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Researchers identify key peptides that could lead to a universal vaccine for influenza and would…
http://www.soton.ac.uk/mediacentre/news/2012/jan/12_17.shtml[font face=Times, Serif][font size=5]Researchers identify key peptides that could lead to a universal vaccine for influenza and would activate alternative mechanisms of the immune system[/font]
Ref: 12/17
31 January 2012
[font size=3]Researchers at the University of Southampton, University of Oxford and Retroscreeen Virology Ltd have discovered a series of peptides, found on the internal structures of influenza viruses that could lead to the development of a universal vaccine for influenza, one that gives people immunity against all strains of the disease, including seasonal, avian, and swine flu.
…
Researchers discovered that the immune systems produced various types of T-cells (part of the immune system that kills both viral particles, and cells infected with viral particles). Notably, the T-cells responded to peptides associated with the internal structures of the influenza viruses.
Unlike the external structures of influenza virus, that mutates very rapidly and creates a new strain of virus most years, the internal structures change very slowly over a long period of time. These internal structures are found in all strains of influenza virus - thus, a vaccine that targets such peptides may provide immunity against all strains of influenza, including seasonal (yearly), avian (bird), and swine flu, for many years.
A vaccine against these peptides would activate the T-cell immune response – which is able to respond much more rapidly than vaccines that activate an antibody response.
…[/font][/font]
http://dx.doi.org/10.1038/nm.2612Ref: 12/17
31 January 2012
[font size=3]Researchers at the University of Southampton, University of Oxford and Retroscreeen Virology Ltd have discovered a series of peptides, found on the internal structures of influenza viruses that could lead to the development of a universal vaccine for influenza, one that gives people immunity against all strains of the disease, including seasonal, avian, and swine flu.
…
Researchers discovered that the immune systems produced various types of T-cells (part of the immune system that kills both viral particles, and cells infected with viral particles). Notably, the T-cells responded to peptides associated with the internal structures of the influenza viruses.
Unlike the external structures of influenza virus, that mutates very rapidly and creates a new strain of virus most years, the internal structures change very slowly over a long period of time. These internal structures are found in all strains of influenza virus - thus, a vaccine that targets such peptides may provide immunity against all strains of influenza, including seasonal (yearly), avian (bird), and swine flu, for many years.
A vaccine against these peptides would activate the T-cell immune response – which is able to respond much more rapidly than vaccines that activate an antibody response.
…[/font][/font]
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