It includes the PP lie about selling baby parts--and that BS is *still* tblue37 Jan 2016 #8
To wit: forest444 Jan 2016 #9
Not following what the GM mosquitos have to do with Zika. NutmegYankee Jan 2016 #10
They're referring to this particular strain of Zika. forest444 Jan 2016 #11
Still not following what a failed mosquito control effort has to do with it. NutmegYankee Jan 2016 #12
"Has not yet succeeded after less than a year" does not equal "failed". Donald Ian Rankin Jan 2016 #16
And originated in the Pacific. Igel Jan 2016 #13
I did read 1939 Jan 2016 #23
Not surprised. Faux pas Jan 2016 #15
Explain HOW a sterile mosquito strain created a more dangerous strain of virus to emerge? NickB79 Jan 2016 #18
Wait, wait, isn't rushing to judgement ahead of the science to be discouraged? proverbialwisdom Jan 2016 #27
Wait, so... they made mosquitos that could go back in time? Lancero Jan 2016 #19
That article is based on fiction. alp227 Jan 2016 #21
Yes this is true malaise Jan 2016 #20
Oryx and Crake. nt Zorra Jan 2016 #22
Woo-woo anti-GMO, anti-science conspiracy bullshit. Odin2005 Jan 2016 #24
The virus carrying mossies were in Africa Boudica the Lyoness Jan 2016 #25
healthfreedoms.org LOL...nt SidDithers Jan 2016 #28
Mosquito-borne illnesses are likely in places where mosquitoes are prevalent petronius Jan 2016 #29

Donald Ian Rankin

(13,598 posts)
1. That's encouraging.
Sat Jan 30, 2016, 12:30 PM
Jan 2016

Although this sloppily-written piece of innuendo clearly wants the reader to come away thinking that the release of GM mosquitos is part of the problem, despite only having happened last year, what this actually means is that there are measures already underway that may, in a few more years time, help bring the problem under control.

proverbialwisdom

(4,959 posts)
17. Hubris? Intrexon Corporation (NYSE: XON) is Powering the Bioindustrial Revolution with Better DNA™
Sat Jan 30, 2016, 03:04 PM
Jan 2016

Better trust or think fast: http://www.oxitec.com/health/florida-keys-project/

http://www.oxitec.com/who-we-are/our-pipeline/

Our pipeline

Oxitec has a pipeline of products designed to combat insect pests of public health, animal health and agriculture.

Oxitec does basic research and creates product candidates at its laboratories in the UK. Optimised candidates are evaluated and tested in laboratory and field settings in conjunction with partners.

http://www.oxitec.com/press-release-intrexon-to-acquire-oxitec-pioneer-of-innovative-insect-control-solutions-addressing-global-challenges/

Press Release: Intrexon to acquire Oxitec, pioneer of innovative insect control solutions addressing global challenges
Germantown, MD, and Oxford, England, August 10, 2015

http://investors.dna.com/2016-01-05-Intrexon-to-Present-at-the-34th-Annual-J-P-Morgan-Healthcare-Conference

About Intrexon Corporation

Intrexon Corporation (NYSE: XON) is Powering the Bioindustrial Revolution with Better DNA™ to create biologically-based products that improve the quality of life and the health of the planet. The Company's integrated technology suite provides its partners across diverse markets with industrial-scale design and development of complex biological systems delivering unprecedented control, quality, function, and performance of living cells. We call our synthetic biology approach Better DNA®, and we invite you to discover more at http://www.dna.com/


http://www.democraticunderground.com/122844867
Justin Timberlake: What Goes Around Comes Around

forest444

(5,902 posts)
4. Would that it were so.
Sat Jan 30, 2016, 12:39 PM
Jan 2016

But the ongoing outbreak of this particular strain of nearly-incurable Zika virus occurred immediately after these Oxitec mosquitoes were released in July 2015.

forest444

(5,902 posts)
7. The Juazeiro farm was in fact established in 2012.
Sat Jan 30, 2016, 12:42 PM
Jan 2016

It's more than likely that some escaped even before their official, 2015 release.

hedgehog

(36,286 posts)
3. To be fair - the release site was chosen because it was already infested with mosquitoes.
Sat Jan 30, 2016, 12:34 PM
Jan 2016

What happened to the method of releasing sterilized males?

forest444

(5,902 posts)
6. I'll say.
Sat Jan 30, 2016, 12:40 PM
Jan 2016

Oxitec tried to create a killer mosquito with a very limited lifespan - but of course Mother Nature had other ideas.

