Scientists Discover Gene That Suppresses Tumours In A Number Of Cancers

[Swede]

Source: Medicalnewstoday.

A new Canadian study has discovered a gene that stops cancer tumours in a range of cancers, including breast, lung and liver. The researchers hope the discovery will help to improve treatments for many cancer patients.

The study is published in the early online issue of Nature Medicine.

Dr. Poul Sorensen a senior scientist at the British Columbia Cancer Research Centre and Professor at the Department of Pathology & Laboratory Medicine, University of British Columbia, led the research team of scientists from Canada, the US and Austria.


Read more: http://www.medicalnewstoday.com/articles/79759.php

[Imalittleteapot]

1. Thanks for posting.

Many people are waiting for cancer cures. Looks like Sorensen is on to something really big.

[Swede]

2. I hope so,too.

It touches every family.

[EVDebs]

3. Jeepers, a Canadian study. Those darn socialist medicine purveyors ! eom

[bamacrat]

4. The FDA would never approve gene therapy under a retarded administration.

Or B*sh would block it saying you were born with the genes you were born with.

[OzarkDem]

5. Hace 1 - a tumor suppressor gene

Similar to P53 gene, when active, it stops cancer cells from multiplying. While a potentially good target for treatment, it seems easier to block or turn off bad cellular activity than to switch on good activity.

from the article linked in the OP....

"The scientists also found that tumour growth triggered either by environmental factors (for instance being exposed to ultraviolet radiation and carcinogens) or by inheriting only one strongly suppressive version of another tumour suppressor gene, p53 (as opposed to inheriting strong variants or alleles from both parents) was faster in mice with low background levels of HACE1 expression.

HACE1 is in the class of genes known as E3 ubiquitin ligase, located on a region of chromosome 6q21 that is often involved in a range of human cancers.

The researchers said that HACE1 is probably helping to stop the tumours from growing by two mechanisms that arise in E3 ligase activity. One is by preventing adhesion-dependent growth, and the other is by stopping the activity of an oncogene, Cyclin D1. Cyclin D1 has been found to be over-expressed in more than 50 per cent of breast cancers for example. It plays an important role in controlling cell cycles."

[sybylla]

6. That is good news

One step closer all the time.