(Pre) COVID Organizing Pneumonia - hadn't head of this. Elder friend diagnosed last week.

[underpants]

I had not heard of this. A friend of the family, and older lady, was in ICU last week and doctors weren’t sure what was going on. One physician took a look at her X-ray and history (had COVID last year) and diagnosed her as having, as I heard it called, pre-COVID Organizing Pneumonia.

She’s out of the hospital now and doing better. She was prescribed steroids which seem to be working.


SARS-CoV-2 organising pneumonia: ‘Has there been a widespread failure to identify and treat this prevalent condition in COVID-19?

https://bmjopenrespres.bmj.com/content/7/1/e000724

Abstract
Reviews of COVID-19 CT imaging along with postmortem lung biopsies and autopsies indicate that the majority of patients with COVID-19 pulmonary involvement have secondary organising pneumonia (OP) or its histological variant, acute fibrinous and organising pneumonia, both well-known complications of viral infections. Further, many publications on COVID-19 have debated the puzzling clinical characteristics of ‘silent hypoxemia’, ‘happy hypoxemics’ and ‘atypical ARDS’, all features consistent with OP. The recent announcement that RECOVERY, a randomised controlled trial comparing dexamethasone to placebo in COVID-19, was terminated early due to excess deaths in the control group further suggests patients present with OP given that corticosteroid therapy is the first-line treatment. Although RECOVERY along with other cohort studies report positive effects with corticosteroids on morbidity and mortality of COVID-19, treatment approaches could be made more effective given that secondary OP often requires prolonged duration and/or careful and monitored tapering of corticosteroid dose, with ‘pulse’ doses needed for the well-described fulminant subtype. Increasing recognition of this diagnosis will thus lead to more appropriate and effective treatment strategies in COVID-19, which may lead to a further reduction of need for ventilatory support and improved survival.

[carpetbagger]

1. My stepfather probably has this

In his 80s, vax x 2 early on, got a mild case last month. CT looks like crap a month later We're a bit worried since he's a chemist and spent his life huffing God knows what, but I'm hoping it's all covid rather than idiopathic pulmonary fibrosis. He's mostly better.

[Demovictory9]

3. chem labs do smell weird. hope he recovers

[carpetbagger]

4. Thanks

[abqtommy]

2. There's a mixed response in patients with covid pneumonia treated with steroids.

"Steroids aren't risk-free, however. They can have side effects, and they could do more harm than good in patients with milder cases of COVID-19."

Read more at:

https://health.economictimes.indiatimes.com/news/industry/steroids-cut-covid-19-death-rates-but-not-for-everyone-heres-who-benefits-and-who-doesnt/87303871