- snip - Musk’s frustration with the Fed rate hike hikes goes back a ways. In December, he blamed the central bank for the steep drop in Tesla stock—last year the carmaker’s shares fell 65% and it lost $700 billion in market valuation—arguing interest rate hikes had made the stock market less appealing to investors.

The story of the hunt for Covid’s origin is partly about the stonewalling by China that has left scientists with incomplete evidence, all of it about a virus that is constantly changing. For all the data suggesting that the virus may have jumped into people from wild animals at a Chinese market, conclusive proof remains out of reach, as it does for the competing hypothesis that the virus leaked from a lab.
But the story is also about politics and how both Democrats and Republicans have filtered the available evidence through their partisan lenses.

Some Republicans grew fixated on idea of a lab leak after former President Donald J. Trump raised it in the early months of the pandemic despite scant evidence supporting it. That turned the theory toxic for many Democrats, who viewed it as an effort by Mr. Trump to distract from his administration’s failings in containing the spread of the virus.

The intense political debate, now in its fourth year, has at times turned scientists into lobbyists, competing for policymakers’ time and favor. Dr. Relman is just one of several researchers and like-minded thinkers who has successfully worked the corridors of power in Washington to force journalists, policymakers and skeptical Democrats to take the lab leak idea seriously.

But the political momentum has not always aligned with the evidence. Even as the idea of an accidental lab leak has now gained standing in Washington, findings reported last week bolstered the market theory. Mining a trove of genetic data taken from swabs at the Huanan Seafood Wholesale Market in Wuhan in early 2020, virus experts said they found samples containing genetic material from both the coronavirus and illegally traded raccoon dogs. The finding, while hardly conclusive, pointed to an infected animal.

The new data from the market suggests that China is holding onto clues that could reshape the debate. But for now, at least, the idea of a lab leak seems to have prevailed in the court of public opinion: Two recent polls show that roughly two-thirds of Americans believe that Covid probably started in a lab.

- NYTimes, Global Health, Dec. 19, 2021 -
- snip - A growing body of preliminary research suggests the Covid vaccines used in most of the world offer almost no defense against becoming infected by the highly contagious Omicron variant.

All vaccines still seem to provide a significant degree of protection against serious illness from Omicron, which is the most crucial goal. But only the Pfizer and Moderna shots, when reinforced by a booster, appear to have initial success at stopping infections, and these vaccines are unavailable in most of the world.

The other shots — including those from AstraZeneca, Johnson & Johnson and vaccines manufactured in China and Russia — do little to nothing to stop the spread of Omicron, early research shows. And because most countries have built their inoculation programs around these vaccines, the gap could have a profound impact on the course of the pandemic.

The disparity in the ability of countries to weather the pandemic will almost certainly deepen. And the news about limited vaccine efficacy against Omicron infection could depress demand for vaccination throughout the developing world, where many people are already hesitant or preoccupied with other health problems.

Antibodies are the first line of defense induced by vaccines. But the shots also stimulate the growth of T cells, and preliminary studies suggest that these T cells still recognize the Omicron variant, which is important in preventing severe disease.
“What you lose first is protection against asymptomatic mild infection, what you retain much better is protection against severe disease and death,” said John Moore, a virologist at Weill Cornell Medicine in New York. He called it “a silver lining” that Omicron so far appears less lethal than the Delta variant.

The volume and tenor of pleas for help escalated to new heights this past week as India was engulfed in the pandemic.

You’ve likely seen images of numerous funeral pyres and many graves along with sick outside overfull hospitals.

Apart from the pyres, it looks like Wuhan in January 2020, the U.S. in March 2020, and Brazil at the end of this March.

And yet there is something really wrong here, very off. The case counts and deaths are truths which can’t be escaped but the insistence the U.S. somehow is failing to meet India’s needs is off base. - snip -


- snip - In the mean time invective against the Biden administration and Big Pharma has continued, some of it based in what looks like weak and less-than-thorough reporting.

Claims that Big Pharma has decided profits come before the lives of India’s people follow reports that Big Pharma refused to give India patents or transfer intellectual property.

Except that Big Pharma is represented in India by AstraZeneca, which is making their adenovirus-vector vaccine in country. It’s the same vaccine which has been used in Europe, and is still in FDA safety review here.

India also has its own Big Pharma in Bharat Biotech, which has developed Covaxin vaccine in collaboration with Washington University School of Medicine in St. Louis, Missouri. The vaccine left Phase 3 trials in early January.

Yet intelligent people continue to harangue the U.S. and Big Pharma about their refusal to help India with the IP needed for licensing. They retweet stuff like this:



The account that wrote this was opened only weeks ago in January 2021. There’s almost nothing in its profile to suggest this is a human with credible background education or experience; the account hasn’t been validated by Twitter. Note the number of times this has been shared by retweet or quote tweet, yet the majority of roughly 6000 tweets by this account are about pop culture.

This is the kind of social media content which ramped up tension around U.S. response to India’s ongoing COVID surge and continues to do so because it remains uncontested.

The issue the tweet focused on was vaccine manufacturers’ request for indemnification by countries which use its vaccine or licensing to manufacture vaccines. How odd that an account tweeting about beauty products and the Kardashians chose to phrase indemnification this way. - snip -

Except the photo Mr. Rubio posted was not of Mr. Lewis, but of another congressman: Representative Elijah E. Cummings, who died in October. Mr. Rubio also used the photo of himself with Mr. Cummings as his Twitter profile picture for a brief time.

- snip -- The revelation that a coronavirus death took place in the United States in early February shifts the understanding of its arrival in this country and changes the picture of what the nation was contending with by the time government officials began taking action.
-- The first Covid-19 death in the United States had previously been thought to be on Feb. 26 in Seattle, one of the worst-hit cities in the country.
-- Officials in Santa Clara County said Wednesday that a newly discovered coronavirus-linked death Feb. 6, the earliest known death in the United States caused by the virus, was one of more than a dozen deaths in the county that the medical examiner had suspicions about and ordered investigated.

- snip -- The Feb. 6 death was a 57-year-old woman who died at her home in Silicon Valley, officials said Wednesday.
-- The announcement has reset the timeline of the spread of infection in the United States.
-- Officials have said that the death was believed to have been the result of community spread, not travel to another country.