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riversedge

(70,182 posts)
Tue Feb 23, 2021, 08:50 AM Feb 2021

Why We Can't Make Vaccine Doses Any Faster..There's not much even the Defense Production Act can do

Informative article --best to read all of it.



Why We Can’t Make Vaccine Doses Any Faster
President Biden has promised enough doses for all American adults by this summer. There’s not much even the Defense Production Act can do to deliver doses before then.



https://www.propublica.org/article/covid-vaccine-supply?utm_source=pocket-newtab


by Isaac Arnsdorf and Ryan Gabrielson Feb. 19, 5 a.m. EST......................


.............................

Vaccine supply chains are extremely specialized and sensitive, relying on expensive machinery, highly trained staff and finicky ingredients. Manufacturers have run into intermittent shortages of key materials, according to the U.S. Government Accountability Office; the combination of surging demand and workforce disruptions from the pandemic has caused delays of four to 12 weeks for items that used to ship within a week, much like what happened when consumers were sent scrambling for household staples like flour, chicken wings and toilet paper.



People often question why the administration can’t use the mighty Defense Production Act — which empowers the government to demand critical supplies before anyone else — to turbocharge production. But that law has its limits. Each time a manufacturer adds new equipment or a new raw materials supplier, they are required to run extensive tests to ensure the hardware or ingredients consistently work as intended, then submit data to the Food and Drug Administration. Adding capacity “doesn’t happen in a blink of an eye,” said Jennifer Pancorbo, director of industry programs and research at North Carolina State University’s Biomanufacturing Training and Education Center. “It takes a good chunk of weeks.”

And adding supplies at any one point only helps if production can be expanded up and down the entire chain. “Thousands of components may be needed,” said Gerald W. Parker, director of the Pandemic and Biosecurity Policy Program at Texas A&M University’s Scowcroft Institute for International Affairs and a former senior official in the Department of Health and Human Services office for preparedness and response. “You can’t just turn on the Defense Production Act and make it happen.”

The U.S. doesn’t have spare facilities waiting around to manufacture vaccines, or other kinds of factories that could be converted the way General Motors began producing ventilators last year. The GAO said the Army Corps of Engineers is helping to expand existing vaccine facilities, but it can’t be done overnight.


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Why We Can't Make Vaccine Doses Any Faster..There's not much even the Defense Production Act can do (Original Post) riversedge Feb 2021 OP
There is, however, the possibility of doubling the numbers FBaggins Feb 2021 #1
That we are trying, that we have a President that is not ignoring the patricia92243 Feb 2021 #2
Glad when everyone is vaccinated, but to be where we are roughly a year later is phenomenal. Hoyt Feb 2021 #3
The article isn't bad, but it misses some important points NNadir Feb 2021 #4
Someone should send that article Meghan McCain Seasider Feb 2021 #5
What about the machinery and processes used to produce vaccines for animals? LastLiberal in PalmSprings Feb 2021 #6
They should be about the same jmowreader Feb 2021 #7

FBaggins

(26,727 posts)
1. There is, however, the possibility of doubling the numbers
Tue Feb 23, 2021, 08:57 AM
Feb 2021

There is more and more indication that a single dose is about as effective as two. If that can be firmly established they can double the numbers virtually instantly

patricia92243

(12,595 posts)
2. That we are trying, that we have a President that is not ignoring the
Tue Feb 23, 2021, 09:08 AM
Feb 2021

problem and is giving everything he can to help us is assuring in its own way. Plus he is honoring the dead - another thing that is good for the nation.

The President should be the cheerleader-in-chief for the USA. President Biden is.

 

Hoyt

(54,770 posts)
3. Glad when everyone is vaccinated, but to be where we are roughly a year later is phenomenal.
Tue Feb 23, 2021, 09:54 AM
Feb 2021

The lost lives are a tragedy, of course, and many could have been saved without a Prez who failed to lead. But it's not just the USA with high numbers -- UK, France, Italy, and Spain are in a similar situation.

NNadir

(33,512 posts)
4. The article isn't bad, but it misses some important points
Tue Feb 23, 2021, 11:57 AM
Feb 2021

As a veteran of the rush to commercialized AIDS drugs, chiefly protease inhibitors, I think that most of these bottlenecks described will be addressed more quickly than people think.

Seasider

(169 posts)
5. Someone should send that article Meghan McCain
Tue Feb 23, 2021, 11:59 AM
Feb 2021

Who seems to think vaccines can be made and distributed overnight.

6. What about the machinery and processes used to produce vaccines for animals?
Tue Feb 23, 2021, 02:39 PM
Feb 2021

Could they be repurposed to increase the nation's supply? Or would the very idea turn people off, even if it were proven to be absolutely safe. If the FDA approved the vaccine as being identical to the Pfizer or Moderna vaccines, I would take it as opposed to going into the pandemic naked.

jmowreader

(50,550 posts)
7. They should be about the same
Wed Feb 24, 2021, 01:27 PM
Feb 2021

The big problem is getting the base stock for the vaccine. This isn’t a chemical process where you order precursor chemicals (or make them yourself in your own oil refinery) and stir them together. With vaccine you need to grow a batch of the infectious agent that you then perform various steps on to make the final product...and if it takes two weeks to get the virus to cooperate, that’s what it takes.

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