"The real question is, how hard should we be looking for breast cancer?"

[babylonsister]

Raise your hand if you think women are over-treated.

Too Many Breast Cancers Diagnosed by Mammograms?
July 10, 2009 05:25 PM ET | Deborah Kotz


When it comes to breast cancer, there are certain dogmas that we accept as fact: First, a malignant tumor—allowed to grow unchecked—will eventually spread throughout the body and kill. Second, regular mammograms are a must for women over 40 to find every mass before it turns deadly. The trouble is, these "truths" aren't substantiated by scientific evidence. A new and somewhat shocking study out today shows that about 1 in 3 breast cancers detected on screening mammograms is overtreated. In other words, these malignancies wouldn't have caused symptoms or death in a woman's lifetime, according to research published in the British Medical Journal.

The study, reviewing data from women who began screening at age 50, specifically found that mammograms save 1 life for every 10 cancers that are diagnosed and treated unnecessarily. (Another study published three years ago measured 1 saved life for every 2 cancers unnecessarily treated.) What this means is that mammograms lead to far more unnecessary surgeries and chemotherapy treatments than saved lives. "The real question is, how hard should we be looking for breast cancer?" asks Gilbert Welch, a professor of medicine at the Dartmouth Institute for Health Policy and Clinical Research who wrote an editorial that accompanied the study. That's a toughie because most women wouldn't feel comfortable knowing that they might have a potentially deadly breast tumor lurking in their body undetected. And, as breast surgeon Susan Love previously told me, doctors aren't able to discern the deadly cancers from the benign ones.

Welch thinks that women need to make informed decisions when it comes to deciding whether to be screened with mammograms, rather than being told simply that the X-ray is lifesaving. The new study showed some compelling evidence, graphing incidence rates of invasive breast cancer over the decades, beginning before screening was initiated. If mammography screening were working to find troublesome breast cancer in women in their 50s, then the incidence of breast cancer should have dropped for women who were screened in their 50s and 60s and who were now hitting their 70s when comparing them to those in their 70s who were never screened. Instead, the incidence rates don't drop below the rate that would be expected if women never had screening in the first place. What this suggests is that mammograms find a lot of tumors that may never have been found otherwise or caused any problems.

This is very similar to the dilemma posed by prostate cancer, says Welch. Experts are now beginning to question the usefulness of PSA screening, given that autopsy studies show that invasive prostate cancer commonly occurs in men who die of something else.

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http://health.usnews.com/blogs/on-women/2009/07/10/too-many-breast-cancers-diagnosed-by-mammograms.html