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Celerity

(53,778 posts)
Fri Sep 26, 2025, 07:41 AM Sep 2025

AI just created a working novel genomic virus. The U.S. isn't prepared for that.

Last edited Fri Sep 26, 2025, 10:59 AM - Edit history (1)

A stunning scientific accomplishment brings both great promise and great risk.

https://www.washingtonpost.com/opinions/2025/09/25/artificial-intelligence-advance-virus-created/

https://archive.ph/i2bSJ



We’re nowhere near ready for a world in which artificial intelligence can create a working virus, but we need to be — because that’s the world we’re now living in.

In a remarkable paper released this month, scientists at Stanford University showed that computers can design new viruses that can then be created in the lab. How is that possible? Think of ChatGPT, which learned to write by studying patterns in English. The Stanford team used the same idea on the fundamental building block of life, training “genomic language models” on the DNA of bacteriophages — viruses that infect bacteria but not humans — to see whether a computer could learn their genetic grammar well enough to write something new.

Turns out it could. The AI created novel viral genomes, which the researchers then built and tested on a harmless strain of E. coli. Many of them worked. Some were even stronger than their natural counterparts, and several succeeded in killing bacteria that had evolved resistance to natural bacteriophages.

The scientists proceeded with appropriate caution. They limited their work to viruses that can’t infect humans and ran experiments under strict safety rules. But the essential fact is hard to ignore: Computers can now invent viable — even potent — viruses.

snip

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AI just created a working novel genomic virus. The U.S. isn't prepared for that. (Original Post) Celerity Sep 2025 OP
A nightmare scenario that I hadn't thought of. Swede Sep 2025 #1
This is REALLY BAD NEWS. FalloutShelter Sep 2025 #2
You know, when selfish people start creating their own realities... haele Sep 2025 #4
Others had already considered the possibility, but they don't have a solution, either. highplainsdem Sep 2025 #8
AI is the devil. Scrivener7 Sep 2025 #3
Time to purchase that remote off-grid property. harumph Sep 2025 #5
Hope you don't need a mortgage to do that Captain Zero Sep 2025 #9
"The scientists proceeded with appropriate caution." OldBaldy1701E Sep 2025 #6
They can just invoke the lysine contingency Orrex Sep 2025 #12
Or, just keep them all in San Diego. (n/t) OldBaldy1701E Sep 2025 #35
As with every tool invented by man this is a 2 way street Cheezoholic Sep 2025 #7
It isn't "a 2-way street" when it requires the theft of the world's intellectual property to work. It isn't highplainsdem Sep 2025 #10
I get what youre saying but still, it is only a tool. HiFi cassette tape recorders are a modern example Cheezoholic Sep 2025 #32
I would disagree. Eko Sep 2025 #34
And perhaps those yin yang's inevitably end in a civilization destroying itself. paleotn Sep 2025 #13
Your're right. Civilizations destroying themselves is probaly the most likely solution to Fermi's Paradox Cheezoholic Sep 2025 #33
Inevitable. Train the algorithm on digital viruses and how they're created. paleotn Sep 2025 #11
This article is about bio viruses, not computer 'digital' viruses. Celerity Sep 2025 #16
reading, not skimming is better. paleotn Sep 2025 #28
Let's just automate everything, including our deaths ... aggiesal Sep 2025 #14
The Jackpot Renew Deal Sep 2025 #15
I thought there would be a second season? JanMichael Sep 2025 #21
In February 2023, Amazon Prime Video renewed the series for a second season. On August 18, 2023, the second season of Celerity Sep 2025 #30
The potential for both good and bad exist here but all this is doing is helping speed what was already being done up. cstanleytech Sep 2025 #17
Anyone using AI for cancer research? KS Toronado Sep 2025 #18
What could possibly go wrong orangecrush Sep 2025 #19
"viruses that can't infect humans"... until one can CaptainTruth Sep 2025 #20
One of Science Fiction's greatest fears is a virus that wipes out humanity. patphil Sep 2025 #22
I wrote a paper on this in my Microbiology class many, many years ago. berniesandersmittens Sep 2025 #23
Dystopia Hekate Sep 2025 #24
No country is ready for that. Martin68 Sep 2025 #25
Great job humans! Have we reached peak dystopia yet? LymphocyteLover Sep 2025 #26
Time and space are infinite. multigraincracker Sep 2025 #27
A. I. Is the devil IA8IT Sep 2025 #29
Oh... Cirsium Sep 2025 #31

Swede

(38,437 posts)
1. A nightmare scenario that I hadn't thought of.
Fri Sep 26, 2025, 07:47 AM
Sep 2025

Just add it to the dozens that are already out there. The Fermi Paradox is getting understandable.

haele

(15,110 posts)
4. You know, when selfish people start creating their own realities...
Fri Sep 26, 2025, 08:05 AM
Sep 2025

Those realities don't just affect the people creating them...

