'The Doctor Who Fooled the World' - Book review
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Brian Deer, an award-winning reporter for the Sunday Times of London, whose “The Doctor Who Fooled the World” recounts his 14-year investigation of Andrew Wakefield, the former physician who launched the modern antivaccination movement with his claim that the three-in-one measles, mumps and rubella (MMR) vaccine causes a bowel syndrome in children that leads to brain damage and autism.
Mr. Deer submits the facts candidly. In January 1994 a British woman claimed that the MMR vaccine had caused her son’s brain damage, and announced plans to sue the vaccine’s manufacturers. In February 1996 Mr. Wakefield began working with Richard Barr, an attorney who represented litigants in a class-action lawsuit against the vaccine producers. In June 1997 Mr. Wakefield registered for a patent on his own measles vaccine, as well as for treatments of both autism and inflammatory-bowel disease.
In February 1998 Mr. Wakefield co-authored a paper in the medical journal the Lancet that linked the MMR vaccine to autism. The paper described the biopsies Mr. Wakefield had conducted on 12 children with intestinal symptoms and developmental disorders, nine of whom were autistic. The authors concluded: “We did not prove an association between measles, mumps, and rubella vaccine and the syndrome described. Virological studies are underway that may help to resolve this issue.” In fact, virological studies had already been done in Mr. Wakefield’s own lab and the results were negative. But that didn’t stop Mr. Wakefield from announcing that the MMR vaccine “on the balance of probability” causes autism. He proposed that the three individual components of the vaccine be given at intervals of a year. Public panic ensued, immunization rates in the U.K. fell, and confirmed measles cases in Britain subsequently rose to 1,348 in 2008 from 56 in 1998.
As the evidence against Mr. Wakefield’s hypothesis mounted, and no labs were able to replicate his study, and the detection of the measles virus and the rate of intestinal disease were no greater in autistics, and more details about Mr. Wakefield’s personal and financial interests in discrediting the MMR vaccine came to the fore, and 10 of Mr. Wakefield’s 12 co-authors disavowed the study, and the U.K.’s General Medical Council struck Mr. Wakefield’s name from its register due to “serious professional misconduct,” in February 2010 the Lancet retracted the 1998 paper.
Thanks to Mr. Deer’s efforts, the case against Mr. Wakefield grew even graver. It turns out that 11 of the 12 children in the original study were litigants in the case against the MMR vaccine’s manufacturer, and that Mr. Wakefield was paid nearly £500,000 by Mr. Barr for his work (with payments billed through a company owned by Mr. Wakefield’s wife). Mr. Wakefield didn’t disclose any of this until Mr. Deer uncovered the conflict of interest. Worst of all, when Mr. Deer obtained the medical records of Mr. Wakefield’s subjects, he discovered that several of them had presented with symptoms of autism before they received the MMR vaccine—or so long thereafter that the association was “more unlikely than likely.”
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There is no evidence linking vaccines to autism. That Mr. Wakefield, now 63, remains a hero of the antivaxxer movement is a testimony to the power of belief and the psychology of anecdotal causality. Meanwhile, thanks to the antivaxxer movement, herd immunity in a number of communities has been breached, and once-eradicated communicable diseases are making inroads in compromised populations. Ironically, the unvaccinated children of antivaxxer parents are themselves protected by the vaccinated children around them. The danger is for those who, for medical reasons, cannot get vaccinated and are not surrounded by vaccinated people.
https://www.wsj.com/articles/the-doctor-who-fooled-the-world-review-vax-populi-11601238052 (subscription)
Reviewed by Mr. Shermer who is the publisher of Skeptic magazine, host of the “Science Salon” podcast and the author, most recently, of “Giving the Devil His Due.”
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