http://www.nytimes.com/2005/06/17/nyregion/17ovary.html?Dr. Zoltan Ovary, an immunologist at New York University who conducted groundbreaking experiments that helped establish the mechanism that sets off allergic reactions, died on Sunday at N.Y.U. Medical Center in Manhattan. He was 98.
The cause was pneumonia, said a close friend and colleague, Dr. Susan B. Zolla-Pazner, a professor of pathology at N.Y.U.
In the early 1950's, while working at the Pasteur Institute in Paris and at the University of Rome, Dr. Ovary (pronounced oh-VAH-ree) and other scientists began a series of experiments that resulted in a strong allergic reaction in the skin of guinea pigs.
After introducing a blue dye into the animals' bloodstream, the researchers also injected antibodies into their skin, and subsequently set off a reaction with an antigen, a foreign substance that provokes an immune response. Blue spots appeared on the guinea pigs' skin, a sign that the antibody-antigen reaction had released a histamine and had dilated the blood vessels.
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