From Beagle Freedom Project's page:
"...Testing done on beagles in university and other research facilities includes medical/pharmaceutical, household products and cosmetics. When they are no longer wanted for research purposes, some labs attempt to find homes for adoptable, healthy beagles. Working directly with these labs, Beagle Freedom Project is able to remove and transport beagles to place them in loving homes. All rescues are done legally with the cooperation of the facility."
Also, they claim that 106,000 people die yearly from drugs tested safe on animals. I haven't checked further to determine if that is true or not.
For what it's worth, I was involved in human testing on a drug to treat cancer. It was a small study group with only about 40 of us participating. The goal was to determine a tolerable dosage level. The trial was to last 12 months. Within 3 months, nearly half had dropped out due to side effects. By the end there were only about a dozen of us left.
I developed severe bursitis in every major joint of my body, except the jaw area. I lasted the entire year, but the dose had to be lowered. It was a miserable year. The drug never made it to market.
I was able to relate how I felt to the researchers. I could have opted out at any time. These animals have no choice in the matter. It just makes me sad, that's all.