Could this excessive clotting situation be the key?

[ibegurpard]

It seems like it could be a major contributing factor in a lot of seemingly disparate symptoms and conditions that we keep encountering.

[elias7]

1. I think it's a piece...

Hypercoagulability does appear responsible for the stroke and some of the cardiac events seen -these are vascular issues, thromboembolic phenomenon, which is why those patients manifesting such issues are anticoagulated.

But, this appears separate from the cytokine storm of interleukins described in the folks with severe lung involvement/ARDS, which would be an inflammatory response. In some, perhaps, the inflammatory response activates the clotting cascade and maybe they are connected.

I don’t see a connection with the GI symptoms that some get, or with the influenza like symptoms of high fever, headache/body aches and lassitude.

Everyone’s immune system is behaving in variable fashion to the virus, maybe some it depends on viral load at time of exposure, maybe some depends on which mutation you have been exposed to. People are working this...

[kentuck]

2. Would it make a difference...?

If it was breathed into the lungs, or eaten with some food, or drank with some liquid? Would each of those actions affect a different part of the body?

[Bernardo de La Paz]

6. There is only evidence for infection by respiration. Have not heard a shred of evidence re eat/drink

Once in the body, it seems to go everywhere.

[Meowmee]

9. Yes it is transmitted fecally and orally as well like sars cov

https://www.medpagetoday.com/infectiousdisease/covid19/85315

I started out with gastro symptoms and a severe headache which I thought was a migraine.

[Bernardo de La Paz]

10. Thanks. I knew it had been found in feces, but TRANSMISSION is still unknown:

Have you been tested for the virus? Have you been tested for antibodies by a reliable test?

I'm guessing you have recovered from whatever it was, which would be very good news!

"It is a potentially important finding of relevance to the emergence of COVID-19 globally, but the exact extent of gastrointestinal transmission of the virus remains unclear," Hotez told MedPage Today.

He added that whether fecal oral transmission is common or uncommon therefore requires additional investigation

Presence in feces is not evidence of transmission.

[Meowmee]

18. Sars cov 1 was transmitted that way to family members, just think toilets etc.

No I have not recovered, 3 weeks in. I am isolating at home with double pneumonia and terrible back pain which seems to not improve ever. My c test was neg but doc says and I agree it is false neg. she says due to the pneumonia it could take a few weeks to fully recover. I think it is time for another x ray though due to the pain, but there are few places I can go and it is stressful. I am nearly out of the woods for severe stuff now hopefully assuming nothing else is going in. Pulse ox has been good through out. I am on several inhalers due to asthma worsening with the pneumonia,pain killers, non stop heating pad and rest as much as possible.

She feels none of the antibody tests are reliable yet so I will wait on that.

[Bernardo de La Paz]

19. Best wishes. You are in a tough spot, but you are strong and I have confidence you will become well.

[Meowmee]

20. Thanks💕 it is rough for sure but I am a fighter, just hope it starts to get better soon

[luvtheGWN]

11. I read an article the other day about younger Covid patients,

age range 20-45, dying of stroke-like symptoms. They had no underlying medical issues and their deaths took the docs by surprise.

This is one incredibly nasty virus, folks.

[Jamastiene]

3. Apparently, this virus is all over the place. Clots do seem to play a major role, but

this virus attacks so many organs from the brain all the way down to the toes, literally, and causes so much havoc in the human body, they are at a loss on what to do so far.

Here is one article I read that has some of the information. The second one is more in depth and has links to other articles as well.

https://www.sciencemag.org/news/2020/04/how-does-coronavirus-kill-clinicians-trace-ferocious-rampage-through-body-brain-toes

h/t to swag for this link:
https://nymag.com/intelligencer/2020/04/we-still-dont-know-how-the-coronavirus-is-killing-us.html

[kentuck]

4. That link is very informative!

Thanks!

[Lochloosa]

5. Kicking for these links. Thanks,

[sprinkleeninow]

7. Appreciate the info. in these links!

[TNNurse]

8. Any part of the body that would require blood flow would be affected by clotting.

So, yes.

[2naSalit]

15. +1

[SheltieLover]

12. Horrible!

WAPO had article on this, as did STATNEWS.

[no_hypocrisy]

13. I heard a medical theory is that clotting is the result of the lining of blood vessels

(veins and arteries) being destroyed by the Virus.

https://www.sciencemag.org/news/2020/04/how-does-coronavirus-kill-clinicians-trace-ferocious-rampage-through-body-brain-toes

https://www.globalhealthnow.org/2020-04/covid-19s-vascular-attack

[Igel]

16. It attacks anything with ACE2 receptors.

Meaning endothelial tissue.

Artery-wall linings, GI tract, airways ... Quite a successful means of infection.

[mopinko]

14. inflammation is at the root of most medical ills.

so, this thing setting off wide cytokine storms means inflammation everywhere in the body. i suspect most people who get really sick have some sort of underlying inflammation already. they likely dont even know it. nor do their docs.

my curiosity is getting a work out in all this. sigh. more shit i never wanted to know.

[crickets]

17. K&R for the post and the discussion.

[Meowmee]

21. I don't know if it is helping me but I am on eliquis due to a second dvt nt