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RamboLiberal Donating Member (1000+ posts) Send PM | Profile | Ignore Thu May-03-07 10:27 PM
Original message
Pet Food Poisoning Mystery May Be Solved
Edited on Thu May-03-07 10:37 PM by RamboLiberal
Source: CBS News

The mystery of how two chemicals that are considered non-toxic poisoned so many pets may have been solved, CBS News correspondent Nancy Cordes reports.

The breakthrough was made at the University of Guelph in Ontario, Canada. A week ago, scientist Perry Martos mixed together a few drops of melamine and cyanuric acid, the two unauthorized chemicals found in tainted pet food.

In less than a second, they formed a mass of crystals nearly identical to crystals found in the kidneys of sickened animals.

"If you can imagine an instantaneous kidney stone — that's essentially the way I would perceive it," says Martos

Read more: http://www.cbsnews.com/stories/2007/05/03/tech/main2758089.shtml



On edit adding this story from LA Times:

Reports say pet food death toll exceeds 8,000

Consumers have reported the deaths of as many as 8,500 dogs and cats as a result of tainted pet food, federal officials said Thursday.

In the two months since dead pets led to a massive U.S. pet food recall, the Food and Drug Administration said about half of the calls to its hotline were from owners of deceased cats and dogs.

Officials said the agency has not confirmed those reports, but added that the numbers of allegations likely will increase as it catches up with a backlog of calls reporting sick or dead animals.

http://www.latimes.com/business/la-fi-petfood4may04,0,4416256.story?coll=la-home-headlines
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youngdem Donating Member (1000+ posts) Send PM | Profile | Ignore Thu May-03-07 10:30 PM
Response to Original message
1. How horrible....I hope the responsible Chinese farmers eat a whole shitload of this stuff
Disgusting that profits are above all else.
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Cobalt Violet Donating Member (1000+ posts) Send PM | Profile | Ignore Thu May-03-07 10:33 PM
Response to Reply #1
2. They do have the death penalty for economic crimes over there.
They may end up losing their kidneys.
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thecrow Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 08:53 AM
Response to Reply #2
23. China detains head of gluten export company
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CountAllVotes Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 10:32 AM
Response to Reply #23
30. knowing China
he might not be around long enough to "testify" if such a thing is even allowed in China. :grr:

:argh:

:kick:

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TommyO Donating Member (1000+ posts) Send PM | Profile | Ignore Thu May-03-07 10:51 PM
Response to Reply #1
5. Include the greedy CEOs and you have a deal.
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cui bono Donating Member (1000+ posts) Send PM | Profile | Ignore Thu May-03-07 11:32 PM
Response to Reply #1
7. What about our politicians who voted in our trade/inspection policies?
What they do in China is horrible, but we should never have let things get to the point where this sort of thing is allowed into the US. Our trade policies, business practices and lack of inspections allowed it to come into this country.
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NewJeffCT Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 07:23 AM
Response to Reply #1
12. I doubt it was the farmers
It likely came from a much higher level from within the company/companies.
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NewJeffCT Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 07:23 AM
Response to Reply #1
13. I doubt it was the farmers
It likely came from a much higher level from within the company/companies.
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hippiechick Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 07:33 AM
Response to Reply #13
14. Tend to agree w/ you, NewJeff ....
n/t
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disndat Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 07:50 AM
Response to Reply #14
15. I agree with NewJeff too
More likely it is the Bush regime laissez-faire policies for big business and cutting down on FDA inspectors.
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NewJeffCT Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 08:22 AM
Response to Reply #15
17. It could be, but I would not be surprised
As I had posted on DU a few weeks back - competitor poisoning is not an uncommon form of "industrial espionage" in China. It could be, knowing that inspections/enforcement is lax both in China and the US, a competitor of this supplier managed to throw a monkey wrench into the works on a massive scale. That would not surprise me at all.

