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RainDog

(28,784 posts)
16. a study of patients with MS found no increase in dosage - i.e. no tolerance
Mon Dec 26, 2011, 01:26 AM
Dec 2011

Last edited Mon Dec 26, 2011, 03:32 AM - Edit history (1)

although, yes, everyone is different.

however, in a study that included 167 patients with MS, they reported less pain, less muscle spasms, and less bladder incontinence with use of cannabis.

These patients reported that they were able to control symptoms with the same dose of cannabis for a mean duration of 434 days without having to increase their dose. (Wade, Multiple Sclerosis 10:425-33, 2004)

Researchers suggest that this study demonstrates that marijuana does not lead to increased tolerance requiring increased doses of medication, unlike the conventional medications used to treat MS.

so, over more than a year, patients with MS reported no tolerance regarding cannabis for relief of their symptoms.

This is different than the recreational use of cannabis, of course, but other substances, like opioids, indicate that tolerance is an issue whether they are used for symptoms of an illness or for recreational use.

We really need to do more studies on cannabis, and ones that are not given funding only when trying to prove a negative about cannabis - which is the standard for the U.S. - iow, if you want to study cannabis, you have to present a study that attempts to show cannabis is bad, harmful, addictive, etc. etc.

People who claim you can find a study to back up anything ought to also recognize that there is an institutional and financial bias toward negative findings... which would tend to make the negative findings less valuable since there is an incentive other than inquiry for setting up a study that will report what the govt. wants to hear.

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0 members have recommended this reply (displayed in chronological order):

I saw that too and my reaction was exactly the same. Xicano Dec 2011 #1
Only a doctor can tell you how to live. cthulu2016 Dec 2011 #2
From my first taste fifty years ago, WHEN CRABS ROAR Dec 2011 #3
Woodward and Bernstein suggest that we follow the money Kennah Dec 2011 #4
Interesting that all of his staff use and he and his brother use and MindMover Dec 2011 #5
I have smoked pot on an almost daily basis for over 35 years. roody Dec 2011 #6
It is a myth. nt Mojorabbit Dec 2011 #7
Your experience is definitely your own as is everyone who uses substances of any kind..... MindMover Dec 2011 #10
Gosh That's an interesting site you have there. hootinholler Dec 2011 #14
About that NIH funding... boppers Dec 2011 #19
thank you for the link....... MindMover Dec 2011 #32
I think the main problem MMJ discussions have are factual distortions. boppers Dec 2011 #35
Maybe because the goals of NIH are not what people think they are.....or MindMover Dec 2011 #39
I know that you read every link and substantive study on marijuana on the link I provided.....in 1hr MindMover Dec 2011 #21
let's look at the stats for those who go into treatment for cannabis RainDog Dec 2011 #24
I totally agree with your summation about treatment for marijuana and avoidance of jail time...... MindMover Dec 2011 #26
your link notes cannabis is no more addictive than caffeine RainDog Dec 2011 #20
oh yea boatloads of money, the average hourly wage is around 11 bucks....for drug counseling.... MindMover Dec 2011 #23
I'm not talking about you RainDog Dec 2011 #27
Yes, certain people are making a shitload of money off of prohibition.... MindMover Dec 2011 #29
I suppose I don't quite understand this statement, then RainDog Dec 2011 #33
I have already explained myself in other replies..... MindMover Dec 2011 #37
Indeed!! CanSocDem Dec 2011 #42
There is no habituation effect to THC. GliderGuider Dec 2011 #8
The stuff you smoked in Nam had a THC content of 7-8%...... MindMover Dec 2011 #11
Users quickly learn to titrate for the desired dose. GliderGuider Dec 2011 #12
I am not arguing your point of recreational substance use for various individual reasons..... MindMover Dec 2011 #13
OK, we have no major disagreements GliderGuider Dec 2011 #15
My experience has been that I have seen many clients/patients that have some minor MindMover Dec 2011 #41
it is totally disingenuous to compare cannabis to huffing gasoline RainDog Dec 2011 #18
Comparing substances is what I do to learn about them so that I can be more MindMover Dec 2011 #25
Because the govt doesn't want to study those who are regular users RainDog Dec 2011 #28
Thank you for these links, I have some good reading to do over these holidays..... MindMover Dec 2011 #31
there were 2700 separate studies published in 2009 RainDog Dec 2011 #34
I agree with everything you wrote with this exception..... MindMover Dec 2011 #36
something that is processed would qualify as a drug, imo RainDog Dec 2011 #40
a study of patients with MS found no increase in dosage - i.e. no tolerance RainDog Dec 2011 #16
When you can't get high anymore, it's time to take a break. DCKit Dec 2011 #30
I didn't watch this series but, it is fredamae Dec 2011 #9
didn't see this RainDog Dec 2011 #17
Total legalization of it would destroy his business model. boppers Dec 2011 #22
Money trumps doing the right thing - yet again - as always under capitalism slay Dec 2011 #38
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