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Melamine Scrap Contains Chemical Linked to Blindness: Why No Action From the Bush FDA?

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McCamy Taylor Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 07:40 PM
Original message
Melamine Scrap Contains Chemical Linked to Blindness: Why No Action From the Bush FDA?
Edited on Sun Nov-16-08 08:01 PM by McCamy Taylor
I. Forget Health. The FDA’s Job is to Decide How Much Melamine the Market Will Allow

It is hard not to think the worst of the Bush administration. They took an outbreak of food poisoning this summer and botched it so badly that they just about killed the Mexican tomato industry---while doing a big favor for the greenhouse tomato industry, which should have seen prices fall as summer crops came in. It took local public health officials to locate the true source---peppers. Score another one for rising food prices.

Dixiegrrrrl has an excellent piece in DU today about how the FDA has sanctioned trace amounts of the plastic melamine in our foods

http://www.democraticunderground.com/discuss/duboard.php?az=show_mesg&forum=389&topic_id=4471483&mesg_id=4471483

For those who like chemistry, wiki has a nice write up about melamine here:

http://en.wikipedia.org/wiki/Melamine

Basically, this chemical has lots of potential uses in fire retardants, plastics, pesticides. However, during the last few years, China has faced a severe surplus of the material and seen world prices for it drop. That is why there was so much of it lying around. Melamine itself is not particularly toxic. But note also that one of the breakdown products is cyanuric acid, and that the parent melamine can then combine with its own breakdown product cyanuric acid (I guess you could call this incest) to produce the chemical melamine cyanurate which forms crystals in water----and it is this crystalline compound that causes the kidney stones and kidney damage that make melamine toxic to pets and humans.

Since melamine has become dirt cheap and abundant and since it is loaded with nitrogen---which is also found in protein----Chinese food manufacturers decided to throw it in a variety of food products to make milk, gluten, eggs and other protein rich foods look extra protein rich when they are tested for their nitrogen content. If the melamine had ever been pure melamine, maybe no one would have known the difference. However, it was not pure, and it reacted with impurities. The new, toxic form of the substance killed pets and later caused an epidemic of kidney stones and renal failure in Chinese infants fed contaminated formula. Note that a long term effect of the drug can be bladder cancer so those poor children are not home free.

One rationale for allowing trace amounts of melamine in foods is the fact that plastics can contain melamine. Food is packaged in plastic, and therefore, theoretically, tiny amounts of melamine can leech into foodstuffs from the packaging even if the food is unadulterated. However, as Dixiegrrrrl has written, the FDA’s action seems to sanction melamine contamination and other deceptive, cost saving measures practiced by China. This aids China. It also helps the U.S. food industry. As long as food manufacturers in the U.S. know that they can get away with selling products with small amounts of poisonous contaminants, they will apply no pressure on China to clean up its act. If U.S. buyers continue to demand ridiculously low priced food stuffs out of China, with no concern about how many corners are cut to achieve the cost savings, China will continue to use its ingenuity to cuts those corners. In a few years, the FDA may have a list of a dozen or more poisons that China is allowed to add to our food supply, each in a small amount, the sum of which could well kill us---slowly of course, since neither Chinese nor American businessmen want to lose their market.

There is also a kind of sad fatalism at work here. When did the official attitude towards melamine change from let’s clean it up! to can’t we all get along? About the same time that countries like New Zealand realized that melamine is everywhere. From this September.

http://www.odt.co.nz/news/national/24232/low-level-melamine-acceptable-food-safety-experts

New Zealand food safety experts say they are "struggling" to determine a safe level of melamine in the nation's diet, but have opted for a threshold of 5 parts per million.

The New Zealand Food Safety Authority (NZFSA) today said that melamine now appeared to be widespread in the food chain, but claimed it was harmless at low levels.

"We know that the presence of this chemical is part and parcel of our life today, apparently leaching from plastics and contact materials during processing and packaging in trace quantities," said NZFSA director of compliance and investigation Dr Geoff Allen.

