Few drugs are more ubiquitous than acetaminophen, the pain reliever found in numerous over-the-counter cold remedies and the headache drug Tylenol. But last week, a federal advisory committee raised concerns about liver damage that can occur with overuse of acetaminophen, and the panel even recommended that the Food and Drug Administration ban two popular prescription drugs, Vicodin and Percocet, because they contain it.
The news left many consumers confused and alarmed. Could regular use of acetaminophen for pain relief put them at risk for long-term liver damage?
To help resolve the confusion, here are some questions and answers about acetaminophen.
What prompted the committee to look at acetaminophen in the first place?
Every year about 400 people die and 42,000 are hospitalized as a result of acetaminophen poisoning. When used as directed, the drug is not hazardous. But acetaminophen is now in so many products that it is relatively easy to take more than the recommended daily limit, now four grams.
“People often don’t know what products acetaminophen is in,” said Dr. Lewis S. Nelson, a medical toxicologist from New York University who was the panel’s acting chairman. “It isn’t that hard to go above the four-gram dose. If you took a couple acetaminophen for a headache until you got to the maximum dose, and then maybe later you take Tylenol PM and some Nyquil for a cold. And your back hurts, so you take Vicodin — by now you’ve probably gotten to a seven-gram dose.”
http://www.nytimes.com/2009/07/07/health/07well.html?th&emc=th