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Related: About this forumThe African American Woman Who Helped Design of the Moderna Vaccine Is Fighting Vaccine Hesitancy.
This a news item in Nature:
This COVID-vaccine designer is tackling vaccine hesitancy in churches and on Twitter
Immunologist Kizzmekia Corbett helped to design the Moderna vaccine. Now she volunteers her time talking about vaccine science with people of colour.
It should be open sourced, but here are some excerpts:
Kizzmekia Corbett, an immunologist at the US National Institutes of Health (NIH), is one of the scientists who in early 2020 helped to develop an mRNA-based vaccine for COVID-19. Developed in collaboration with biotech firm Moderna of Cambridge, Massachusetts, the vaccine is now being distributed across the United States and elsewhere. And Corbett is taking on another challenge: tempering vaccine hesitancy by talking about COVID-19 science in communities of colour.
Corbett is one of many Black scientists and doctors who are doing this outreach, often virtually, in their free time. Researchers say its necessary to make scientific knowledge accessible in public forums, to ease health disparities.
In the United States, COVID-19 has affected Black, Native American and Latino American people at higher rates than white people, for reasons rooted in racism and historical segregation. At the same time, people in these groups are more wary of COVID-19 vaccines. In a December survey by the US Centers for Disease Control and Prevention, 46% of Black adults said they probably would not get vaccinated against the coronavirus SARS-CoV-2, compared with 30% of white respondents...
...Before the COVID-19 outbreak, Corbett was part of a team at the NIH in Bethesda, Maryland, and elsewhere, that was designing vaccines for other coronaviruses in collaboration with Moderna. The scientists mRNA technology delivers a piece of genetic code to a persons cells to create immune-stimulating virus proteins. When the outbreak began, the team mobilized to quickly identify the SARS-CoV-2 genetic sequence it would need to make a vaccine for COVID-19, which Moderna then produced...
...What was your role in designing a vaccine for SARS-CoV-2, and what was that like?
My contribution was helping to design the vaccine, leading the preclinical studies that informed the Phase I clinical trial and designing assays used for testing of clinical trial samples.
The quest in early January 2020 was to gear up. We started ordering all the things that we needed around animal experiments. We mapped out a plan. I started assigning roles to team members.
If you want to go fast in a pandemic, then messenger RNA (mRNA) is a shoo-in. It can be manufactured very quickly in very vast quantities, and its plug and play in that you can essentially just swap out the protein once you have the system down. We collaborated with Moderna so we could get the system down pat...
Corbett is one of many Black scientists and doctors who are doing this outreach, often virtually, in their free time. Researchers say its necessary to make scientific knowledge accessible in public forums, to ease health disparities.
In the United States, COVID-19 has affected Black, Native American and Latino American people at higher rates than white people, for reasons rooted in racism and historical segregation. At the same time, people in these groups are more wary of COVID-19 vaccines. In a December survey by the US Centers for Disease Control and Prevention, 46% of Black adults said they probably would not get vaccinated against the coronavirus SARS-CoV-2, compared with 30% of white respondents...
...Before the COVID-19 outbreak, Corbett was part of a team at the NIH in Bethesda, Maryland, and elsewhere, that was designing vaccines for other coronaviruses in collaboration with Moderna. The scientists mRNA technology delivers a piece of genetic code to a persons cells to create immune-stimulating virus proteins. When the outbreak began, the team mobilized to quickly identify the SARS-CoV-2 genetic sequence it would need to make a vaccine for COVID-19, which Moderna then produced...
...What was your role in designing a vaccine for SARS-CoV-2, and what was that like?
My contribution was helping to design the vaccine, leading the preclinical studies that informed the Phase I clinical trial and designing assays used for testing of clinical trial samples.
The quest in early January 2020 was to gear up. We started ordering all the things that we needed around animal experiments. We mapped out a plan. I started assigning roles to team members.
If you want to go fast in a pandemic, then messenger RNA (mRNA) is a shoo-in. It can be manufactured very quickly in very vast quantities, and its plug and play in that you can essentially just swap out the protein once you have the system down. We collaborated with Moderna so we could get the system down pat...
Dr. Corbett:
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The African American Woman Who Helped Design of the Moderna Vaccine Is Fighting Vaccine Hesitancy. (Original Post)
NNadir
Feb 2021
OP
WA-03 Democrat
(3,047 posts)1. Excellent!
Thanks for posting