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bluedye33139

(1,474 posts)

10. In HIV medication, they actually use this mechanism on purpose

Reply to soothsayer (Reply #9)

Mon Oct 12, 2020, 06:13 AM

Oct 2020

Most HIV medications are administered with a booster, another drug that depletes the cytochrome p450 so that the medication is not broken down by the liver as quickly. You're not crazy, exploiting this mechanism really is something that doctors and researchers are looking into.

The danger of course with most medications is that you'll end up with too much in the bloodstream, and with some medications this is very dangerous. With other medications, it's not so dangerous.

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20 replies

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Highlight:

Grapefruit Is One of the Weirdest Fruits on the Planet {Drug interactions ! } (Atlas Obscura) [View all] eppur_se_muova Oct 2020 OP

Yes, I miss grapefruit. Haven't had any for many years; taking Lipitor... No Vested Interest Oct 2020 #1

Same here. I love grapefruit. nt CozyMystery Oct 2020 #14

I have definitely noticed, Onyrleft Oct 2020 #2

MOST interesting. Duppers Oct 2020 #3

Murder mystery plot NJCher Oct 2020 #4

does Trump like grapefruit? kiri Oct 2020 #5

it did say they have no idea how many ppl died because of this interaction..YIKES!!! samnsara Oct 2020 #17

I hate it MFM008 Oct 2020 #6

I had stent implants in 2004 DFW Oct 2020 #7

i LOVE grapefruit, so when i was given prescriptions. i asked if they were grapefruit safe. pansypoo53219 Oct 2020 #8

At last, the explanation I've longed for! soothsayer Oct 2020 #9

In HIV medication, they actually use this mechanism on purpose bluedye33139 Oct 2020 #10

Right. Fascinating! Thank you soothsayer Oct 2020 #11

Thanks, that was very informative. nt eppur_se_muova Oct 2020 #15

That's a real good question... druidity33 Oct 2020 #12

The comment right above yours says yes! Check it out soothsayer Oct 2020 #13

cuz ppl would still eat grapefruit then they would have twice the GF probs... samnsara Oct 2020 #18

Hmm. But if the meds are 1/10 as strong.... soothsayer Oct 2020 #19

this article was fascinating! Hubby is a Pharmacist and knew about the interactions and he always.. samnsara Oct 2020 #16

Article states that lime has same effect as grapefruit wishstar Oct 2020 #20