"At low levels it causes us no harm," he said.


We wish. We hope. We pray.

Everyday, we are told that we just have to suck it up and live with high ozone in our city air----because that is the cost of prosperity and a healthy tax base. Even if the high ozone is killing unborn children with prematurity (paging Right to Life!) children with pneumonia and adults with heart attacks and everyone with asthma. We are told that cancer causing chemicals are also a price for economic prosperity---though it’s a funny thing, the carcinogenic chemicals always wind up next door to the poorest, most oppressed, usually minority communities that share in the wealth least. Now, the FDA is trying to convince people that food adulteration is essential for our economic survival. And anyway, there is nothing that we can do about it.

Eat your plastic. It’s good for the economy.

II. What You Do Not Look For Can Not Hurt You(r Reputation): Ammeline and Blindness

Kidney stones are scary. Blindness is scarier.

I keep waiting for some health agency or regulatory body to issue a statement about ammeline . So far, I have not even seen a reference to the episode which occurred in Japan way back in the 1970s, when chicken feed was contaminated with the breakdown product of melamine in order to artificially increase its nitrogen content (sound familiar) and a whole bunch of baby chicks went blind. That’s because ammeline does not attack the kidneys like its parent compound. It goes after the eyes.

Here is some information about ammeline:

http://books.google.com/books?id=V7D020dl3_oC&pg=PA78&lpg=PA78&dq=melamine+retina&source=web&ots=S1E9Fz73y-&sig=893dq73Cm49wVFqheH-ya-KMaC4&hl=en&sa=X&oi=book_result&resnum=10&ct=result#PPA78,M1

Note that it causes retinal edema, degeneration and finally detachment over the course of a week when it is eaten in large enough quantities.

Here is wiki on ammeline. It is another hydrolysis product of melamine. Replace one ammonia with one hydroxyl ion and there you go.

Before you say But the Chinese would only adulterate their food with the finest grade melamine check out these two articles about how producers of milk and other protein food used melamine scrap in their food. Because it was cheap.

http://www.nytimes.com/2007/04/30/business/worldbusiness/30food.html?_r=1&oref=slogin

For years, producers of animal feed all over China have secretly supplemented their feed with the substance, called melamine, a cheap additive that looks like protein in tests, even though it does not provide any nutritional benefits, according to melamine scrap traders and agricultural workers here.

“Many companies buy melamine scrap to make animal feed, such as fish feed,” said Ji Denghui, general manager of the Fujian Sanming Dinghui Chemical Company, which sells melamine. “I don’t know if there’s a regulation on it. Probably not. No law or regulation says ‘don’t do it,’ so everyone’s doing it. The laws in China are like that, aren’t they? If there’s no accident, there won’t be any regulation.”




Melamine scrap contains a lot more than just melamine.

http://en.epochtimes.com/n2/china/melamine-china-milk-powder-5370.html

If the melamine contained in the milk powder or liquid milk comes from adding melamine scrap, there will be more ingredients to be worried about.

A reporter in Caijing learned that as an impure form of the chemical, such leftover melamine scrap often contains urea, ammonia, silica, potassium nitrate, sodium nitrite, acetic acid, and activated carbon. Sodium nitrite is also internationally recognized as a carcinogen.
According to China’s State Administration of Quality Supervision, Inspection and Quarantine (SAQSIQ), the content of melamine in Sanlu baby milk powder products is as high as 2,563 milligrams per kilogram. Some industry insiders said that the high concentration of melamine in some brands of milk powder could be linked to hidden operating rules for milk powder manufacturers.


http://itchmoforums.com/recall-nonpet-food/melamine-suspected-chinese-officials-say-baby-formula-tied-to-kidney-stones-t6256.1245.html

