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marmar Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:11 PM
Original message
Puff-a-Day Marijuana Dose Helped Older Rats Remember
Light 'em if you got 'em. :smoke:



from Bloomberg:



Puff-a-Day Marijuana Dose Helped Older Rats Remember (Update1)

By Rob Waters

Nov. 19 (Bloomberg) -- A daily puff of a compound like marijuana, the plant blamed for ruining potheads' recall, might help maintain memory in old age, researchers who tried it on rats reported today at a neuroscience meeting.

Elderly rats remembered their way around a swimming pool and could find hidden resting spots after Yannick Marchalant and his colleagues at Ohio State University gave them a compound that mimics the effect of marijuana on the brain's cannabis receptors. The marijuana-like drug, known as WIN-55212-2, spurred new brain cell growth and reduced inflammation, the researchers said.

Inflammation in the brain may be linked to the development or progression of Alzheimer's, a progressive disease that destroys brain cells, disrupting the memory and cognitive capacity of some 4.5 million Americans, some scientists believe. Marchalant and his colleagues have been hunting for drugs to reduce inflammation.

``We used a low dose because we didn't want to give them a drug that tried to save their memory while we're also causing psychoactive effects,'' Marchalant said in a telephone interview yesterday. ``The dosage of WIN would be like giving one puff a day and not a whole joint.''

Marchalant and his team reported their results today at the Society for Neuroscience meeting in Washington, D.C. In the study, they first caused inflammation in the brains of young rats, which they could measure by looking at the activity of anti-inflammatory cells. Then they injected rats with WIN and saw that it reduced the activity of the inflammation-fighting cells. .......(more)

The complete piece is at: http://www.bloomberg.com/apps/news?pid=20601124&sid=aRiIRLxtgAcE&refer=home




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Sanity Claws Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:14 PM
Response to Original message
1. Remember what?
Where the Doritos are?
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Dukkha Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:16 PM
Response to Reply #1
4. how big their claws are
Edited on Wed Nov-19-08 08:16 PM by Neo
wow man, they're like huge!
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dixiegrrrrl Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 11:41 PM
Response to Reply #1
20. when to leave a sinking ship.
slightly smarter than Lieberman, it turns out.
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Demobrat Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:14 PM
Response to Original message
2. What the article doesn't tell you is
how long it took the rats to graduate to heroin.
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4_TN_TITANS Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Nov-20-08 03:21 PM
Response to Reply #2
21. Duzy....
It seems like reports about the benefits of pot come out daily now. Thank God states are waking up to the truth, even if the Fed continues to ignore it. Didn't I read that Obama made a statement vowing to end repression or manipulation of scientific data? How about an administration handing out anti-pot literature that is blantantly false?
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Fed_Up_Grammy Donating Member (923 posts) Send PM | Profile | Ignore Wed Nov-19-08 08:14 PM
Response to Original message
3. As an old broad------it sounds good to me. What's the date???? LOL
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Bolo Boffin Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:18 PM
Response to Reply #3
6. It's Take a Toke Day. You're just in time. :) n/t
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bleever Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:16 PM
Response to Original message
5. Love me some good science.
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mucifer Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:23 PM
Response to Original message
7. hmmmm I'm an older rat.
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tosh Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:28 PM
Response to Original message
8. "Light 'em if you got 'em. "
:cry:
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rucky Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:29 PM
Response to Original message
9. Is there anything the herb can't do?
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wildbilln864 Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:31 PM
Response to Original message
10. This reminds me of this...
Edited on Wed Nov-19-08 08:31 PM by wildbilln864
article.
"However, researchers found that cannabinoids promoted generation of new neurons in rats' hippocampuses.
....Hippocampuses are the part of the brain responsible for learning and memory, and the study held true for either plant-derived or the synthetic version of cannabinoids. "
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meow2u3 Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:32 PM
Response to Original message
11. Let's set the pot smoking age to 65!!!
Weed: coming to a nursing home near you. :rofl:

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OmmmSweetOmmm Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 11:33 PM
Response to Reply #11
17. 57, please please please??????
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Neshanic Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:34 PM
Response to Original message
12. But there is a marked increase in Cheese Nips munchies consumption.
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kimmylavin Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:39 PM
Response to Reply #12
13. :)
I've always said that if Frito-Lay and Hostess get behind legalization, the thing's a done deal. :)
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Neshanic Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:43 PM
Response to Reply #13
15. You are so correct on that. Adding Keebler it would pass faster than a bailout.
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orleans Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 08:41 PM
Response to Original message
14. ERIC HOLDER WILL PUT THOSE "DIRTY RATS" IN PRISON!
"Holder said he hopes to discourage some of that activity by being tougher on marijuana crimes. New guidelines should be in place by the end of the month, he said, noting that the District could learn from New York's "zero-tolerance" policy. There, crime plummeted when police aggressively enforced quality-of-life crimes, including panhandling and public drinking, which gave officers an opportunity to check for drugs, guns and outstanding warrants.

"Holder also proposed, in a December 1996 Washington Times interview, to impose mandatory minimum sentence of 18 months for any sale.

"While it's not clear if Holder's views have changed in the intervening 12 years, the question deserves attention in his confirmation hearings.


http://www.dailykos.com/story/2008/11/19/73027/712/665/663446

he'd go after barack for smoking dope too--if barack wasn't about to become president and give whittle eric his new job!

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Berry Cool Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 11:31 PM
Response to Original message
16. The article says the older rats were able to recall past events in surprisingly specific detail.
They were able to recite set lists from decades-old Dead concerts from memory.
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RagAss Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 11:35 PM
Response to Original message
18. How great would it be if the elderly actually pushed hard for legalization !
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Blue_In_AK Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Nov-19-08 11:40 PM
Response to Original message
19. I KNEW it all along.
The herb is good for you. :smoke: :hippie:
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