SO Big Pharma wins today's round at the FDA: AVANDIA stays on the market.

[Nikki Stone1]

How many more diabetics will have to get heart attacks before they remove the drug from the market? And since when is the New England Journal of Medicine "not enough research"? (Predicatably, that was what Glaxo-Smith-Klein had to say.)

[HysteryDiagnosis]

1. Protect yourself

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17116186&ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Oxidative burden in prediabetic and diabetic individuals: evidence from plasma coenzyme Q(10).
Lim SC, Tan HH, Goh SK, Subramaniam T, Sum CF, Tan IK, Lee BL, Ong CN.

Department of Medicine, Alexandra Hospital, Singapore 159964, Republic of Singapore. [e-mail]

AIM: Individuals with diabetes and prediabetes are at risk of vascular injury. However, the exact mechanisms are unclear. The mitochondria mobile electron carrier coenzyme Q(10) (CoQ(10)) is a potent lipophilic antioxidant. We hypothesize that oxidative stress, detectable as changes in plasma CoQ(10) concentrations and composition, plays an important role in vascular disease in diabetes.

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=15363656&ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
1: Life Sci. 2004 Oct 8;75(21):2505-13.Click here to read Links
Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type II.
Liu X, Wei J, Tan F, Zhou S, Würthwein G, Rohdewald P.

Guang An Men Hospital of Chinese Medical Science Research Institute, Beijing, PR China.

A double-blind, placebo-controlled, randomized, multi-center study was performed with 77 diabetes type II patients to investigate anti-diabetic effects of the French maritime pine bark extract, Pynogenol.

[Bitwit1234]

2. Since they know it is toxic, diabetics should refuse it. I know I am

I take glipizide. Which works well and I wouldn't take any other. I go on line an research the medicine after the doctor prescribes it, if I am not sure I ask the doctor why she prescribed it.

[Horse with no Name]

3. The serious thing about this is

The second it goes off the market, the lawsuits start. The FDA is simply protecting one of their corporate masters.

[Nikki Stone1]

4. Exactly.

Meanwhile, some doctors will continue to prescribe it.

[Horse with no Name]

5. Doubtful they will prescribe it to anyone else

They are just going to quietly take their patients off of it and hope the stench goes away on it's own.

[Oldenuff]

6. What did you expect?

Glaxo is simply getting their value from the campaign contributions.Did we really expect anything less?