Scroll down the page here to see that ammeline was found in the wheat gluten that poisoned dogs last year in amounts up to 10mg/kg (and then check out the toxicology reference above to see that amounts of 0.5% chemical content by weight caused blindness in some baby chicks after only two days). I have found studies of animals whose kidneys were tested for effects from contaminated Chinese protein but none who have had retinal exams. If anyone knows of any studies, please link them! There is no way to know what the effect of ammeline is on the eyes of infants (like the thousand infants sickened by China’s contaminated formula) or young pets if doctors and veterinarians do not look for retinal damage . However any animal with a developing eye may have the same problem which the baby chick’s did in Japan. There is also no way to know if healthy or diabetic adults may have suffered eye problems from consuming food contaminated with melamine scrap---unless someone examines their eyes. The FDA and the NIH should be studying this problem. Instead, they are strangely silent.

III. Look Out for Formoguanamine, Too

Look, I am no chemical engineer. I have never worked in a chemical factory, and I do not know how they manufacture or store melamine scrap (under what temperature or conditions.) I am just going on hunches here, erring on the side of caution since China wants to cover it all up---and so, apparently, does our own FDA. Here is what wiki says (in a nice summary of the Chinese faux protein scandal)

http://en.wikipedia.org/wiki/Chinese_protein_export_contamination

Melamine production in China has also been reported as using coal as raw material.<6> This production has been described as also producing "melamine scrap" which is not "pure melamine but impure melamine scrap that is sold more cheaply as the waste product after melamine is produced by chemical and fertilizer factories here."<41> Shandong Mingshui Great Chemical Group, the company reported by the New York Times as producing melamine from coal, produces and sells both urea and melamine but does not list melamine resin as a product.<42> Melamine production in China has increased greatly in recent years and was described as in "serious surplus" in 2006 .<43> In the United States Geological Survey 2004 Minerals Survey Yearbook, in a report on worldwide nitrogen production, the author stated that "China continued to plan and construct new ammonia and urea plants using coal gasification technology."<44>
The off-gas in production contains large amounts of ammonia (see melamine synthesis). Therefore melamine production is often integrated into urea production which uses ammonia as feedstock. Crystallization and washing of melamine generates a considerable amount of waste water, which is a pollutant if discharged directly into the environment. The waste water may be concentrated into a solid (1.5-5% of the weight) for easier disposal. The solid may contain approximately 70% melamine, 23% oxytriazines (ammeline, ammelide and cyanuric acid), 0.7% polycondensates (melem, melam and melon).


They make melamine scrap from coal.

Think about what a coal miner's lung looks like.



Now just imagine what kind of chemicals must be in the scrap that they throw away. And imagine eating a big heaping plate full of it. Yum.


The point I am trying to make is who knows what is in scrap melamine. Maybe more than the FDA is checking for. I want to mention formoguanamine because it is formed from the same chemical used to make melamine

http://patents.ic.gc.ca/cipo/cpd/en/patent/508090/summary.html

And researchers in Japan have shown that two injections of the compound can induce retinal blindness in an adult bird.

http://www.springerlink.com/content/y1n1558732312747/

Yeah, I know PETA is peeved. But the take home message is that there may be any number of contaminants in melamine scrap that have unsuspected side effects. And some of those are not on the FDA list when they turn on the gas chromatograph or mass spectrometer. Some of these contaminants may have been deliberately left off the list.

If anyone knows why formoguanamine can not be formed by hydrogenation of dycyandiamide under the conditions in which they manufacture melamine scrap or later when the stuff is sitting around, please let me know. My concern for Chinese babies is that many thousands may have consumed lots of contaminants in their early months. Maybe they escaped kidney damage but other organs—like their eyes---were affected, and no one will know until they start having problems in school. And what about people in the United States who have been using lots of powdered protein supplements? That includes diabetics and some very sick people who need to keep their strength up. If the manufacturers of nutritional supplements have been buying their “milk powders” on the world market, what are the odds that some Chinese contaminants have gotten in there? What about exercise enthusiasts who use protein powders daily to help build up muscles while keeping their fat intake low? Could they be the victims of slow poisoning?