That's why the ongoing outbreak of this particular strain of nearly-incurable Zika virus occurred immediately after these Oxitec mosquitoes were released in July 2015.

truedelphi

(32,324 posts)
26. Our "scientists" are really so corrupted by the BIg corporation's nd their
Sat Jan 30, 2016, 05:43 PM
Jan 2016

Big pockets blinding the scientists to what they are doing.

The GM crowd is fond of saying that no one has lost their life or been made sick by the purposeful creation of GM material.

But even that statement is wrong.

When the L Tryptophan produced in Japan and that had elements included in it from Gm cultivation methods, over 37 people died. (In the 1980's, nutritional supplements of L-tryptohan were taken off the market in the United States at one point due to some being linked to the disability disease eosinophilia-myalgia syndrome (EMS). )

tblue37

(65,216 posts)
8. That source is suspect. It includes the PP lie about selling baby parts--and that BS is *still*
Sat Jan 30, 2016, 12:46 PM
Jan 2016

being prominently displayed on that site. That by itself makes me suspicious of any information the site provides without its being backed up with info from more trustworthy sites.

forest444

(5,902 posts)
9. To wit:
Sat Jan 30, 2016, 12:50 PM
Jan 2016
Oxitec first unveiled its large-scale, genetically-modified mosquito farm in Juazeiro, in Northeast Brazil, in July 2012, with the goal of reducing “the incidence of dengue fever,” The Disease Daily reported.

By July 2015, shortly after the GM mosquitoes were first released into the wild in Juazeiro, Oxitec proudly announced they had “successfully controlled the Aedes aegypti mosquito that spreads dengue fever, chikungunya and zika virus, by reducing the target population by more than 90%.”


The Disease Daily reported...Oxitec announced (and proudly, no less). We can argue causality or lack thereof; but this definitely happened.

NutmegYankee

(16,199 posts)
10. Not following what the GM mosquitos have to do with Zika.
Sat Jan 30, 2016, 12:57 PM
Jan 2016

Zika has been around for at least 60 years, only being notable now that it has caught on in the Americas with more people to infect.

forest444

(5,902 posts)
11. They're referring to this particular strain of Zika.
Sat Jan 30, 2016, 01:01 PM
Jan 2016

Which, as we now know, has proven to be especially dangerous.

NutmegYankee

(16,199 posts)
12. Still not following what a failed mosquito control effort has to do with it.
Sat Jan 30, 2016, 01:13 PM
Jan 2016

We know where the virus came from. It was tracked moving East from Polynesia for years.

Donald Ian Rankin

(13,598 posts)
16. "Has not yet succeeded after less than a year" does not equal "failed".
Sat Jan 30, 2016, 02:24 PM
Jan 2016

The mosquitos were only released last year. Whether it works or not remains to be seen.

Igel

(35,270 posts)
13. And originated in the Pacific.
Sat Jan 30, 2016, 01:16 PM
Jan 2016

Done. Dusted.

Sure, somebody will claim that nobody noticed this strain in between its initial outbreak in the Pacific and the spread a few years later. Arguments from silence are typically faith-based and result in a lot of unpleasant screeching and huffing about.

'Nuff said, more's too much.

NickB79

(19,224 posts)
18. Explain HOW a sterile mosquito strain created a more dangerous strain of virus to emerge?
Sat Jan 30, 2016, 03:24 PM
Jan 2016

There is no biological explanation for how this would occur. GM organisms aren't some mix of mutagenic toxins that convert anything they touch into monsters.

