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n2doc

(47,953 posts)
Wed Dec 28, 2016, 11:36 AM Dec 2016

Once-promising diabetes breakthrough comes unglued with a major retraction

By DAMIAN GARDE @damiangarde

DECEMBER 27, 2016

One of the highest-profile researchers in diabetes has retracted a paper once heralded as a breakthrough, following multiple failed attempts to reproduce its headline-grabbing results.

The retraction ends three years of scrutiny into whether a discovery by Harvard University stem cell scientist Douglas Melton was indeed a major advance in the field of diabetes, with the paper’s authors now conclusively backing away from their earlier findings.

Back in 2013, Melton’s lab reported a promising discovery: A hormone found in the liver seemed to spur the production of insulin-producing cells in mice, lighting the way for a new approach to treating diabetes. The paper, published in the journal Cell, drew attention around the world, as it suggested a means of boosting insulin by using the body’s own machinery and held out the potential to free millions of diabetes patients from regular injections.

But the claim soon lost its luster.

more
https://www.statnews.com/2016/12/27/diabetes-breakthrough-retracted/

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Once-promising diabetes breakthrough comes unglued with a major retraction (Original Post) n2doc Dec 2016 OP
Damn TexasMommaWithAHat Dec 2016 #1
Trump's new FDA is gonna end all those pesky drug testing rules. dixiegrrrrl Dec 2016 #2

dixiegrrrrl

(60,010 posts)
2. Trump's new FDA is gonna end all those pesky drug testing rules.
Wed Dec 28, 2016, 01:22 PM
Dec 2016

Currently Big Pharma claims they can charge so much money because of all the drug testing required, including the gold standard of double blind human tests, and the standard that tests much be replicate-able.
Big Pharma has argued for releasing drugs more quickly ( and making huge bucks ) by allowing teh consumers to be the guinea pigs by self reporting any problems.

Some poor testing, or lack of testing is already known, by the numerous recalls of some drugs.
The lawsuits which led to the withdrawals won't happen in Turmp's FDA, tho, cause Big Pharma wants to supplant them by arbitration only options.

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