Reply #13: Was it known to feminize a prepubescient male, you mean? [View All]

[hlthe2b]

Well, theoretically long term use of any high dose form of estrogen could do so...


And, yes, prior to the mid 70s or so, the long term potential harm to daughters (and sons) whose mothers received DES while pregnant was not known and it really was considered a miracle drug. The risk for other cancer development was not known at the time. Hopefully your friend's daughter has escaped the risk. It was still considered somewhat miraculous for many years until, I think the late 90s-- for indications that excluded pregnancy.