The more likely explanation is that people of the Americas are more susceptible genetically to this strain of Zika than those in Asia or Africa, where it's been endemic for generations. As we've seen for the past 500 years, Old World diseases that were not exceedingly lethal to Europeans have played havoc with those of Native American descent.

proverbialwisdom

(4,959 posts)
27. Wait, wait, isn't rushing to judgement ahead of the science to be discouraged?
Sat Jan 30, 2016, 05:46 PM
Jan 2016


Jan. 28, 2016 | Charlie Rose
Excerpt (1:01 min) - Dr. Fauci on the likelihood of Zika's spread


Dr. Anthony Fauci answers "the critical question" regarding the Zika virus.

http://www.charlierose.com/
http://www.hulu.com/watch/899423

FULL SHOW VIDEO - Air Date 1/27/2016

ESSENTIAL VIEWING: Dr. Anthony Fauci interview between minutes 16:03 - 27:00


A preview of Super Bowl 50 with Bill Cowher, studio analyst for the “The NFL Today.” Dr. Anthony Fauci on the mosquito-borne Zika virus. “Fighting ISIS,” a new special report from Vice on HBO. Charlie is joined by the correspondent, Ben Anderson.



MORE: http://www.democraticunderground.com/?com=view_post&forum=1002&pid=7572685

http://www.theguardian.com/world/2016/jan/26/brazil-zika-virus-health-minister-armed-forces-eradication

...The WHO’s Lindmeier said on Tuesday that the organisation suspects a link between Zika and microcephaly, but cautioned that the evidence is circumstantial.

http://www.who.int/mediacentre/factsheets/zika/en/

...During large outbreaks in French Polynesia and Brazil in 2013 and 2015 respectively, national health authorities reported potential neurological and auto-immune complications of Zika virus disease. Recently in Brazil, local health authorities have observed an increase in Zika virus infections in the general public as well as an increase in babies born with microcephaly in northeast Brazil. Agencies investigating the Zika outbreaks are finding an increasing body of evidence about the link between Zika virus and microcephaly. However, more investigation is needed before we understand the relationship between microcephaly in babies and the Zika virus. Other potential causes are also being investigated.

And what might those unnamed "other potential causes" be? These questions are currently being examined. Aside: TIMING MATTERS.

Lancero

(3,002 posts)
19. Wait, so... they made mosquitos that could go back in time?
Sat Jan 30, 2016, 03:47 PM
Jan 2016

The mosquitos weren't released until July, yet the first major Zika outbreak was in May...

The 07 Zika outbreak in the Yap Islands is another 'lolno' to the theory that GM mosquitos was what caused the Zika virus to suddenly start popping up in other countries. (In fact, after the 07 outbreak health officials actually gave warning about the risks of Zika starting to appear in other countries)

Looks like the same strawgrasping we see from the antivaxxers really.

The other articles at the site are intresting though - Especially this one - http://www.healthfreedoms.org/murdered-holistic-doctors-had-discovered-autismcancer-causing-enzyme-intentionally-being-added-to-all-vaccines/

 

Boudica the Lyoness

(2,899 posts)
25. The virus carrying mossies were in Africa
Sat Jan 30, 2016, 05:21 PM
Jan 2016

Africans went to Brazil for the 2014 World Cup in June, and that's how it got to Brazil.

petronius

(26,595 posts)
29. Mosquito-borne illnesses are likely in places where mosquitoes are prevalent
Sat Jan 30, 2016, 05:55 PM
Jan 2016

Mosquito-control efforts are focused in areas where mosquitoes and mosquito-borne illnesses are present.

Mosquito-control efforts are unlikely to be perfect.

None of that adds up to "...the effort to control dengue, zika, and other viruses, appears to have backfired dramatically."

If this article is attempting to make an argument that the GM mosquitoes contributed to the spread of zika, that argument is flawed to the point of not being an argument at all...

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