If melamine scrap had been added to our food supply by a rival food producer---say a member of the European Union like France---all products would have been yanked from the shelves and NIH studies would already be underway. Dixiegrrrrl is correct. China is being protected, because it is a partner in the crimes of the Bush administration and the criminal activities of too many American corporations.
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Rosa Luxemburg Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 07:47 PM
Response to Original message
1. The Bush admin. doesn't care and never did.
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KakistocracyHater Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 07:58 PM
Response to Original message
2. but the Material World is EVIL
the 12th House has ALWAYS tried to destroy the 1st House, so ALL pisces-based deities & their followers more or less do this-why the surprise? The 1st House has always been forced to fight to defend & protect life here. Good thing most people don't know what SOTEIR/SOTEIRA means..... :dunce:
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Mojorabbit Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 08:04 PM
Response to Original message
3. I just got an email alert
from promed a few minutes ago.
MELAMINE - USA: ALERT
*********************
A ProMED-mail post
<http://www.isid.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

******
<1>
Date: 14 Nov 2008
Source: BBC News
<http://news.bbc.co.uk/2/hi/americas/7728605.stm>


US 'import alert' on China food
-------------------------------
US authorities have issued a nationwide "import alert" for
Chinese-made food products in the wake of the melamine contamination
scandal. The US Food and Drug Administration (FDA) had already issued
an alert warning Americans not to consume Chinese products containing
milk. Thousands of Chinese have been poisoned this year.

The latest alert goes beyond dairy products to such items as drinks,
sweets, and baby and pet food. It also allows US inspectors to seize
any Chinese products suspected of being contaminated.

Safety issues
-------------
The earlier restrictions were put in place on diary products after 4
Chinese children died from kidney failure and thousands more people
fell ill after consuming dairy products laced with melamine, which is
normally used in making plastics and fertiliser.

The FDA has now added more than a dozen other goods imported from
China, including biscuits, instant coffee and tea products.

In addition, US officials will be travelling to China next week for
consultations with the Chinese about safety issues. The FDA is also
planning to open three new offices in China to check products
intended for the US market.
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dixiegrrrrl Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 09:15 PM
Response to Reply #3
7. The FDA now allows melamine in food, yet "inspectors" are trying to keep it out?
The agency that allows poisoned food to increase profit,
or the gov't that says we are "stopping bad China food at the border"?

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amdezurik Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 08:10 PM
Response to Original message
4. China owns them...
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lazyriver Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 08:39 PM
Response to Original message
5. Bookmarking for later but K&R for importance. nt
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Mnemosyne Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 09:08 PM
Response to Reply #5
6. Same here, lazyriver. KnR, with thanks to McCamy T, for excellent work! n/t
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knitter4democracy Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 09:15 PM
Response to Original message
8. Great. Renal failure of my remaining kidney is just what I need.
Bastards.
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dixiegrrrrl Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 09:18 PM
Response to Original message
9. Is there a way we can have this growing amount of DU research in one place?
I fear it is the tip of the ice berg, and that all the stuff we are pulling together may be irretrievable in the near future.
You have some great links to explore.
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HCE SuiGeneris Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 09:48 PM
Response to Original message
10. Error: You've already recommended that thread.
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bleever Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 09:50 PM
Response to Original message
11. The unasked question about all this melamine:
Edited on Sun Nov-16-08 09:53 PM by bleever

Is it in fact produced from waste animal urine?

There are many signs pointing to this possibility. The chemistry and the industrial paradigms of China both point to this as a strong possibility that needs to be investigated on an international level.

Think about melamine's key "benefit" as a nitrogen supplement. Nitrogen is a significant constituent in animal (and human) urine. Think about the vastness of America's problems with disposing of vast lagoons of hog urine. Think about the role of urea and cyanuric acid. (And if you find your suspicions raised further by "formoguanamine", you may be on the right track).