On a side not, I found out about this because I have in-laws in Nanjing, China and a few years back, I read a story online about 40+ people dying when a person poisoned the food in a competitor's restaurant in Nanjing. When I asked my sister-in-law about it, she said that 40+ was what the media reported, but it was likely more than that...
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marshall Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 10:45 AM
Response to Reply #1
31. One more reason to Buy American!
At least it's less likely to be poinsoned with all the regulations we have and "try" to follow.
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Javaman Donating Member (1000+ posts) Send PM | Profile | Ignore Thu May-03-07 10:42 PM
Response to Original message
3. I'm sure the military's chemical warfare division is watching this closely. nt
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Straight Shooter Donating Member (1000+ posts) Send PM | Profile | Ignore Thu May-03-07 10:43 PM
Response to Reply #3
4. Oh, thank you for that cheery scenario.
:P
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dipsydoodle Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 04:47 AM
Response to Reply #3
9. Perfectly sound observation
x(
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lovuian Donating Member (1000+ posts) Send PM | Profile | Ignore Thu May-03-07 10:52 PM
Response to Original message
6. They knew what they were doing Money Money Money
and you can't tell me the American company Menu food didn't know either
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diane in sf Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 12:13 AM
Response to Original message
8. The people responsible for this should be forced to donate one of their
kidneys to people in need! They could redeem themselves for pet murders by saving some human lives.

Sounds a little old Testament, but what the hey.
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livvy Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 05:44 AM
Response to Original message
10. Links to helpful sites and ASPCA Press Release 4/3/07
Here is a website that seems to have a good list of who gets their stuff from overseas and not…so far, it matches what I have seen others say.

http://www.thepetfoodlist.com/petfoods_pg1.htm

And here is the link to Itchmo's website. They are really doing a good job keeping up with this issue! Explore their site. There is lots of good stuff there!
http://www.itchmo.com/read/aspca-says-avoid-all-non-us-protein-supplements-crisis-not-over_20070503
Here is yesterday's press release from the ASPCA:

As Pet Food Recall Expands, ASPCA Warns Crisis Not Over: More Cases May Be Seen

Urges Veterinarians to Continue Aggressive Fluid Therapy to Treat Pet Food Recall Cases
ASPCA Media Contact

NEW YORK, May 3, 2007—With Menu Foods yesterday greatly expanding its recall of pet food products due to new evidence of cross-contamination, the ASPCA® (The American Society for the Prevention of Cruelty to Animals®) today warned pet parents that this crisis is far from over, and urged them to watch their pets closely for any symptoms that may be related to the recall.

“Given the fact that there is new evidence of cross-contamination in ingredients that may have been considered safe prior to this news, we need to be much more aware of where the ingredients in our pets’ food are coming from,” said Dr. Steven Hansen, a board-certified toxicologist and senior vice president with the ASPCA, who manages the ASPCA’s Animal Poison Control Center (APCC), located in its Midwest Office in Urbana, Ill.

“We are strongly recommending that pet parents immediately investigate, via their pet food manufacturer’s Web site or by calling them directly, where the ingredients—specifically protein supplements—are sourced from.”

Given the current situation and until this crisis is resolved, the ASPCA is recommending pets be fed products containing U. S.-sourced protein supplements only.

“The continued expansion of the recall is extremely worrying,” said Dr. Louise Murray, director of medicine at the ASPCA’s Bergh Memorial Animal Hospital (BMAH) in New York City, and a board-certified internist. “The magnitude of this crisis leaves us frustrated as to how to best protect pets and prevent any more illnesses or deaths.”

However, recent media reports that laboratory experiments on the interaction of melamine and cyanuric acid in cat urine showed the formation of crystals, are not surprising to ASPCA experts, and offer a glimmer of hope to veterinarians who have been worrying about how to save sick animals who have ingested the contaminated food.

“The fact that we have started to learn how the presence of melamine may be impacting these animals, gives us a small glimmer of hope—that at least we know we are on the right track when it comes to treating the animals affected,” said Dr. Hansen. “These findings really start putting everything else we have seen into perspective.”

