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intrepidity

intrepidity's Journal
intrepidity's Journal
March 17, 2020

Maybe we as a society come out the other end better off?

I've said this before, but this may really be a once in a multiple generation to have a societal paradigm shift, for the better. It's up to us

When vast swaths of Americans see that the world didn't end when they stepped off the treadmill for a few moments, when businesses realized they can adjust to having a substantial portion of their workforce telecommute, when millions finally see first hand the value of a strong public health policy and infrastructure, and that it's not "socialism" but sound social structure, maybe the scales start falling away from our collective eyes, the spell that the corporate and political class have hoodwinked us into trading our lives for starts to crack, when we experience again for more than a brief weekend what it's like to spend time with our families not on a hurried vacation but at home. Well, maybe we will all realize at once that things don't have to be the way we have allowed them to become. That we can slow it all down and if corporations have to settle for smaller profits, so be it.

Maybe we, those of us that make it, come out the other side with a renewed sense of how things could be. You won't get another chance like this.

Maybe?

March 17, 2020

Hey guys, just so you know when he said *it* was under control,

he meant their handling of the crisis. That was what was under control.

Now, aren't you ashamed of yourself for doubting him?

March 17, 2020

How long until Trump announces that

he's decided, with his big brain, that what this country really, really needs is a National Pandemic Response Team!

March 16, 2020

Hey RWNJs: Now would be the time to roll out those FEMA camps, doncha think??

Remind all your RW conspiracy nutjobs about this!

If not now, when?

March 16, 2020

We're building a system for the future, for if/when this happens again

"Mr. President: What would you say to the next president if you saw them dismantling the protections you are putting in place now?"

March 16, 2020

We broke the system on purpose!!!

OMG, the campaign ads write themselves

March 16, 2020

He wasn't tested!

The lying sack of shit!

March 16, 2020

The market needs to tank WHILE he's speaking

To stop this mofo from getting on stage at market close.

Thinks he's EF Hutton for crissakes

March 16, 2020

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

Full article at link below.

Abstract

Angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for SARS coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) that is causing the serious epidemic COVID-19. Here we present cryo-EM structures of full-length human ACE2, in the presence of a neutral amino acid transporter B0AT1, with or without the receptor binding domain (RBD) of the surface spike glycoprotein (S protein) of SARS-CoV-2, both at an overall resolution of 2.9 Å, with a local resolution of 3.5 Å at the ACE2-RBD interface. The ACE2-B0AT1 complex is assembled as a dimer of heterodimers, with the Collectrin-like domain (CLD) of ACE2 mediating homo-dimerization. The RBD is recognized by the extracellular peptidase domain (PD) of ACE2 mainly through polar residues. These findings provide important insights to the molecular basis for coronavirus recognition and infection.

https://science.sciencemag.org/content/early/2020/03/03/science.abb2762.full
March 14, 2020

I predict a dramatic decrease in deaths from the flu

All this hand-washing and other precautions to prevent Covid-19 will almost certainly result in a significant decrease in regular flu infections.

How could it not? Hopefully, the habits people acquire now will be sustained. We'll know the numbers by year end.

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Member since: Sun Feb 14, 2016, 07:36 PM
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