Speaking from personal experience
I watched my very wonderful sister die of this horrible disease 2 years ago. I know what stages of Melanoma my sister was in when various things were happening. At the stage that the tumors left the first site of occurrence and traveled to distant spots or the
opposite side of the body this was evidence that the cancer had entered the lymphatic system and was now freely traveling throughout the body via the lymphatic system. (see:
http://www.melanomacenter.org/staging/stage3.html ) Since Sen. McCain has had the lymph nodes in the left side of his face removed (the "chipmunk cheeks" are due to lymph edema) a tumor then showed up on the RIGHT side of his face pointing to his being in a more advanced stage of the disease than he admits. John McCain had the lymph nodes removed as a "precautionary measure"(The operation was performed mainly to determine whether the melanoma.... had spread from his left temple to a key lymph node in his neck; a preliminary pathology test at the time showed that it had not.")
http://www.nytimes.com/2008/03/09/us/politics/09mccain.html?pagewanted=1The operation also involved the removal of the parotid salivary gland and
33 lymph nodes in the senator's neck. No evidence of cancer was found in the lymph nodes, according to the Mayo physicians. This may have been quite a radical approach. I will leave it to any oncology doctors on this board to comment on that.
However, not all Melanomas are the same. My sister had first occurrence on her toe. Since this is a small area close to the bone it had probably already entered her bone by the time she even had it checked and very quickly amputated. Still, at the point that she was in Stage III she had less than 2 years left to live. The doctors at Duke Medical Center used the standard Breslow measurement to determine staging (
http://www.cancer.org/docroot/CRI/content/CRI_2_4_3X_How_is_melanoma_staged_50.asp )
But as for Senator McCain, his year 2000 tumor was the most significant of his four melanomas. It was 2 centimeters in size and 2.2 millimeters thick. Its removal left a wound that was 6 centimeters by 6 centimeters.
http://www.npr.org/templates/story/story.php?storyId=90781894Sen. McCain's Melanoma in my estimation (and I am no doctor) is probably in Stage III by now. This gives him a very grim prognosis for getting through even the first 2 years of a presidency, never mind 4. If you want to read more:
http://www.bcm.edu/oto/grand/3493.html And if you really want to do something wonderful, then please donate something to the Melanoma Research Foundation so more great people like my sister don't need to suffer and die from this horrible disease.
http://www.melanoma.org /