Moderna's Covid-19 vaccine protects against Delta variant, study finds

[left-of-center2012]

Source: CNN

Moderna's Covid-19 vaccine protects people for at least six months and likely longer -- even against new variants, researchers reported Thursday.

Protection against the Delta variant, now dominant across the US, barely waned, the National Institutes of Health-led team found. The team will continue to look for evidence of protection beyond six months.

"High levels of binding antibodies recognizing all tested variants, including B.1.351 (Beta) and B.1.617.2 (Delta), were maintained in all subjects over this time period," immunologist Nicole Doria-Rose and colleagues at the NIH's National Institute of Allergy and Infectious Diseases wrote in their report, published in the journal Science.

"At the peak of response to the second vaccine dose, all individuals had responses to all variants," the team wrote. Two weeks after the second dose of Moderna's vaccine, all the blood samples neutralized all of the variants, they found.

Read more: https://www.cnn.com/2021/08/12/health/moderna-vaccine-protection/index.html

---

They included all the most common or worrying variants in the test: B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma), B.1.429 (Epsilon), B.1.526 (Iota) and B.1.617.2 (Delta).

[Moebym]

1. Oh, good

I have been fully vaccinated since April with the Moderna vaccine. The 'rents got Pfizer.

If a booster shot is needed, I'll be the first in line.

[keopeli]

2. I'm good through October 21 at least. That's encouraging!

[Shanti Shanti Shanti]

13. I'm good till end of Sept, maybe Moderna has a booster in development that works even better!

I finished my Moderna #2 without any problems, just a slight fever for a day

[No Vested Interest]

3. Is there a decision on whether or not it's recommended to mix/change from one

Last edited Fri Aug 13, 2021, 03:38 PM - Edit history (1)

vaccine brand to another?
I.e. - Pfizer to Moderna, or vice versa?

We must be changing many times from one flu vaccine to another, because I've never heard or known which brand I've been given.

[BumRushDaShow]

5. NIH started up a small trial back on June 1st

https://www.nih.gov/news-events/news-releases/nih-clinical-trial-evaluating-mixed-covid-19-vaccine-schedules-begins

I saw last month where Univ. of Washington was still recruiting for it, so I don't expect to hear anything definitive until maybe late winter (to at least give about 6 months of eval) although they might intermittently report what they are seeing and give a go-ahead anyway, since the vaccines have pretty much been so effective and have been tolerated very well so far. At the moment (as of an appearance Fauci had yesterday), he recommended to just stick with the same brand for now.

Regarding comparison with the flu vaccines - those are utilizing a different component source and process to create them versus the mRNA vaccines. The closest to them might be the Janssen (J&J) or AstraZeneca vaccines, but even then, they are still not like a "traditional" vaccine that uses actual virus or viral fragments (weakened or dead) to generate an immune response.

So I think they just want to make sure to allow time to monitor mixed candidates given these vaccines are literally the first time such a technology has been used.

[lagomorph777]

9. Well, recent news seems to be indicating we don't need to worry about that yet.

The vaccines seem to be holding up pretty well. I do expect future variants to be worse though; eventually boosters will be needed.

[Deminpenn]

10. Saw a clip of an interveiw with Fauci saying it's not

recommended to get a different booster for the approved 3rd shot for the immunocompromised. That might specific to that group, though.

[No Vested Interest]

11. Thanks to the three respondents above.

Food for thought.
I won't be acting without proper guidance, anyway.

[Hortensis]

12. Someone today, Sanjay Gupta?, was asked and said the

recommendation was for the third to be the same as the first two because the research done so far was for that. However, he felt there were indications that another vaccine might conceivably broaden coverage and that it should be okay to get a second type.

I noticed because I'm immunocompromised and it affects me directly, but also because I wondered if someone in the risk management department was making a note to discuss this with him. Probably he has good support for that last statement though.

[BumRushDaShow]

4. Good news!

My 6 months post-2nd dose Moderna will be around the 3rd week of October.

Will be interesting to see how it is with Lambda (although that one is being majorly crowded out by Delta at the moment).

[IronLionZion]

6. Good, that's what I got

Team Dolly Parton!

[Paladin]

7. This Moderna recipient is damn glad to hear it. (nt)

[lagomorph777]

8. Wonderful!

Pfizer here, but obviously I want everybody who's been vaccinated to be well-protected.