Good news about AstraZeneca - could be as effective as the other vaccines

[flamingdem]

Link to tweet

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[Wounded Bear]

1. Is this one that has lessor storage requirements?

That would be nice.

[dchill]

2. Good news...

"...AZD1222, can be stored and transported at normal refrigerated temps of 2 degrees to 8 degrees Celsius (36 degrees to 46 degrees Fahrenheit) for at least six months.."

https://www.fiercepharma.com/manufacturing/astrazeneca-hopes-warmer-storage-needs-for-covid-19-vaccine-will-be-advantage-against#:~:text=AstraZeneca's%20COVID%2D19%20vaccine%20candidate,logistics%20leg%20up%20over%20a

[Wounded Bear]

3. Much easier logistics, TBS...

[LonePirate]

4. My brother is currently participating in a US trial of this vaccine.

He had his first shot a little over two weeks ago and he receives his second one in the middle of January.

He said the trial group is two-thirds vaccine and one-third placebo. He obviously doesn't know which group he is in but he seems to think he is in the vaccine group as his arm was sore for a day or two after the shot and he said his arm is never sore after a flu shot. Otherwise he has had no side effects. He's in his mid-40s and is very diligent about wearing a mask in public.

[crimycarny]

5. Awesome! And much easier (and cheaper) to mass produce

I read they already geared up their supply chain worldwide so that they can start immediate distribution. They plan to have 400 million doses for the US by early 2021 if approved.

The Johnson and Johnson COVID vaccine uses an approach that is very similar to AstraZeneca’s, so hopefully it will be just as effective. Unfortunately the J&J vaccine is lagging in approval as it’s still in Phase 3.

If we could get all 3 vaccines going ASAP (Pfizer, Moderna, AstraZeneca), maybe there’s hope we’ll turn the corner soon???

[Disaffected]

6. Yes!

And, as I understand it, we have capability to manufacture that type of vaccine here in Canada (lagging behind here because a previous Conservative government curtailed vaccine R&D).

This year is ending a lot better than it started!

[triron]

8. Great news for Canada.

[LisaL]

11. Astra Zeneca has not been approved in the US and likely won't be until US trials conclude.

NT

[crimycarny]

14. It could be as soon as February

https://www.politico.com/news/2020/12/14/more-vaccine-developers-fda-approval-445194

“The first efficacy readout of AstraZeneca’s vaccine could come in the second half of January, Slaoui estimated, and the company could potentially file for emergency use later in February.“

[triron]

7. I understand the per cent effectiveness depends on the dose.

Two vaccinations gives over 90% effectiveness.

[flamingdem]

9. Not sure if the extra 5% worries me

I might be more worried about the difference between vaccine types - the messenger MRNA vs the Adenovirus and what that means - right now not sure

[crimycarny]

16. Here is a good explanation of the difference of AstraZeneca vs Pfizer & Moderna

[LisaL]

10. That's not accurate.

They got 60% effectiveness with 2 doses when they used 2 full doses. They got 90% effectiveness when they used two doses with first dose being a half dose (but that was done on a small group of people).

[crimycarny]

15. The good news is the say it was 100% effective against severe COVID

So, if nothing else, it will reduce the severity of your symptoms even if it’s not able to completely protect against COVID.

[Disaffected]

12. Did they ever,

get that half-dose given by mistake issue sorted out (some of the phase 3 participants got only a 1/2 dose in error for the first shot and were paradoxically found to get better protection that those who received the correct, full dose)?

[flamingdem]

13. Here's something about the half dose

Link to tweet

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