In a study that was done several years ago on dogs and rats, the presence of melamine in their systems was found to only lead to the development of crystals in urine, but there were no further adverse effects—and nothing that showed a direct link between the chemical mechanism of melamine and the renal failure recently seen in the affected animals.

“Now that we see that crystals are formed when melamine and cyanuric acid are combined in cat urine, it may be that the cause of renal failure is somehow related to the obstruction caused by these crystals,” continued Dr. Hansen.

This also explains why animals whose symptoms were detected early enough, and who were rushed to their veterinarians and put on aggressive fluid therapy—as the ASPCA has been recommending—survived; since this treatment may help to prevent additional crystals from forming, and aid in flushing out the existing crystals from the animals’ urinary tracts, thus relieving the obstruction and reversing the effects of renal failure.

“Patience is the key,” said Dr. Murray, who has successfully treated several animals thus-affected with aggressive fluid therapy at BMAH. “We now understand that we have to bathe these crystals in fluid for as long as possible. With other causes of kidney failure, if there is no improvement in the animal’s condition after a day or two, the prognosis is usually not encouraging.

“In this case, however, when treating animals who have been sickened by eating the contaminated foods, longer-term intravenous fluids may be required —so we would strongly recommend that all veterinarians treating such cases be patient and continue administering fluids longer than they might otherwise, because they can really be life-saving.”

Unofficial estimates, including by those in the veterinary community, suggest the number of recall-related deaths may be in the thousands. The pet food recall crisis continues to unfold, with new developments appearing daily, and ramifications at the international trade, business and human health levels. As recently as yesterday, Menu Foods greatly expanded its recall list because of evidence of cross-contamination at plants where the contaminated ingredients were in use.

The ASPCA continues to warn pet parents to stay extremely alert to the situation. “Please stay abreast of recall news, which you can do via our Pet Food Recall Resource Center on our website, and remain extremely vigilant to your pets’ wellbeing. If they have eaten any of the recalled foods or show any of the signs generally attributed to kidney failure—or illness in general—please take them to your veterinarian immediately,” urged Dr. Murray.

The ASPCA continues to monitor the situation, and is providing regular updates and advice for pet parents at its Pet Food Recall Resource Center at www.aspca.org/recall.






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WePurrsevere Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 04:40 PM
Response to Reply #10
32. Thank you for providing the links. There's some exc. info especially on that Pet Food List site.
:yourock:

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tanyev Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 06:52 AM
Response to Original message
11. Seems like it was several weeks ago I was reading an article speculating
that it was the combination of melamine and cyanuric acid. Somebody just now decided to do an experiment and test it?

:grr:
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Name removed Donating Member (0 posts) Send PM | Profile | Ignore Fri May-04-07 08:03 AM
Response to Original message
16. Deleted sub-thread
Sub-thread removed by moderator. Click here to review the message board rules.
 
Gman Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 08:27 AM
Response to Original message
18. Cyanuric acid is used in swimming pools
Edited on Fri May-04-07 08:28 AM by Gman
it helps hold in chlorine. Cyanuric acid is a swimming pool chemical also known as a "stabilizer".
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LeftHander Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 08:39 AM
Response to Original message
19. MSM reported 18 animals have died.....wft...nt
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Buzz Clik Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 08:43 AM
Response to Reply #19
21. It ranges from 16 to over 8,000 depending on what you're reading.
The "official" numbers (17) are as worthless as the self-reported values (4000 to 8000). We'll never really know for sure.
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whopis01 Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 10:16 AM
Response to Reply #19
28. Who exactly are you referring to as the MSM?
Is it CNN? No, it couldn't be because they are reporting deaths in the thousands with over 17,000 complaints.

The FDA said Friday it had received more than 17,000 consumer complaints about the tainted pet food, including the deaths of 1,950 cats and 2,200 dogs.


Is it the New York Times? No, because they report the same numbers:
http://www.nytimes.com/aponline/world/AP-China-Pet-Food-Recall.html

Is it ABC? No...
http://abcnews.go.com/International/wireStory?id=3138880

In fact, most of the media is reporting the same story from the AP that reports deaths in the thousands.