Think about kidney failure, and how it relates to the body's failure to eliminate waste through urine properly.


All of this isn't my own thinking; it comes from discussions I've had with the bioscientist and medical professional I live with. She was one of the first in the nation to identify the problems with the pet food disaster of the last couple years.


Bookmark this. Because if melamine products were known to originate in animal waste, they'd never be allowed on the international market. Billions of dollars are at play here, and the need to suppress this truth will be commensurate with the amount of revenue at risk.

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bluesmail Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Nov-16-08 09:51 PM
Response to Original message
12. If a big-ass corporation can make a profit off ANYTHING
They will and they will NOT be held liable, (at least with the current adm.) I am really looking forward to the new administration, barring nothing AWFUL happens between now and Jan 20th. It's almost too good to be true and I hope I didn't jinx it with what I wrote.
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liberal_rxstudent Donating Member (69 posts) Send PM | Profile | Ignore Sun Nov-16-08 11:19 PM
Response to Original message
13. ugh...
this is not at all shocking- considering some of the swine working there currently. It is my desire to one day be able to contribute to society by working at the FDA- and I will be the first to say that it is in serious need of restructuring. It breaks my heart to learn that the FDA is at it again...it is too familiar. After graduation, I would love to be there when the FDA once again places safety as its main objective. I am truly hopeful. Until then...there were most definitely be more of this kind of news. As for your querie about formoguanamincan (I'm not familiar with it), I'll try looking into that.
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CoffeeCat Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 01:55 PM
Response to Original message
14. Last month, I purchased a few bags of...
...chocolate coins, the ones wrapped in foil. They were on clearance at Walgreen's for
25 cents. I bought them to give out to the kids we know--for trick or treat.

Each little bag had about 6 coins in it. I ended up eating all of them!

Then, I find out that certain chocolate coins were tainted with melamine, but our government
swears that those chocolate coins were only disseminated in Canada.

Since mid October, I have had a severe cough and sore throat that will not go away. I
cough to the point of feeling like I can't breath--with my eyes watering and the sensation
that I'm choking. I'm very fatigued as well.

I have no wrappers left from the chocolate coins, but the picture of the tainted coins looks
identical to what I purchased.

I doubt I ingested melamine, but it's a real pain in the ass to have to wonder about the
confluence of all of these factors!
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McCamy Taylor Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 02:07 PM
Response to Reply #14
15. Safest bet is eat a wide variety of foods, that way you have less chance of getting poisoned
because you will not be exposed to any one thing too much. Also you have a better chance of getting all your trace elements and minerals that way. And of course, eat fresh veggies.fruits and antibiotic/chemical free whenever possible and cook it yourself.

Worst thing you can do is rely upon one brand of a specific food too much and then find out that it was adulterated after you have eaten a few tons of it.

One reason I am interested in this whole melamine business is my diabetic/high cholesterol husband used to drink protein powder supplements daily after exercising since they were low fat. During that time he got recurrent nasty kidney stones and developed an acute episode of retinal inflammation with permanent retinal damage (not the typical diabetic MAs) that the eye doctors could never explain. Has had no problems with kidney stones or his eyes since he stopped the powdered protein supplements. No MAs have formed since then and his kidneys have been fine. I am about 80% sure there was something in that protein powder besides milk whey. The makers of protein supplements would be a natural buyer of Chinese milk since they would need large amounts and the Chinese would have the lowest prices (and would offer high nitrogen content).
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CoffeeCat Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 02:10 PM
Response to Reply #15
16. That is very troubling...
Do you have any of the protein powder?

Could you have it tested?

We're probably all ingesting it.
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HiFructosePronSyrup Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 02:24 PM
Response to Original message
17. Fear-mongering baloney.
This is "fluoride saps our precious bodily fluids" nonsense.

