Even though I left there in 1998, I had a complete physical exam earlier this year conducted by a DOE contractor doing a study on the health profiles of (former) Hanford employees. I've heard nothing back from either the physical or the study. I don't know if I will.
There have been several 'studies' of radioactive waste leaking into the ground water (and then into the Columbia River) but the "statistical assumptions" have, at least in one of the studies I knew about when I was there, been highly skewed in order to generate more 'acceptable' results. Clearly, any such study is heavily reliant on sampling and testing and the assumptions underlying such a study are extensive - including the flow of groundwater, soil percolation, sources of contamination, etc. Nonetheless, it can be reliably said that radioactive toxic waste IS reaching the Columbia River. Some biological anomalies have been noted but, needless to say, their attribution and extent is highly politicized.
It's a HUGE political issue and watchdog groups go bald pulling their hair out and beating their heads against the political wall. The whole site is a huge rice bowl for over a dozen private contractors. Over 90% of the people who work there are (technically) employees of the contractor. When the DOE sneezes, the whole Tri-Cities (Richland, Kennewick, and Pasco) area gets pneumonia. Billion$ in contracts.
To get an overview (satellite), you can look at the Google Map here ...
http://maps.google.com/maps?t=h&om=1&ie=UTF8&ll=46.55408,-119.534168&spn=0.631778,0.866547&z=10Virtually everything to the north and east of Hwy 240 and to the south and west of the Columbia River (loop) is the Hanford Nuclear Reservation. To the southeast, you'll see Richland and West Richland (where I lived). It's a HUGE area. Don't be distracted by the apparent town names (when you zoom in) scattered in that area - they were evacuated over 60 years ago. NOBODY lives on the reservation. The built-up area just to the northeast of Hwy 240 is the 200 West area.