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Famous Faces of Alzheimer's (Original Post)
1monster
Sep 2015
OP
Elmer S. E. Dump
(5,751 posts)2. Yes. I feel the pain.
1monster
(11,012 posts)3. The good news!
http://www.sciencealert.com/new-alzheimer-s-treatment-fully-restores-memory-function
New Alzheimers treatment fully restores memory function
Of the mice that received the treatment, 75 percent got their memory function back.
Publishing in Science Translational Medicine, the team describes the technique as using a particular type of ultrasound called a focused therapeutic ultrasound, which non-invasively beams sound waves into the brain tissue. By oscillating super-fast, these sound waves are able to gently open up the blood-brain barrier, which is a layer that protects the brain against bacteria, and stimulate the brains microglial cells to activate. Microglila cells are basically waste-removal cells, so theyre able to clear out the toxic beta-amyloid clumps that are responsible for the worst symptoms of Alzheimers.
The team reports fully restoring the memory function of 75 percent of the mice they tested it on, with zero damage to the surrounding brain tissue. They found that the treated mice displayed improved performance in three memory tasks - a maze, a test to get them to recognise new objects, and one to get them to remember the places they should avoid.
"Were extremely excited by this innovation of treating Alzheimers without using drug therapeutics," one of the team, Jürgen Götz, said in a press release. "The word breakthrough is often misused, but in this case I think this really does fundamentally change our understanding of how to treat this disease, and I foresee a great future for this approach."
The team says theyre planning on starting trials with higher animal models, such as sheep, and hope to get their human trials underway in 2017.
New Alzheimers treatment fully restores memory function
Of the mice that received the treatment, 75 percent got their memory function back.
Publishing in Science Translational Medicine, the team describes the technique as using a particular type of ultrasound called a focused therapeutic ultrasound, which non-invasively beams sound waves into the brain tissue. By oscillating super-fast, these sound waves are able to gently open up the blood-brain barrier, which is a layer that protects the brain against bacteria, and stimulate the brains microglial cells to activate. Microglila cells are basically waste-removal cells, so theyre able to clear out the toxic beta-amyloid clumps that are responsible for the worst symptoms of Alzheimers.
The team reports fully restoring the memory function of 75 percent of the mice they tested it on, with zero damage to the surrounding brain tissue. They found that the treated mice displayed improved performance in three memory tasks - a maze, a test to get them to recognise new objects, and one to get them to remember the places they should avoid.
"Were extremely excited by this innovation of treating Alzheimers without using drug therapeutics," one of the team, Jürgen Götz, said in a press release. "The word breakthrough is often misused, but in this case I think this really does fundamentally change our understanding of how to treat this disease, and I foresee a great future for this approach."
The team says theyre planning on starting trials with higher animal models, such as sheep, and hope to get their human trials underway in 2017.
Elmer S. E. Dump
(5,751 posts)4. That is GREAT!!
rpannier
(24,284 posts)5. Sad. It's a great video
All those people that I grew up watching on TV or otherwise
I feel for people like Carroll Campbell Jr. Alzheimers in your 60s is cruel
I didn't know most of these people suffered/are still suffering from it
Dean Smith also had Alzheimers
My great uncle had it.
It's hard on everyone
The video is really touching
Thanks for sharing it and thanks to the person who made it