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Most - if not all - of the Senate's 55 Republicans are expected to line up behind Alito.
Judiciary chairman Arlen Specter, R-Pa., predicted that all eight of the committee Democrats would vote against Alito, whenever the vote is held. But on the final Senate vote, "I think there will be a little deviation," he said.
The 44 Senate Democrats have been mostly silent about their intentions, although committee senators like Edward Kennedy of Massachusetts and Charles Schumer of New York have indicated they will oppose Alito's confirmation.
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But five of the seven Republican members of the "Gang of 14" - centrist senators who defused a Senate showdown over judicial filibusters last year by saying "extraordinary circumstances" would be needed - already have said they will not help Democrats if they attempt to filibuster Alito's confirmation.
Sens. Lindsey Graham, R-S.C., and Mike DeWine, R-Ohio, both Judiciary Committee members, made that commitment before the confirmation began, and Sen. Olympia Snowe, R-Maine, agreed Thursday that a filibuster would not be justified.
On Friday, two other GOP "Gang" members jumped in. Sen. Susan Collins "does not see a justification for and would not support a filibuster," spokeswoman Jen Burita said. Sen. Lincoln Chafee, R-R.I., "has said he has not seen any extraordinary circumstances," spokesman Stephen Hourahan said.
The last two - GOP Sens. John McCain of Arizona and John Warner of Virginia - have not commented, but one of the Democratic members of the "Gang" has.
"So far I have seen nothing during my interview with the nominee, the background materials that have been produced or through the committee process that I would consider a disqualifying issue against Judge Alito," said Sen. Ben Nelson, D-Neb.