Plastic dinnerware leeches some trace amount of melamine into food, which is why the FDA set a trace limit. The amount of melamine doped into products in China (many of these from American businesses, btw) far exceeded a trace amount. The issues has nothing to do with each other.

"If anyone knows why formoguanamine can not be formed by hydrogenation of dycyandiamide under the conditions in which they manufacture melamine scrap or later when the stuff is sitting around, please let me know."

Could you rephrase that please?


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McCamy Taylor Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 04:48 PM
Response to Reply #17
18. What if they set trace limits because American Cyanamid Co. has been selling melamine to pig
farmers for feed and it has been entering our food supply that way, and now ACC is scared shitless of being sued, and so the FDA is going to cover ACC's butt?

Not to say that I have proof that this company has been the source, but you never know. Someone needs to find out where they got the melamine they put into the livestock feed.

I guess I know what my next journal will be about.
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HiFructosePronSyrup Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 05:09 PM
Response to Reply #18
19. What if chemtrails are bigfoot poop?
McCamy, there have been traces of melamine in our food for the last eighty years or so.
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McCamy Taylor Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 05:20 PM
Response to Reply #19
20. But now animals and children have DIED and had renal failure. In vivo proof of toxic levels added
Edited on Mon Nov-17-08 05:21 PM by McCamy Taylor
to the food. That is different from trace contamination---and you know it.

And here is a possibility that needs to be evaluated by the medical community even if it spells doom and gloom for the manufacturers of plastics---what if the plastic products that we use in our houses or which store our food degrade to produce the toxic forms of melamine which cause kidney stones? How much renal disease is actually due to the use of plastics? This would be an easy and fascinating study for a researcher to undertake. Negative results would confirm that the FDA is ok allowing some melamine in our food. However, it the studies show a positive correlation between the use of melamine containing plastics and kidney stones, that would be a sign that we need to rethink our use of these items.

The plastics industry would hate this kind of research, but considering how much disability and cost kidney stones cause each year, it would make sense from a public health point of view to check it out, not just say (as the FDA has done) this is how it is so we have to live with it

Once upon a time, tobacco farmers made a living off addicted smokers and their response to suspicions that tobacco caused disease was "We need the business, so don't rock the boat."

The status quo should not be preserved, just because it has been that way "for the last 80 years".

Blacks were kept from voting for over 80 years after the end of the Civil War and that did not make that right, either.
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HiFructosePronSyrup Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 05:31 PM
Response to Reply #20
21. They've died due to massive doses.
Not in the trace doses found in food stored in plastic containers.

"That is different from trace contamination---and you know it."

Exactly my point. So what are you griping about?

"Blacks were kept from voting for over 80 years after the end of the Civil War and that did not make that right, either."

I'm sorry. Are you trying to be clever?

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McCamy Taylor Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 06:40 PM
Response to Reply #21
22. Maybe this WHO Document will help.
http://www.who.int/foodsafety/fs_management/Melamine.pdf

It talks about how a figure for recommended allowable maximum daily intake of melamine is calculated. Note also that it states that "no human data can be found for the oral toxicity of melamine." They are extrapolating from animal studies. Also note that there is no information about infants. Also the ratio of melamine to cyanuric acid, the compound with which melamine reacts to form water insoluble crystals could affect the toxicity of the melamine. I.e. one product with x% pure melamine might not have the same toxicity as another product that had y% melamine and z% cyanuric acid which might not have the same toxicity as a third with y1% melamine and z1% cyanuric acid. Therefore, measuring total melamine alone may not give you a true estimate of the toxicity of foods, especially if foods at any point along the food chain are still being adulterated with melamine scrap.

