General Discussion
Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsRoad Rage? Blame your cat.
Road Rage Infection: Intermittent Explosive Disorder May Be Caused By Toxoplasmosis Gondii Parasite In The Human Brain
http://www.medicaldaily.com/toxoplasma-gondii-intermittent-explosive-disorder-road-rage-human-brain-379303
Millions of people suffer from rage disorder, a psychiatric condition marked by explosive episodes of unwarranted anger. But a team of researchers from the University of Chicago have discovered it really might not be their fault; theres a good chance a parasite living in their brains is causing their abnormal bouts of rage.
Roughly 30 percent of the human population is walking around with one of these parasites in their brains, and many don't know. According to the new study, published in the Journal of Clinical Psychiatry, people suffering from intermittent explosive disorder (IED) are twice as likely to be infected carriers. The single-celled parasite Toxoplasma gondii spends most of its life cycle inside a cat, but can infect people when they touch their mouths after changing their cats litter. The parasites are also transmitted through undercooked meat or contaminated water and usually reside as a harmless, latent infection.
For the study, researchers recruited 358 participants who were then evaluated for IED, personality disorder, depression, and other psychiatric disorders. Each participant was measured for characteristic traits, including anger, aggression, and impulsivity and then later tested for a latent toxoplasmosis infection. One third of the subjects were diagnosed with IED while another third were diagnosed with a psychiatric disorder other than IED. The last third had no adverse behaviors or notable diagnoses and served as a control.
It turns out, the group diagnosed with IED was twice as likely to test positive for a toxoplasmosis infection compared to only nine percent of the participants in the healthy control group. Twenty-two percent of those who had the characteristic anger disorder were infected by the parasite, while 16 percent of those with another psychiatric disorder were infected. But across the board, all of the participants whose blood tested positive for a toxoplasmosis infection scored significantly higher on scores of anger and aggression, whether or not they were healthy, diagnosed with IED, or another psychiatric disorder. Researchers arent sure if the parasite is directly causing aggression or IED, or if the two are simply correlated.
The Velveteen Ocelot
(115,683 posts)Since raiding the litter box for goodies is a common dog activity.
FLPanhandle
(7,107 posts)Apparently, they can't pass it to each other but only through cat litter box raids.
Eleanors38
(18,318 posts)One_Life_To_Give
(6,036 posts)Honest Judge, the worm made me do it.
Else You Are Mad
(3,040 posts)That when this parasite infects mice and rats, it causes them to actively seek out cats & causes them to be eaten.
whathehell
(29,067 posts)Just wondering.
surrealAmerican
(11,360 posts)How could you tell the difference?
whathehell
(29,067 posts)saying it manifests as passive aggression.
MADem
(135,425 posts)Once the diagnosis of toxoplasmosis is confirmed, you and your doctor should discuss whether treatment is necessary. In an otherwise healthy person who is not pregnant, treatment is not needed. Symptoms will usually go away within a few weeks. For pregnant women or people who have weakened immune systems, drugs are available to treat the parasite that causes toxoplasmosis
http://www.medicinenet.com/toxoplasmosis/page4.htm
What is the prognosis for toxoplasmosis?
The majority of people who get toxoplasmosis will have no significant long-term effects.
An infected fetus or infant has a variable prognosis, depending on the severity of the effects of the disease. The earlier the fetus is infected, the worse the prognosis. A woman carrying a severely affected fetus may experience a spontaneous abortion (miscarriage), and newborns may develop significant physical or mental problems.
Patients with compromised immune systems have a variable prognosis, depending on their response to treatment. Patients with HIV or long-term immune compromised states will need to continue treatment for life.
http://www.medicinenet.com/toxoplasmosis/page5.htm
Geez, this is depressing stuff, isn't it?
packman
(16,296 posts)I can blame the cat - The Toxoplasmic Defense
FLPanhandle
(7,107 posts)Hence their anger and hate?
madinmaryland
(64,931 posts)I'm owned by a cat and am not a tRump supporter.
Trailrider1951
(3,414 posts)This one?
[URL=.html][IMG][/IMG][/URL]
840high
(17,196 posts)frylock
(34,825 posts)awoke_in_2003
(34,582 posts)Doesn't take much to figure that out.
killbotfactory
(13,566 posts)so of course it's our cats
csziggy
(34,136 posts)Courtesy of Martin Shkreli!
The story of Daraprims huge price hike is part of a trend of exorbitant pharmaceutical pricing.
Julie Beck Sep 22, 2015
The drug company Turing Pharmaceuticals is under fire after a New York Times article published Sunday detailing how it raised the price of a toxoplasmosis drug by more than 5,000 percent after acquiring the drug in August. One tablet of Daraprim used to cost $13.50; now, after its acquisition by Turing, it costs $750 per tablet.
This could have significant effects on patients ability to afford treatment, though Turings CEO Martin Shkreli has said that Daraprim will be free for anyone who cant afford it. According to the Times, some hospitals may not be able to afford to keep the drug in stock, which could keep patients from getting treatment in a timely manner.
The Infectious Diseases Society of America (IDSA) and the HIV Medicine Association (HIVMA) wrote a letter to Turing earlier this month, asking them to reconsider the price increase.
Under the current pricing structure, it is estimated that the annual cost of treatment for toxoplasmosis, for the pyrimethamine component alone, will be $336,000 for patients who weigh less than 60 kilograms and $634,500 for patients who weigh more than 60 kilograms, the letter reads. This cost is unjustifiable for the medically vulnerable patient population in need of this medication and unsustainable for the health-care system.
http://www.theatlantic.com/health/archive/2015/09/daraprim-turing-pharmaceuticals-martin-shkreli/406546/
cwydro
(51,308 posts)But she's never had a cat.
I've always had cats. I've never had road rage.
awoke_in_2003
(34,582 posts)after changing the litter box
cwydro
(51,308 posts)So no litter box required.
But yes, I do wash my hands a lot!
GoCubsGo
(32,080 posts)I blame the idiots on the road. Worst. Drivers. Ever.