Does anyone else have a problem with weed?

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137. (2008), Bullous lung disease due to marijuana. Respirology, 13: 122–127.

HII, S. W., TAM, J. D. C., THOMPSON, B. R. and NAUGHTON, M. T. (2008), Bullous lung disease due to marijuana. Respirology, 13: 122–127. doi: 10.1111/j.1440-1843.2007.01186.x


Background and objective: In contrast to the well-described effects of tobacco smoking upon pulmonary emphysema, with ∼15% of smokers being affected at the age of 65 years, the effects of marijuana smoking are rarely reported and poorly understood.

Results: High-resolution CT revealed asymmetrical, variably sized, emphysematous bullae in the upper and mid zones. However, the CXR was normal in four patients and lung function was normal in five.

Conclusions: Marijuana smoking leads to asymmetrical bullous disease, often in the setting of normal CXR and lung function. In subjects who smoke marijuana, these pathological changes occur at a younger age (approximately 20 years earlier) than in tobacco smokers.