Note that cyanuric acid is added to animal feed in the US. The FDA allows this.

http://en.wikipedia.org/wiki/Cyanuric_acid

FDA permits a certain amount of cyanuric acid to be present in some non-protein nitrogen (NPN) additives used in animal feed and drinking water.<7> Cyanuric acid has been used as NPN. For example, Archer Daniels Midland manufactures an NPN supplement for cattle, which contains biuret, triuret, cyanuric acid and urea

Cyanuric acid is implied in connection to the 2007 pet food recalls, the contamination and wide recall of many brands of cat and dog foods beginning in March 2007. Research has found evidence that cyanuric acid together with melamine forms poorly soluble crystals which can cause renal failure

Cyanuric acid is classified as "essentially nontoxic."<1> The 50% oral median lethal dose (LD50) is 7700 mg/kg in rats.<9>

However, when cyanuric acid is administered together with melamine (which by itself is another low-toxicity substance), they may form extremely insoluble crystals,<10> leading to formation of kidney stones and potentially causing kidney failure and death -- as evidenced in dogs and cats during the 2007 pet food contamination and in children during the 2008 Chinese milk scandal cases.


Part of the problem, as I mention in the OP, is when the FDA starts allowing some of this and some of that in the food supply, you can end up with new combinations of toxins that should not be there.

And of course, not all adults have the same renal function. Many have compromised kidneys or take nephrotoxic drugs (like chemotherapy) or have diabetes. Or maybe they drink a quart of powdered milk a day instead of a pint, and they also eat a bunch of pork that is fed melamine scrap and that same person is taking cis-platinum for cancer.

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McCamy Taylor Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 06:53 PM
Response to Original message
23. More about Archer Daniel Midland's contribution to the melamine problem.
http://dafadizi.net/dd/index2.php?option=com_content&do_pdf=1&id=38

Note that "Roughage Buster" contains cyanuric acid the other chemical you need in animal and pet feed for melamine to cause kidney stones and renal failure. Basically this is a non protein nitrogen source added to animal (cow) feed in the US legally.

http://www.answers.com/topic/cyanuric-acid

Here you can read about how cyanuric acid is formed. Note that the same chemical reaction creates ammeline and melamine if the temperature is allowed to go higher.

No word about the purity of the cyanuric acid which ADM uses in its animal feed supplements, however if the manufacturers of animal feed use Roughage Buster than toss in some melamine scrap or use some adulterated protein with melamine you get a toxic mixture.
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eppur_se_muova Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 07:34 PM
Response to Original message
24. Thanks for frequent use of the word ADULTERATION. We need to remember this is DELIBERATE addition of
Edited on Mon Nov-17-08 07:35 PM by eppur_se_muova
foreign substances, not contamination due to carelessness. We haven't seen anything like this in this country since the days before the FDA was created in response to muckraking articles exposing the horrendous practices of food processors and outright scam artists. Now we're back to square one, because the producers -- and the scam artists -- got outsourced beyond the reach of American regulation.
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eppur_se_muova Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 07:55 PM
Response to Original message
25. Formoguanidine is rather unlikely to be formed accidentally.
The manufacture of 'formoguanidine' requires reaction with hydrogen gas, H2, over a metal catalyst. Such conditions are not encountered outside of manufacturing plants and laboratories. It is conceivable that some metabolic process could result in a similar reduction, but it doesn't seem all that likely. It seems like a good precaution to look for formoguanidine, but negative results wouldn't be at all surprising.
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McCamy Taylor Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Nov-17-08 09:09 PM
Response to Reply #25
26. Thanks! Would there be enough metal in raw coal and could enough H2 be liberated to
to cause this reaction if the melamine scrap came from coal? I know that they are trying to make hydrogen from coal, but would an ordinary coal to melamine/urea/other chemical process use the temperature and pressures required? And would the kinds of metals needed for a catalyst be found in Chinese coal?

