ScienceDaily (Feb. 15, 2008) — A research team at the Moores Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells.
Researchers led by Thomas J. Kipps, M.D., Ph.D., inserted a gene with the potential to activate an immune response -- a gene therapy protocol developed at UCSD -- into six patients with CLL, the most common form of adult leukemia. Several of the patients started making antibodies that reacted against their own leukemia cells. When tested in the lab, the antibodies also reacted with the leukemia cells of other patients with the disease.
The patient's own leukemia cells were modified outside of their body and given back as a vaccine," said Kipps. "The result raises hope that it may be possible to activate a patient's immune system against their own cancer."
http://www.sciencedaily.com/releases/2008/02/080211172550.htmCancer immunology is one of the most exciting fields in oncological research, IMHO.