read the side effects...well known side effects-for over a decade........
no wonder the current SSRIs are ineffective.larium was used in Iraq through 2004,and Afghanistan through 2009.
http://www.cbsnews.com/stories/2003/01/27/60II/main538144.shtml(from 2003)
“We had no way to know that this drug would be so powerful that it could alter his personality so much and damage him so much that he would, in fact, do that in some type of delusion or hallucination. That's what we didn't know,” says Linda Perry.
But Roche did know something about Lariam and suicide. Over the past year, two UPI reporters, Dan Olmsted and Mark Benjamin, unearthed internal documents. They show that by the time Chuck Perry killed himself, the company knew of at least seven suicides, and 13 suicide attempts, by people living outside the United States - all associated with Lariam. But nowhere in its product information was there any mention of the word suicide.
http://www.ahrp.org/infomail/0802/29.phpfrom 2002
United Press International (UPI) reporters, Mark Benjamin and Dan Olmsted, have conducted a 6 month investigation of the reports linking the antimalaria drug, Lariam to severe mental disorders--including violence and suicide.
http://www.upi.com/results.cfm?Keywords=lariam On May 21, UPI reported that "in thousands of pages of internal documents spanning a decade, Hoffmann-La Roche tracked increasing reports of suicides, suicidal behavior and other mental problems among Lariam users. A review of four years of reports filed to the FDA found 11 suicides attributed to Lariam, and one expert on drug side effects said he believes the number easily could be 100 times higher." Furthermore, *"A statistical analysis of FDA data, commissioned by UPI, indicates that Lariam users are five times more likely to report having mental problems that could lead to suicide than those taking a different drug -- the antibiotic doxycycline -- also used to prevent malaria."
http://www.upi.com/print.cfm?StoryID=20052002-054200-9601r http://marenostrum.org/buceo/medicina/malaria/indexi.htmfrom 1995
"Case reports have documented possible Lariam-associated neuropsychiatric reactions, and such reports have lead to a hesitancy among military in the USA to use weekly Lariam as the preferred prophylaxis," added J. L. Sanchez in the prestigious journal,The Lancet.
Lariam's effects include "acute brain syndrome," consisting of disorientation and mental dysfunction, and "psychiatric symptoms", such as acute psychosis, memory loss, confusion, hallucinations and behavioral abnormalities -- aggression, agitation, and hyperactivity. Although most of these psychiatric symptoms generally do not last more than 10 days after terminating use of Lariam, severe depression can persist up to nine months. "There is no explanation for these reactions," noted Hennequine.
http://www.leatherneck.com/forums/archive/index.php/t-10761.htmlfrom 2003
Sen. Dianne Feinstein wants the U.S. military to reassess its use of the anti malaria drug Lariam, prescribed to some troops in Iraq, because of what she calls "growing evidence about Lariam's dangerous side effects" and complaints by troops that it has damaged their health.
"Given the mounting concerns about Lariam as expressed by civilians, service members and medical experts about its known serious side effects, I strongly urge you to reassess the (Department of Defense) policy on the use of Lariam," the California Democrat wrote Defense Secretary Donald Rumsfeld in a letter dated Oct. 29.
In the short term, Feinstein said, the military should "immediately provide service members with information about Lariam's potential side effects," more closely monitor troops for problems and offer easy access to alternatives.
The Pentagon declined to comment on the letter. In the past, military medical officials have said that the drug has proven its worth and hasn't caused serious problems. "Our point of view is Lariam is a very useful medication in preventing a dangerous disease, and our experiences with it have been good," Virginia Stephanakis, a spokeswoman for the Army surgeon general's office, told United Press International earlier this year.
http://www.msnbc.msn.com/id/6947472/from 2005
Pogany is among the current or former troops sent to Iraq who claim that Lariam, the commercial name for the anti-malarial drug mefloquine, provoked disturbing and dangerous behavior. The families of some troops blame the drug for the suicides of their loved ones. Though the evidence is largely anecdotal, their stories have raised alarm in Congress, and the Pentagon has stopped giving out a pill it probably never needed to give to tens of thousands of troops in Iraq in the first place.