Now there were earlier reports that had put the number of confirmed pet deaths at 16 or so, but there have been plenty of reports in the so called "MSM" referencing thousands of deaths for quite some time now.

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Buzz Clik Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 08:41 AM
Response to Original message
20. The research at Cornell was hinting at this result.
Edited on Fri May-04-07 08:41 AM by Buzz Clik
It's good that Guelph seems to have found the cause of this problem. The next step, of course, is to determine the concentrations of melamine and cyanuric acid in the food itself that will lead to problems. It seems likely that the most recalls probably were unnecessary, but we shall see.

From Wikipedia:

. Richard Goldstein of the Cornell University College of Veterinary Medicine hypothesized that the crystallization of melamine and cyanuric acid might cause cyanuric acid to remain in the kidneys for longer periods of time than when cyanuric acid in pool water is accidentally swallowed by people, explaining its apparent increased toxicity in this case. While it remains possible that cyanuric acid was added as a separate contaminant, Goldstein said that it was likely that it was the result of bacterial metabolism of melamine.<2> Cyanuric acid is a known intermediate byproduct of bacterial metabolism of melamine.<3>

<2> Swaminathan, Nikhil. "Were Our Pets Deliberately Poisoned?", Scientific American, April 25, 2007. Retrieved on 2007-04-26.
<3> Gang Cheng, Nir Shapir, Michael J. Sadowsky and Lawrence P. Wackett, Allophanate Hydrolase, Not Urease, Functions in Bacterial Cyanuric Acid Metabolism, Appl Environ Microbiol. 2005 August; 71(8): 4437–4445. doi: 10.1128/AEM.71.8.4437-4445.2005.


http://en.wikipedia.org/wiki/Cyanuric_acid

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DemReadingDU Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 09:42 AM
Response to Reply #20
25. The cyanuric acid is a byproduct of melamine?
Cyanuric acid is a known intermediate byproduct of bacterial metabolism of melamine.<3>


So it wasn't added to the wheat gluten like melamine.

But if melamine wasn't added to pet food, then this problem wouldn't have occurred?

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Buzz Clik Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 09:45 AM
Response to Reply #25
26. "if melamine wasn't added to pet food, then this problem wouldn't have occurred?" Yep.
It seems that the problems began with that questionable decision. I'm guessing that we will have a lot more answers very shortly about maximum permissable (trace) concentrations of melamine that will avoid these problems. This information will then dictate the extent of further recalls.
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I_Will Donating Member (211 posts) Send PM | Profile | Ignore Fri May-04-07 08:47 AM
Response to Original message
22. I can't help be but be a bit bummed...from a different angle...
I *love* all things Canadian, and I'm happy that this discovery was made by a caring and dedicated scientist.

But as a US citizen, it's kind of a bummer that apparently none of "our" scientistific institutions in the US (FDA and CDC included) spent "less than a second", working with already-identified compounds, to put one and one together on behalf of thousands of people and their pets here.

Just sayin'

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Buzz Clik Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 08:57 AM
Response to Reply #22
24. Read the post immediately above yours (#22). nt
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I_Will Donating Member (211 posts) Send PM | Profile | Ignore Fri May-04-07 10:15 AM
Response to Reply #24
27. Thanks!
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Buzz Clik Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 10:25 AM
Response to Reply #27
29. Your frustration was well founded.
Considering the incredible amount of "news" floating around about the scare aspect of this disaster, the acknowledge/science has been missing. Digging out even a shred of real information has been nearly impossible.
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daleo Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 06:34 PM
Response to Reply #22
34. John Kenneth Galbraith went to this university
When it was the Ontario College of Agriculture.

http://www.uoguelph.ca/atguelph/06-05-03/newsgalbraith.shtml
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DemReadingDU Donating Member (1000+ posts) Send PM | Profile | Ignore Fri May-04-07 05:10 PM
Response to Original message
33. evening kick
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