Having just re-read the thread, I can find no post claiming that either condition is a fiction. Instead, skeptics are quite reasonably taking issue with the post mortem diagnosis of (coincidentally enough!) monumental figures from history in order to assign these conditions to them for some reason.
These are spectrum phenomena only recently understood
at all, and it's hard enough to diagnose someone who's sitting in the chair opposite, let alone someone who's been dead in a box in Vienna for 2+ centuries.
Nothing, and I mean
NOTHING positive is gained through the propaganda technique of Fristian retrodiagnosis.
And as absurd as that practice is, it's even more offensive IMO to presume to diagnose living people without their consent or participation. If they have revealed their conditions on their own, then that's another matter (people such as Dan Aykroyd, for example). But to declare someone an "aspie" just because some of that person's behaviors seem to match the nebulous diagnostic criteria?
Sorry, but that's just bullshit.
And this part:
They seem to be the driving creative forces and great minds of the human race.
is simply nonsensical. Since there is no good evidence that these "great minds of the human race" actually had the conditions that you ascribe to them, then it is the height of folly to lionize them as you propose.
However, I share your view that we shouldn't medicate people with Autism or Asperger's unless doing so will prevent them from harming themselves or others, or unless their quality of life will be so greatly improved that they themselves (or someone legally empowered to consent on their behalf) agree to the treatment.