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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 07:24 AM
Original message
Shortage of Critical Commodities Seen Already - Important info for anyone that takes medications.
After reading this post from TwixVoy

http://www.democraticunderground.com/discuss/duboard.php?az=show_mesg&forum=389&topic_id=5119304&mesg_id=5119304

I found this important information. Everyone who takes medicine on a regular basis should know about it:

February 11, 2009

Shortage of Critical Commodities Seen Already
by Marygwen Dungan

http://www.safehaven.com/article-12578.htm

Maybe you thought that less trade with China would mean fewer choices of lawn gnomes at Walmart this summer. And since you've recently sworn off, who cares anyway. Turns out China is also a leading provider of the raw materials used to make critical pharmaceutical drugs. We'll have fewer of those too and, in some cases, none at all.

What inspired me to write about this subject was the predicament of a friend in pain management. Last week a Wegmans pharmacy ran out of OxyContin® and several other prescription medicines. Customers were told that Wegmans' supplier did not have the ingredients to make several medicines and did not know when they would have them. Wegmans isn't a mom-and-pop corner store with no buying power. It's a 71-store chain on the east coast, is one of the largest private companies in the US and had sales of $4.8 billion in 2008. The active ingredient of OxyContin® is thebaine, an alkaloid compound distilled from opium. By law, it cannot be stored so each year's crop size is determined by expected sales. However, it's only February so the shortage in the US is not due to Asian exporters' supplies having run out.

The shortage of leucovorin, a generic used in the treatment of colon cancer, is so acute that many cancer patients are receiving lower-than-prescribed dosages or none at all. According to suppliers, the shortage is due to "manufacturing" delays. In an interview with Forbes, Michael Katz, chair of a committee of patients that advises the Eastern Cooperative Oncology Group (ECOG), said, "I've never heard of anything like it," nor had any of the doctors in the group. There is a fear that shortages will occur more frequently with generic drugs because the margins are so thin. Leucovorin is also called folinic acid, which is derived from vitamin B and, like most vitamins, vitamin B comes from China.

There is also a worldwide shortage of acetonitrile, a critical chemical ingredient used in the purification of pharmaceutical compounds. Acetonitrile is a by-product of the automotive industry and is in short supply due to the worldwide slowdown in that industry, which, in turn, has caused chemical production facilities around the world to close.

Going forward, a number of factors will influence the availability of life-saving medicines and other critical commodities.

Supply disruptions: The majority of growers and producers of the raw materials for drugs are in Asia. You remember the cliff dive of the Baltic Dry Index last year. It was a reflection of severe disruptions in international trade, which, in large part, was caused by the unwillingness of banks to accept letters of credit. This could be the reason for the shortages of opium distillates, vitamins and other raw materials, which are showing up in US pharmacies now.

Profitability and production stoppages: Indian pharmaceutical companies have stopped manufacturing some unprofitable drugs and they threaten to cut back on more. Their profits have been eroded by the fall in value of the rupee, which has raised their procurement costs for both packaging materials and bulk purchases of raw materials from China.

Distribution: Trucking companies across the country are both cutting back on routes and closing due to less business and higher costs. This reached crisis proportions during the gas price spike last spring and summer and is continuing due to reduced demand for hauling. Bankruptcies were up more than 118% by the second half of 2008. In a Reuter's interview, industry consultant Fred Crawford said he expects the acceleration of bankruptcies seen in the second half of 2008 to continue this year.

If demand for medicine decreases in a depression, it's not because people aren't sick. In fact, more people are sick, but they can't afford medical care. If you've come across the crisis-preparedness list of 100 Things that Disappear First, you know that drugs are at the top of the list. Well, we are in a crisis, we are ill-prepared and, sure enough, medicines are disappearing.

..........

This is very important to consider for those chronically ill patients like my son with Progressive MS who need to have drugs to live with any quality of life that may be left for them. I hope and pray this is taken care of soon and should be a high priority to those in power.

:pals:
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madokie Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 07:27 AM
Response to Original message
1. The drug part worries me
I take a drug that I can tell from one prescription to the next is difference most times. hydrocodone
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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 07:28 AM
Response to Reply #1
2. Very good point - I also am concerned about the quality. No easy answers - n/t
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jeff30997 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 07:31 AM
Response to Original message
3. "pharmacy ran out of OxyContin"
All they have to do is go to Limbaugh's home and the shortage will be over.

