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turbinetree

(24,695 posts)
20. I want to know what "early and late" mean in these "trials........
Wed Apr 29, 2020, 10:22 AM
Apr 2020
https://www.reuters.com/article/us-health-coronavirus-gilead-remdesivir/gilead-says-remdesivir-shows-improvement-in-covid-19-patients-when-used-early-idUSKBN22B1T9

where were the 397 people in the trial stages, where did they get the 62% and 49% result and did they do the following:


Physicians won’t get clarity until the medications have gone through what are known as randomized, controlled trials. In these kinds of clinical tests, half of a pool of patients is randomly given the drug, and the other half—the control group—is given an otherwise identical dosage that’s missing the active ingredient.

“If you don’t have a control, you will never know if a drug helped or harmed,” says Andre Kalil, a professor in the department of internal medicine at the University of Nebraska Medical Center.

https://www.nationalgeographic.com/science/2020/04/what-you-should-know-about-experimental-therapies-for-coronavirus/

And what about the lack of testing this country............just call me curious, what other maladies did these people have besides having the infection, did they use a placebo..................
Good news. Of course we will soon know that tRump himself developed this drug. groundloop Apr 2020 #1
LOL. He'll look like an even bigger fool. Most people have seen the light on his con. nt mobeau69 Apr 2020 #2
If the news is true, it's still a very limited help. Requires an IV, in a hospital setting. lagomorph777 Apr 2020 #8
Could be helpful in nursing homes. LisaL Apr 2020 #11
I don't think most nursing homes are actually equipped/staffed to deliver IVs. lagomorph777 Apr 2020 #12
I guess it would have to be a skilled nursing facility. LisaL Apr 2020 #13
Yeah, it may be much more practical than sending everybody to the hospital. lagomorph777 Apr 2020 #14
Most nursing facilities KatyMan Apr 2020 #49
This is true, but at least Steelrolled Apr 2020 #27
Could any of you fill us in on what the article says? luvtheGWN Apr 2020 #3
It's everywhere now. Try this from CNBC... mobeau69 Apr 2020 #4
Try this one LiberalArkie Apr 2020 #5
Thank you. luvtheGWN Apr 2020 #15
It might help with some by just knowing they are taking something for it. Placebo effect. LiberalArkie Apr 2020 #21
We are discussing several trials on one thread. LisaL Apr 2020 #26
It was a large randomized double-blind placebo study jpak Apr 2020 #46
This message was self-deleted by its author turbinetree Apr 2020 #6
WHO messed up big time by accidently releasing incomplete data from China, (supposedly), which still_one Apr 2020 #7
That study in China was on severely sick patients. LisaL Apr 2020 #9
That is what I heard also, but still it was still an incomplete trial. I am trying to understand still_one Apr 2020 #17
They will administer the drug in an infusion center or something like that. I am skeptical still_one Apr 2020 #19
That's what I was thinking. ananda Apr 2020 #22
Yes still_one Apr 2020 #29
All anti-viral drugs must be given early to be effective. LastDemocratInSC Apr 2020 #47
The WHO release of the China study DeminPennswoods Apr 2020 #10
Still the data should not have been released because it was incomplete, also it is a still_one Apr 2020 #18
It was treatment information, released AS incomplete and Hortensis Apr 2020 #31
This latest result showed definite shorter course of the disease and that is good still_one Apr 2020 #32
Fantastic if it turns out to be reliable as research continues. Hortensis Apr 2020 #35
+++ still_one Apr 2020 #37
The "China" Remdesivir study failed to enroll enough participants BlueIdaho Apr 2020 #39
I think WHO has lost much credibility over this crisis Steelrolled Apr 2020 #25
Well, Trump has frozen U.S. funding to WHO, which is most of it Hortensis Apr 2020 #33
Realistically I don't expect anything to change Steelrolled Apr 2020 #48
not about the drugs noneof_theabove Apr 2020 #16
I want to know what "early and late" mean in these "trials........ turbinetree Apr 2020 #20
Bingo mjvpi Apr 2020 #23
What I found interesting was that when you add 62%+49% it does not equal 100 turbinetree Apr 2020 #24
It shouldn't add to a 100 % because they are talking about patients released from the hospital LisaL Apr 2020 #34
It's a real shame when positive news about development of a drug results in Hortensis Apr 2020 #28
I guess it's big pharma or something like that, and we are better off LisaL Apr 2020 #38
:) Seemingly. Of course when we finally do have medication Hortensis Apr 2020 #45
JFTR: OilemFirchen Apr 2020 #30
These companies put a lot of money and effort into drug development. LisaL Apr 2020 #36
Non-sequitur. OilemFirchen Apr 2020 #40
Would you say the same about AIDS drugs BlueIdaho Apr 2020 #41
Asked and answered above. (n/t) OilemFirchen Apr 2020 #42
So that's a yes... then... BlueIdaho Apr 2020 #43
Huh? OilemFirchen Apr 2020 #44
Yet, the British trial was NS JCMach1 Apr 2020 #50
Significance depends on the number of participants. LisaL Apr 2020 #51
I just really dislike false hope articles like the OP JCMach1 Apr 2020 #52
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