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Vanderbilt study helps lead to recall of medicine (Vioxx)

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NashVegas Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-01-04 08:01 AM
Original message
Vanderbilt study helps lead to recall of medicine (Vioxx)
Lookout for the lawsuits, when you see when this was undertaken.

A Vanderbilt University study published in 2002 on the potential dangers of high doses of Vioxx helped lead to drugmaker Merck & Co.'s decision yesterday to take the popular arthritis drug off the market.

Vanderbilt's study of 40,000 TennCare patients who used anti-inflammatory drugs in 2001 confirmed an earlier study commissioned by Merck that people who took 50 milligrams of Vioxx daily had double the risk of heart attack or stroke. A new study Merck commissioned found the same risk in people who take 25-milligram dosages.


http://tennessean.com/local/archives/04/09/58786120.shtml?Element_ID=58786120



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BlueEyedSon Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-01-04 08:02 AM
Response to Original message
1. Great, I have been taking it for a week!
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jmcgowanjm Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-01-04 08:45 AM
Response to Original message
2. Cox2 Inhibitors
I've been researching this stuff since before it came out.

Reason: Bleeding ulcers from stress and
taking an aspirin/day (dumb-causes internal
bleeding)

Looking for an aspirin sub I found what used to
be called superaspirin (worked same as
aspirin but no bleeding)

And more important, no acid reflux/pain
from stomach. Combined w/ Prilosec.

To make longstory short, Celebrex started competing
w/ Vioxx. I wanted to know which was better.

Vandy study came out. I stayed w/ Celebrex.

Cleveland Clinic Study came out and then I wondered
how long Merck would keep Vioxx on the street.

Now we know.
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HysteryDiagnosis Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-01-04 10:14 AM
Response to Reply #2
3. Look, it's as simple as this..... cyclo-oxygenase-2 inhibitors are not
the sole property of the drugcos.... they are not, they are not, they are not.... CoxII inhibitors EXIST IN NATURE.... they do EXACTLY the same thing that Celebrex and Vioxx do... not close to... not a little like them, but EXACTLY what they do... without increasing the chances of internal bleeding and or liver problems.

They exist, they are real, they are affordable... they are being used right now by hundreds of thousands of people around the world... problem is, they are needed by MILLIONS of people, and the only thing separating them from these products is INFORMATION.

A short list from the top of my head.... ginger, omega three oils, curcumin, tumeric, pycnogenol, vitamin C, Rosemary, Milk Thistle, Cat's Claw, etc....

There are many reputable companies out there producing formulas with several if not all of the preceding herbs/nutrients.

Read what is at these links and be free. This was written in 2000, so it just goes to show how ahead of the game Jack was and is.

http://www.stopinflammation.com/non-drug_remedies.html
>>The motivation was profiting from a potentially huge market. An estimated 40 million Americans suffer from some form of arthritis. In a typical year, physicians write about 60 million prescriptions for NSAIDS - to say nothing of their over-the-counter sales. However, each year some half-million people develop complications from NSAIDS, with an estimated 80,000 people requiring hospitalization and 8,000 dying.

Though touted for their relative safety, Cox-2 inhibitors may be far more hazardous than originally believed. While gastrointestinal problems with Cox-2 inhibitors occur less frequently, they can be severe. Just four months after the FDA approved Celebrex, 10 deaths from the drug were reported. One study has even suggested that Cox-2 is important to the gut and healing ulcers, suggesting that pharmaceutical tampering with the enzyme may not be wise.<<

http://www.stopinflammation.com/articles.html

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jmcgowanjm Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-02-04 08:37 AM
Response to Reply #3
4. Thanx Medialize, & yes I was taking Aleve before Celebrex
And like you said, the Aleve was only marginally better
for me.

And I'm going to be increasing my intake of
ginger.

Thanx again.

At least 20 million US suffer from IBS.
Women seem to get it in the stomach/colon.
And for some reason, men get acid reflux
and spastic esophagous.

I wonder why.
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goforit Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-02-04 08:42 AM
Response to Original message
5. Whoooo Hooooo.........Go VANDY!!!!!
That stuff is bad news!!!
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