Sorry,it was stronger than me,I had to say it.:)

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SpiralHawk Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 07:39 AM
Response to Reply #3
5. "Smirk." - Rush 'DraftDodger' Limbaugh (R - Overpaid Propagandist)
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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 07:40 AM
Response to Reply #3
6. If it was only a shortage for those like Limbaugh who use it for "recreation" I would be joyous!
Unfortunately I have seen the utter bone chilling pain my son goes through and he doesn't take OxyContin, but I wouldn't blame him at all if he had to.

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Jamastiene Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 07:38 AM
Response to Original message
4. K&R
This isn't a good sign.

My aunt has already had to buy meds on the shelf because none of the local pharmacies are able to get the cream she uses to help prevent pressure wounds. The over the counter stuff isn't working either.
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conscious evolution Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 08:58 AM
Response to Original message
7. Interesting article.However,
did you look at the bio of the author?
At first glance she sounds neocon-ish.

Marygwen has worked in banking and securities for 25+ years. Her first job after the University of PA undergrad and Wharton grad was as an investment banker at Paine Webber. After a stint in international commercial banking, MG returned to Wall St. as a risk-arbitrage sales trader, initially working for Merrill Lynch.

For the last ten years MG has been a supervisory analyst and editor of institutional equity and economic research for several multi-national financial firms including Banco Santander, Credit Lyonnais and Fox-Pitt, Kelton, a subsidiary of SwissRe. She currently writes for BlownMortgage and contributes to other top-rated blogs. Personal interests include historic restoration and organic farming.


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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 12:32 PM
Response to Reply #7
10. I believe her information is backed by actual first hand experience.
So I may not agree with her politics but I am concerned about the information she has provided.
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conscious evolution Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 01:26 PM
Response to Reply #10
18. Normally,
I would look at an article like this as a disinformation campaign to create either a bubble of some sort or as a way to get speculators to start running up the price for the commodities in question.
If you consider how much of the present financial crises is the result of deliberate criminal acts it is easy to see how this could also be created crises.

To early to tell now,imo.

Question-Have you ever read any of her other stuff? And if you have read her articles before this what is your opinion on which side of the fence she is on?

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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 01:39 PM
Response to Reply #18
19. No I haven't but if you read the last paragraph in her blog it seems she is being realistic.
Quote:

"If demand for medicine decreases in a depression, it's not because people aren't sick. In fact, more people are sick, but they can't afford medical care. If you've come across the crisis-preparedness list of 100 Things that Disappear First, you know that drugs are at the top of the list. Well, we are in a crisis, we are ill-prepared and, sure enough, medicines are disappearing."

What she says can be verified. I found out everything she says in this blog is the truth.
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DireStrike Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-25-09 12:30 AM
Response to Reply #19
26. if CE is correct,
That paragraph would best fit under the "Even the devil can quote scripture" paradigm.

Just keep your eye on it. If it is a bubble-driving campaign, I don't think we are well equipped to recognize it as such.
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dysfunctional press Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 09:11 AM
Response to Original message
8. i take methadone daily for chronic pain...
when it becomes unavailable, it'll mean check-out time for me.
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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 12:44 PM
Response to Reply #8
13. I haven't seen anything about shortages for this so please just check this out.
I posted the following website that shows "some" shortages on some medications. I hope we can just be proactive and make sure we have some supplies to get by if there does become a problem.

Here it is:

http://www.ashp.org/DrugShortages/Current/

Take care :pals:
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csziggy Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 11:43 PM
Response to Reply #13
24. That site shows limited supplies of Hydrocodone, too
Which is the active ingredient in Vicodine, the pain med I take when I need it. Fortunately, I just refilled it and have a nearly full bottle. Plus I do not need every day and I take it as little as possible since it makes me so groggy.

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bluesmail Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 10:29 AM
Response to Original message
9. Either BigPharma is lying about the shortages, (why would they
be truthful now), or they're NOT seeing profits disappear. Remember who * pals around with, besides BigPharma there's BigOil...I question their real motives.
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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 12:40 PM
Response to Original message
11. I looked around and found this website: Drug Shortage Resource Center
Edited on Tue Feb-24-09 12:40 PM by 1776Forever
Drug Shortages from ASHP Drug Product Shortages Management Resource Center

http://www.ashp.org/DrugShortages/Current/

................