"Oops, did I do that?" Is on the headstone of every rich man who also thought he was a Great Man.

Playing or speaking for God is the greatest Blasphemy.

highplainsdem

(60,194 posts)
8. Others had already considered the possibility, but they don't have a solution, either.
Fri Sep 26, 2025, 08:54 AM
Sep 2025

All too many of the people behind AI are both foolish and reckless, motivated by greed and/or delusions, especially the delusion that if they develop superintelligent AI first, then that godlike AI will out of gratitude help the humans who developed it become immortal and godlike as well. And with that goal in mind, they don't care how much harm AI causes in the meantime.

Idiots.

OldBaldy1701E

(10,278 posts)
6. "The scientists proceeded with appropriate caution."
Fri Sep 26, 2025, 08:07 AM
Sep 2025

GODS, how many times are we going to read this and say, "Yeah, that will work out just fine."

Let's show the machines how to kill us and hope they don't decide that we deserve to be killed.

Nice.

Cheezoholic

(3,542 posts)
7. As with every tool invented by man this is a 2 way street
Fri Sep 26, 2025, 08:10 AM
Sep 2025

Creation of bad viruses or creation beneficial bacteria or even a virus that can specifically target things like cancer cells. Yes it may seem like fantasy but it's coming and fast. As the article states, we're not ready. But then again, in our current state, we're not ready for an already naturally occurring novel virus that is most certainly lurking in areas where humans haven't frequented but could be released as we encroach into these ancient biological ecosystems. Yin Yang certainly applies here.

highplainsdem

(60,194 posts)
10. It isn't "a 2-way street" when it requires the theft of the world's intellectual property to work. It isn't
Fri Sep 26, 2025, 09:12 AM
Sep 2025

a 2-way street when it dumbs down users, damages the environment and increases wealth and power inequality. It has very few pluses, nowhere near enough to balance the minuses, and even those pushing AI admit it might destroy humanity.

Cheezoholic

(3,542 posts)
32. I get what youre saying but still, it is only a tool. HiFi cassette tape recorders are a modern example
Fri Sep 26, 2025, 04:34 PM
Sep 2025

I can remember artists and record companies, radio screaming that they offered a way to "steal" artists and companies "intellectual" property by enabling people to just buy one album and record 10 copies for their friends. Being able to make mix tapes on top of recording songs directly from radio allowed them to just turn off radio, and the obligatory commercials, and listen to multiple artists in one sitting in a very convenient and often "free" way. You could argue that just having a buddy record an album for you so you wouldn't have to go to the record store and thereby being bypassed the exposure to new and different artists and music could be a form of dumbing people down by limiting their exposure to new things. After all, that's pre-emptively what learning is at it's core.

This is a very crude comparison I admit but my point is every tool that man has invented is a 2 sided sword. I am by no means a fan of AI being used in ANY nefarious manner. I am also one that believes AI is NOWHERE near a thinking machine thats going to become aware and snuff us out.... yet. If anything, like the atomic bomb and the insane things we were going to do with it when we first built them (i.e. putting reactors in airplanes, blasting mines open with them etc.....), we hopefully will learn our lesson (usually the hard way) with AI and corral it, more importantly its nefarious uses, before it can do too much harm. The harm that AI has the potential to do to us is from the people wielding it. The great good and advancement that it has is from the people wielding it. It's not from AI itself. I like baseball unless someone uses a bat to beat someone else.

Every example above one can point to incredible GOOD things that came out of those tools, from PC's (Cassette tapes brought the home PC into being as the original hard drive), the myriad of medical and other very helpful things that came from a massively destructive device like the bomb. Once again crude examples but I think they get across my thought process here.

I think of it like the beginning of 2001 A Space Odyssey, when the first primitive human picked up a bone and smashed another one.
WE are the problem, or the solution, not the TOOL.

