A recent University of Northern Arizona study confirms depleted uranium as a heavy metal binds to DNA and causes genetic damage and mutations independent of its radiological effects.
Uranium - when manifested as a radioactive metal - has profound and debilitating effects on human DNA. These radioactive effects have been well understood for decades, but there has been considerable debate and little agreement concerning the possible health risks associated with low-grade uranium ore (yellowcake) and depleted uranium.
Now however, Northern Arizona University biochemist Diane Stearns has established that when cells are exposed to uranium, the uranium binds to DNA and the cells acquire mutations, triggering a whole slew of protein replication errors, some of which can lead to various cancers. Stearns' research, published in the journals Mutagenesis and Molecular Carcinogenesis, confirms what many have suspected for some time - that uranium can damage DNA as a heavy metal, independently of its radioactive properties. "Essentially, if you get a heavy metal stuck on DNA, you can get a mutation," Stearns explained. While other heavy metals are known to bind to DNA, Stearns and her team were the first to identify this characteristic with uranium.
http://www.scienceagogo.com/news/20060307010324data_trunc_sys.shtmlThe dust from the expended munitions is inhaled into the lungs and remain in the lungs or pass through the lung/blood barrier into the bloodstream.
Much of the ceramic DU aerosol is in respirable sized particles -10 micrometer and less in diameter. It stays in the lungs for upwards of two years. The uranium oxide, which was discussed in the Rand report, had a one-year half-life in lungs. Most natural uranium contamination in the human body comes via food and to a lesser extent from drinking water, not via the lungs. Ingested uranium is excreted in feces, basically never entering into the human blood and lymph system. In contrast, the DU ceramic aerosol released in war entered directly into lymph and blood through the lung-blood barrier and circulated throughout the whole body. All internal contamination is excreted through either sweat or urine.
DU is a very powerful alpha particle emitter, with each particle carrying a force of about 4.2 MeV (million electron volts). It requires only 6 to 10 eV (electron volts) to break the DNA or other large molecules in the body. This long stay of DU from weapons within the body can now be demonstrated through 24-hour urine analysis. The presence of DU eight years after the Gulf War exposure, means that the internal organs: lung, lymph glands, bone marrow, liver, kidney, and immune system have experienced significant localized radiation damage. Testing of urine for both veterans of the Gulf War and citizens of Iraq has confirmed this long-term exposure to DU.
Women (because of their radiation sensitive breast and uterine tissue) and children (because their bones are growing, thus able to pick up more DU than adults, and because they have a long expected life-span in which the cancers with long latency periods can develop) will be most at risk from the delayed DU weapon action.
SNIP
The more general conclusion, namely that the internal DU contamination of veterans, still evident eight years after their exposure in the Gulf War, is quite firm now. SNIP
Two points need to be stressed: veterans and civilians in these wars WERE exposed to DU; and this inhaled DU represents a seriously enhanced risk of damaged immune systems and fatal cancers. This type of radiological and chemical warfare should be banned.
http://www.iicph.org/docs/DU_Human_Rights_Tribunal.htm
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