Major study of Ivermectin, the anti-vaccine crowd's latest COVID drug, finds 'no effect whatsoever'

[LetMyPeopleVote]

The RWNJ sites are really pushing this quack cure. This medicine is for horse deworming

Link to tweet

Ivermectin, the latest supposed treatment for COVID-19 being touted by anti-vaccination groups, had “no effect whatsoever” on the disease, according to a large patient study.

That’s the conclusion of the Together Trial, which has subjected several purported nonvaccine treatments for COVID-19 to carefully designed clinical testing. The trial is supervised by McMaster University in Hamilton, Canada, and conducted in Brazil.....

Among the 1,500 patients in the study, he said, Ivermectin showed “no effect whatsoever” on the trial’s outcome goals — whether patients required extended observation in the emergency room or hospitalization.

“In our specific trial,” he said, “we do not see the treatment benefit that a lot of the advocates believe should have been” seen.....

The findings on Ivermectin are yet another blow for advocates promoting the drug as a magic bullet against COVID-19. Ivermectin was developed as a treatment for parasitical diseases, mostly for veterinarians, though it’s also used against some human parasites.

[lapfog_1]

1. Not surprised but it is too bad

It would be great to have a cheap available drug to fight this pandemic, one already tested in humans. Having a therapeutic to treat Covid would save untold suffering in the coming year or so, possibly longer.

In addition, let's not dismiss Ivermectin as ""just a horse de-worming drug", it has improved the lives of countless people in poorer nations around the world.


Discovered in the late-1970s, the pioneering drug ivermectin, a dihydro derivative of avermectin—originating solely from a single microorganism isolated at the Kitasato Institute, Tokyo, Japan from Japanese soil—has had an immeasurably beneficial impact in improving the lives and welfare of billions of people throughout the world. Originally introduced as a veterinary drug, it kills a wide range of internal and external parasites in commercial livestock and companion animals. It was quickly discovered to be ideal in combating two of the world’s most devastating and disfiguring diseases which have plagued the world’s poor throughout the tropics for centuries. It is now being used free-of-charge as the sole tool in campaigns to eliminate both diseases globally. It has also been used to successfully overcome several other human diseases and new uses for it are continually being found. This paper looks in depth at the events surrounding ivermectin’s passage from being a huge success in Animal Health into its widespread use in humans, a development which has led many to describe it as a “wonder” drug.

[roamer65]

3. Fenofibrate (Tricor)

https://www.birmingham.ac.uk/news/latest/2021/08/covid-licensed-drug-reduce-infection.aspx

https://www.pharmaceutical-technology.com/news/study-fenofibrate-covid-19/

I’m on max dose for high triglycerides.

Very well tolerated and very safe.

[Rstrstx]

7. Indeed. If it had been a miracle cure it would have been obvious months ago

This finding comes as no surprise, the Australians that first performed the experiment on the virus with Ivermectin noted it would take an insanely high amount in the body to come close to replicating the results they saw in the lab, well beyond what a human could tolerate.

I’ve heard Pfizer is working on a covid pill, it can’t come soon enough. Perhaps they need to work on a pill to fix stupid.

[RockRaven]

2. "FaKe NeWs!!!!!!1!!!1!!!!"

I heard an interview today with a reporter who covers MAGAts/RWNJs for a living (that's a helluva job) and he said that because:
A) this was a niche drug in humans the human pharmacy supply is limited, never mind convincing your doctor to write a prescription for it, and
B) sources of veterinary formulations (like Amazon and other online retailers) don't require prescriptions from human doctors,
means that of course these lunatics are having impassioned discussions online about whether the horse medicine or the sheep medicine is better, and how to convert the dosing to human weights, and the like.

And, FYI, the horse version is very popular, apparently. The journo speculated that was because it is apple flavored.

[LetMyPeopleVote]

6. "We won't get vaxed....Now if you'll excuse us, we're off to the farm store for animal medicine."

I have seen this drug promoted on the RWNJ sites.

Link to tweet

[LetMyPeopleVote]

4. I love that the scientific method was used in this study

The concept of controls and proper scientific methodology were used https://www.latimes.com/business/story/2021-08-11/ivermectin-no-effect-covid

The Ivermectin camp, as I reported earlier, is heavily peopled by anti-vaccination advocates and conspiracy mongers. They maintain that the truth about the drug has been suppressed by agents of the pharmaceutical industry, which ostensibly prefers to collect the more generous profits that will flow from COVID vaccines.

The problem, however, is that the scientific trials cited by Ivermectin advocates have been too small or poorly documented to prove their case. One large trial from Egypt that showed the most significant therapeutic effect was withdrawn from its publishers due to accusations of plagiarism and bogus data.

Nevertheless, the advocates have continued to press their case — without necessarily observing accepted standards of scientific discourse. During the symposium, Mills complained that serious researchers looking into claims for COVID treatments have faced unprecedented abuse from advocates.....

Mills said that his team’s Ivermectin trial was altered after advocacy groups complained that it was too modest to achieve the results they expected. The trial originally tested the results from a single Ivermectin dose in January this year, but was later changed to involve one daily dose for three days of 400 micrograms of the drug for every kilogram (about 2.2 pounds) of the patients’ weight, up to 90 kilograms.

Half the subjects received a placebo tablet. No clinical results were detected at either dosage, Mills said.

[Grins]

5. SOMEONE STUDIED THAT???

Was it Captain Obvious and his team of Neanderthals?