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eppur_se_muova Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 06:34 PM
Response to Reply #26
29. Exceedingly unlikely. Usually platinum metals, at best, nickel is necessary. nt
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tom_paine Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Nov-18-08 07:18 AM
Response to Original message
27. Are you joking? Of course the Bushie FDA has taken action.
Edited on Tue Nov-18-08 07:21 AM by tom_paine
1) In accordance with the Bushie Mission of protecting the Wealthy 0.01% and their Corporations from the American People, this "investigation" has been given to the same Bushies who tanked the anthrax investigation, or their kissin' spiritual cousins over at Bushie EPA.

2) In accordance with the Bushie Mission of protecting the Wealthy 0.01% and their Corporations from the American People, even now the relevant documents are being shredded or, where possible, altered.

3) In accordance with the Bushie Mission of protecting the Wealthy 0.01% and their Corporations from the American People, any honest EPA employees, if they haven't been harassed and given false bad performance reviews so that they are now in other work, are being shut out and being given their tails to chase, lest they take too much of an interest in Bushie Activities.

I am sure if there are any honest employees left at the EPA, they now know well to keep their honesty hidden, lest they be targeted by Loyal Bushies for harassment, false bad performance reviews, and unjust firing.

4) In accordance with the Bushie Mission of protecting the Wealthy 0.01% and their Corporations from the American People, all leadership positions in this "Investigation of Bushfriends" (soon to be tanked like the Anthrax Investigation f Bushfriends was) are occupied by Loyal Bushies with absolutely no regard for the rule of law and who will be happy to serve their Bushie Masters as they did in the Anthrax Investigation where the Bushfriend who did it is not only walking free, but as the Nazis used to do, a corpse was put up for the idiots to point at as "perpetrator".


"The corpse did it." An old authoritarian trick used long before the Bushies were in their more primitive and violent Nazi form.
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eowyn_of_rohan Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Nov-18-08 07:51 AM
Response to Original message
28. Chinese MPC is even added to our dairy products
Chinese powdered milk and Milk Protein Concentrate (MPC) are used in MANY of the foods produced in the USA

"Wisconsin dairy cooperatives and other cheese plants will continue to source raw milk from neighboring states as well as source nonfat dry milk, condensed skim milk and liquid MPC for standardization of milk for cheese making."
By Bob Cropp
Professor Emeritus
University of Wisconsin
Madison, Wisconsin

I posted this a few weeks ago, but here it is again for those who didn't see it:

Milk Protein Concentrate (MPC)— Consumers Must Be Warned
By Brenda Cochran and Donna Hall, dairy farmers in PA Nov. 2006 (TWO YEARS AGO)

...The fact that MPC is a powder that comes from diverse foreign countries makes it impossible to verify its source since it might be mixed together to obtain certain levels of protein, and no one using it wants to certify its origin or its safety or nutritional analysis. Some of the countries sending MPC to the U.S. for use in our food supply include India, Russia, and China, all nations where questionable health issues in the past have included radiation contamination, chemical pollution, and disease factors. India, one of the major exporters of MPC, has free-ranging, garbage-eating water buffalo as a chief source of its milk protein concentrate. Shipment and transhipment can easily hide the fact that MPC originates in foreign countries routinely challenged by outbreaks of Mad Cow Disease, Hoof and Mouth Disease, brucellosis, and many other serious diseases. Don’t count on U.S. Customs to watch out for consumers since less than two percent of any imports is being inspected. Global terrorism underscores the need to maintain safe, domestic milk supplies.


Why is FDA continuing to allow MPC use in our food even after the agency warned Kraft, the biggest user of MPC, to stop using it in their Kraft American Singles? Why are the nation’s largest dairy co-operatives, including Land O’Lakes and Dairy Farmers of America (DFA), also the biggest importers of MPC? This MPC causes a “created surplus” in dairy products that is used to drive down the price farmers receive for domestic milk. The ensuing low milk prices are driving thousands of dairy farmers out of business every year making consumers increasingly dependent on imported dairy products while they are unaware of the problem with MPC in our food supply.

http://www.familyfarmdefenders.org/pmwiki.php/MilkProte...

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