Looks like some of these shortages have been resolved. I hope this helps.
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PufPuf23 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 12:42 PM
Response to Original message
12. I take two Rx meds
Last year the pharmacy signed me up in a programs that reduced the costs by 75%.

In the last 2 months the costs of the two meds has dropped again. One of the meds before the program I paid over $90/mth and the same med was $21/mth initially and two months ago dropped to $9/mth. The other med I did not start until after the program and its price dropped about 60% at the same time. The pharmacist was even surprised.
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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 12:46 PM
Response to Reply #12
14. Glad to hear good news! n/t
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undergroundpanther Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 01:13 PM
Response to Original message
15. Shit
Edited on Tue Feb-24-09 01:35 PM by undergroundpanther
I hate the greedy,their criminality while key people who could have stopped it,who could have taken a risk chose not to,but instead enabled this situation..

Corporations and consumerism have made this world toxic.All the corporate wastes and pollutants, their chemistry and their by products,industry cutting corners to raise animals in ways that make us sick,if we eat them, and the people who let it happen even when they knew what the company was doing would hurt us all are part of why people are so sick..

Throw away lifestyle of Consumerism is killing us and this planet.Having our bodies subjected to countless chemicals and pollutants day after day, facing forces it is not made to survive like car accidents or industrial accidents, it takes a toll on our health.And medicines help us cope.

So we now have tons of medicines that have become REQUIRED to help people cope with life,to stop pain,fight cancer or help us from wanting to kill ourselves.We live in a toxic chemical stew.
We live in a toxic culture of malignant narcissism instead of social cohesion,we live in competition against each other instead of cooperation,for instance.
And the sad part is when life in a culture that is sick makes us sick, something has to give.

If we continue to let the 'insurance companies' bullies(ceos) politicians and "leaders" take all,as if their 'status' makes them better than you or I, we will not be able to get anything ,and those in pain,those with severe illness, disability or injury will die,while the only wealthiest will have access to life saving drugs.

There is something very wrong with society when rich people are spared going without while the many suffer and die in debt for the maintenance of the rich.
Maintaining the rich have caused so much suffering for so many,suffering they did not have to face.
But we face it so the rich could have it all..And now we pay again.The drugs some people need are as basic to their needs as food or water in helping them function.
Being denied pain medicine is cruel punishment,for severe pain it torture.I have neuropathy,caused by having chicken pox years ago.The pain has been so bad I have thought of suicide to stop it.But thankfully I had a painkiller to take.I do not take them often.but when I need them,I DO need them.

The rich who do not care about others suffering,because they NEVER had to care about anyone else,really. Allowing such over the top wealth top be in so few hands of the wrong sorts of people are the problem, the people I hate are 'charming, manipulating,cold,cruel ,evil hearted,ruthless assholes that with no guilt or shame. Bad people who will scheme,deny people needs, cause harm, and bully others to get what they want,like those bonuses and golden parachutes. I wish they'd be forced to stop taking too much from all of us or die.

Would anyone miss these monsters if they were gone?
http://www.cassiopaea.com/cassiopaea/psychopath3.htm
http://www.cix.co.uk/~klockstone/spath.htm
http://www.apsu.edu/oconnort/crim/crimtheory08.htm
http://www.angelfire.com/zine2/narcissism/malignant_narcissism.html
http://www.encyclopedia.com/doc/1P3-922926191.html
http://home.cc.umanitoba.ca/~altemey/
http://cqs.com/psycho.htm

One person's idea of what it would take to truly change the way things are..
http://www.buzzle.com/editorials/12-28-2005-85004.asp
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Wiley50 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 01:15 PM
Response to Original message
16. But the Afgans Have A Bumper Crop of Opium?
which is first turned into morphine base and then Heroin

Simply make Time release heroin available to replace Oxycontin

I'm a pain patient and have taken morphine daily and worn a fentanyl patch since 2003

I'm more worried about the availability of fentanyl patches than I am about morphine

There are hundreds of tons of extra morphine running around

It's time to end the War on Drugs!
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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 01:21 PM
Response to Reply #16
17. I thought of that too - What is the "trade" rules on that - anyone know?
I didn't know that this was used in medications but I am not surprised. One more reason for medical marijuana isn't it?
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Divine Discontent Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 06:09 PM
Response to Original message
20. k&r
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tblue37 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 11:16 PM
Original message
Self-delete: accidental dupe. nt
Edited on Tue Feb-24-09 11:19 PM by tblue37


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tblue37 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 11:16 PM
Response to Original message
21. Hmmmmm---I wonder whether this is why my pharmacy has had to
have me wait several days for my medicines sometimes lately. It has gotten so that I try to refill my meds earlier than I ordinarily would, just so I don't run out before I am able to get the new prescription filled.

