Single-dose swine flu vaccine in the works

[OhioChick]

Source: Times of India

4 September 2009, 01:20am IST

NEW DELHI: A single-dose H1N1 swine flu vaccine may soon happen. Contrary to what was earlier expected, the vaccine against H1N1 may not be multi-dose, as results from a pilot study of Novartis H1N1 candidate vaccine revealed a strong immune response after just one shot. The vaccine might be used in trials in India as well.

Scientists from the University of Leicester, who tested the vaccine on 100 healthy volunteers aged between 18 and 50, found that more than 80% of the volunteers showed a strong, potentially protective immune response after one dose, with more than 90% showing the same response after two doses.

Trial leader Dr Iain Stephenson said, "The clinical trial of Novartis MF59-adjuvanted cell-based H1N1 vaccine indicates that the swine flu vaccine elicits a strong immune response and is well-tolerated. The results showed that the serum antibody responses were highest among subjects who received two doses of vaccine. However, a single vaccine may be sufficient to protect against H1N1."

The trails have a significance for India as it is one of the vaccines being eyed by India to be given to healthcare and emergency workers around February next year.


Read more: http://timesofindia.indiatimes.com/news/india/Single-dose-swine-flu-vaccine-in-the-works/articleshow/4969323.cms

[CountAllVotes]

1. uh huh

one dose does it or is it two? And where is this B.S. vaccine being made? India, China or the USA?

They can shove this "vaccine" where the sun don't shine no more!

:kick:

[Name removed]

2. Deleted message

Message removed by moderator. Click here to review the message board rules.

[Why Syzygy]

5. You are welcome

to skip the forum if it is troubling for you. We all have DU memberships with the same benefits you do. We are allowed to state our opinions in a civil manner. You are bordering on non-civility. Perhaps you would be happier in a different forum. I know that personally I have to avoid certain places at DU for my own mental stability.

[Odin2005]

3. Wow, an anti-vaxer pops up in thw first post.

:eyes:

[Why Syzygy]

4. MF59 - squalene

Has been highly controversial. The alt-medical sites hate it.

For example (no excerpt posted):
http://blogs.mercola.com/sites/vitalvotes/archive/2009/07/17/Squalene-The-Swine-Flu-Vaccines-Dirty-Little-Secret-Exposed.aspx

Other scientific examination of the subject:

III. Animal models
Here I will not repeat what I have already written about before in part I of this diary, but will add some very recent references to show both the reactogenicity of squalene and similar adjuvants, and their continued use, indeed efficacy, in inducing autoimmune conditions for experimental purposes.
2000 Carlson The Endogenous Adjuvant Squalene Can Induce a Chronic T-Cell-Mediated Arthritis in Rats
2001 Holmdahl Arthritis induced in rats with nonimmunogenic adjuvants as models for rheumatoid arthritis.
2002 Holm The arthritogenic adjuvant squalene does not accumulate in joints, but gives rise to pathogenic cells in both draining and non-draining lymph nodes
2003 Satoh Induction of lupus autoantibodies by adjuvants
2004 Adjuvant oil induces waves of arthritogenic lymph node cells prior to arthritis onset
2004 Kuroda Autoimmunity induced by adjuvant hydrocarbon oil components of vaccine
2006 Kuroda Induction of lupus-related specific autoantibodies by non-specific inflammation caused by an intraperitoneal injection of n-hexadecane in BALB/c mice
http://www.newfluwiki2.com/showDiary.do?diaryId=1758


For that reason, I'm going to explore a couple of articles written by top experts and published in peer-reviewed journals on this subject. Since these experts are also employed by manufacturer of MF59, Chiron previously and now Novartis, I believe we will not be in danger of ignoring any data that is favorable to their case.
http://www.newfluwiki2.com/showDiary.do?diaryId=1772

[truedelphi]

6. THanks for info. Interesting information about the arthritis in rats.

Currently, the kids in this nation have unusual numbers of arthritis cases. I don't remember anyone under the age of twenty having arthritis when I was gorowing up. But kids now have arthritis, along with MS!

And in addition to the squalene, the vaccines are made in very few labs, with most of our labs probably not passing inspection if held to standards required in European nations. But labs here are fully warned about the inspections before hand (in many cases.) And found to be sub par when they aren't.

[WillYourVoteBCounted]

7. I'm waiting for Pfizer to come out with expensive vac, to recoup

from their recent losses.

But I won't be participating in the swine flu vaccine program