Respectfully

Eko

(9,826 posts)
34. I would disagree.
Fri Sep 26, 2025, 06:18 PM
Sep 2025

I'm on my third antibiotic in just over a year because the Lyme disease that I have has become resistant to them. Last time at the doctor I asked how many more antibiotics there were for us to use before it is resistant to them all and he said he would look it up for me. This part was pertinent to what I am talking about "and several succeeded in killing bacteria that had evolved resistance to natural bacteriophages." I hate most AI. I hate AI pics, videos, music, books, but the part that creates something that kills bacteria that has evolved resistance, that part I don't. I agree it is a 2 way street and it is being used for worthless, stupid and bad things and we should stop doing that. But for medicine? I think it is good.

paleotn

(21,634 posts)
13. And perhaps those yin yang's inevitably end in a civilization destroying itself.
Fri Sep 26, 2025, 09:26 AM
Sep 2025

As valid a solution to the Fermi Paradox as any.

Cheezoholic

(3,542 posts)
33. Your're right. Civilizations destroying themselves is probaly the most likely solution to Fermi's Paradox
Fri Sep 26, 2025, 04:42 PM
Sep 2025

I'd even say 99% of the time it's the solution (I'm no scientist obviously lol). Just from looking at ourselves I'd say thats the biggest reason there aren't rockets flying around every solar system with a Goldilocks planet. Its very hard for intelligence to progress beyond a certain technological level. I buy that 100%

paleotn

(21,634 posts)
11. Inevitable. Train the algorithm on digital viruses and how they're created.
Fri Sep 26, 2025, 09:22 AM
Sep 2025

Then tell it what you want and viola! It's all a matter of computing power. Ginormous server farms. And the waste of ginormous amounts of electricity. And this is the tip of the nefarious iceberg.

Time for a Butlerian Jihad? Maybe. As Barney Fife use to say....nip it. Nip it in the bud.

aggiesal

(10,567 posts)
14. Let's just automate everything, including our deaths ...
Fri Sep 26, 2025, 09:28 AM
Sep 2025

There should be a law.that when these AI generated viruses are created they need create a vaccine along with it.
This is like going to war without an exit plan, more deaths without a way to stop it

Renew Deal

(84,709 posts)
15. The Jackpot
Fri Sep 26, 2025, 09:36 AM
Sep 2025

From the TV show The Peripheral. It's really too bad it didn't get a second season

JanMichael

(25,725 posts)
21. I thought there would be a second season?
Fri Sep 26, 2025, 10:05 AM
Sep 2025

I guess I'll have to go out and get the books. I thought the first season was pretty spectacular.

Celerity

(53,778 posts)
30. In February 2023, Amazon Prime Video renewed the series for a second season. On August 18, 2023, the second season of
Fri Sep 26, 2025, 12:22 PM
Sep 2025
The Peripheral was scrapped due to the 2023 SAG-AFTRA strike.

https://variety.com/2023/tv/news/the-peripheral-canceled-amazon-season-2-renewal-1235700019/

cstanleytech

(28,245 posts)
17. The potential for both good and bad exist here but all this is doing is helping speed what was already being done up.
Fri Sep 26, 2025, 09:48 AM
Sep 2025

KS Toronado

(23,126 posts)
18. Anyone using AI for cancer research?
Fri Sep 26, 2025, 09:52 AM
Sep 2025

Since dumpie & Muskrat like to kill cancer research funds, how much of that money now sits in
their pockets?

patphil

(8,739 posts)
22. One of Science Fiction's greatest fears is a virus that wipes out humanity.
Fri Sep 26, 2025, 10:06 AM
Sep 2025

Someone will give AI the task of doing just that.
Welcome to Raccoon City.

berniesandersmittens

(13,096 posts)
23. I wrote a paper on this in my Microbiology class many, many years ago.
Fri Sep 26, 2025, 10:15 AM
Sep 2025

Since virus' were considered to neither be "dead" or "alive" at that time, I questioned if future nanotechnology advances could be used to edit and/or manufacture prions and proteins, creating a new virus.

I'll have to dig it back out. My professor told me it was a dark outlook on future technology, but could he not refute the possibility of such technology being produced. Of course, AI wasn't even in our vocabulary at the time. (At least not in my field of study)

This was 20 years ago. I've always believed that public knowledge of technology will come too late if it is used nefariously on the masses.

Yeah, I know. I've always had a paranoid streak.

multigraincracker

(37,027 posts)
27. Time and space are infinite.
Fri Sep 26, 2025, 10:36 AM
Sep 2025

So it is happening here and now. So it is happening in infinite places and in infinite time before and after now. So, no need to worry.

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