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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 11:17 PM
Response to Reply #21
22. I don't think it would be unreasonable to try and get the 90 day supply.
Just in case?? I just did.

:shrug:
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alfredo Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-24-09 11:31 PM
Response to Original message
23. 100 items that disappear first.
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RamboLiberal Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-25-09 12:14 AM
Response to Original message
25. Article from Orlando Sentinel - MSM newspaper - Feb 9th
Edited on Wed Feb-25-09 12:18 AM by RamboLiberal
A drug shortage has been keeping many colon-cancer patients in Central Florida and nationwide from getting a medicine that boosts the effectiveness of their chemotherapy.

Supplies of the generic drug, leucovorin, have lagged since December, when one of its two manufacturers ran into production problems, according to the U.S. Food and Drug Administration. Local oncologists have been forced at times to change treatment regimens or give people lower doses than usual.

"They tell me that I need this to help my chemotherapy bind to the tumor better and shrink it," said colon-cancer patient Patricia DiFonzo, 65, of Casselberry. "This is a drug that a lot of people need. I just don't understand how this can happen. Who's minding the store?"

Leucovorin is one of 10 drugs in short supply nationally, according to information on the FDA's Web site. Others include the chemotherapy agent cisplatin and a patch for early-stage Parkinson's patients called Neupro.

http://www.orlandosentinel.com/orl-drug0709feb07,0,4639864.story

Periodic shortages of pain relief medications have caused problems in recent months for some area hospitals and the patients who rely on them.

On its Web site, the Food and Drug Administration reported the shortage of oxycodone immediate release tablets in 5, 15 and 30mg.

Erica Abbett, a spokeswoman for drugmaker Covidien, explained the shortage this way: "Currently there is an industrywide supply issue with oxycodone-related products. The situation is due to multiple factors, including two competitors' products being removed from the market because of recalls.

"Covidien has significantly increased our product output as a result of the supply issue, however we alone cannot meet the total demand for these products. We are working diligently to ensure that interruption of patient access to vital pain management products, like oxycodone, is minimized," Abbett said.

http://www.sbsun.com/news/ci_11761040

Information from FDA: http://www.fda.gov/cder/drug/shortages/#Current
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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-25-09 03:58 PM
Response to Reply #25
29. Thank you for this - It shows the information in the article can be verified - unfortunately.
I hope this is being looked at VERY closely!
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KakistocracyHater Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-25-09 01:22 AM
Response to Original message
27. And where did we get the raw materials in the 1980s?
I also have a problem that a key ingredient is relegated to a "byproduct" of the automotive industry, & their troubles are bottlenecking medicines. I would create a new industry then, for the sole purpose of making acetonitrile; also that opium "problem" in Afghanistan-I've said from day 1 all I see is morphine in those fields & codeine & genuine medical interests....so WHY hasn't anyone also thought of this?

There are jobs to be created here somewhere....oh wait, they might be called 'protectionist', keeping it within our borders. The test is to see what our leaders will do in the face of all this.
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SmileyRose Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-25-09 01:27 AM
Response to Original message
28. We got a Kaiser HMO letter telling us the blood pressure and osteoporosis meds are drying up
they said if the generics can't be gotten then they'll pay for the brand name to make sure we have our meds.
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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-25-09 03:59 PM
Response to Reply #28
30. Which blood pressure meds was it please? I just wondered as a lot of us take these.
Thank you for posting!
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SmileyRose Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-25-09 04:49 PM
Response to Reply #30
31. metoprolol - not the extended release kind.
osteoporosis med was the generic of Fosamax without the D vitamin in it (starts with an "A") - Alendronate or something similar.
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1776Forever Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-25-09 05:50 PM
Response to Reply #31
32. Thank you for the reply.
:hi:
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